Descriptors for Artemisinin and its Derivatives; Estimation of Physicochemical and Biochemical Data

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Article on descriptors for artemisinin and its derivatives and an estimation of physiochemical and biochemical data.

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11 p.: ill.

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Abraham, M. H. (Michael H.) & Acree, William E. (William Eugene) Creation Date: Unknown.

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Article on descriptors for artemisinin and its derivatives and an estimation of physiochemical and biochemical data.

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11 p.: ill.

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Copyright © 2013, European Chemical Bulletin. All rights reserved.

Abstract: Properties, or descriptors, of artemisinin and some of its derivatives have been obtained from known solubilities and water-octanol partition coefficients. These descriptors can then be combined with already known equations to yield water-solvent partition coefficients and solubilities in a very large number of solvents, so that it is now possible to select suitable solvents for purification, etc. Combination of the descriptors with known equations for blood-tissue partitions enables partition coefficients to be estimated for partitions from blood to brain, muscle, liver, lung, kidney, heart, skin and fat. Where data on blood-tissue partitions exist, there is agreement with experiment.

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  • European Chemical Bulletin, 2013, Hungary: Deuton-X Ltd., pp. 1027-1037

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  • Publication Title: European Chemical Bulletin
  • Volume: 2
  • Issue: 12
  • Page Start: 1027
  • Page End: 1037
  • Peer Reviewed: Yes

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  • 2013

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  • Sept. 13, 2013, 2:58 p.m.

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  • Feb. 24, 2014, 3:46 p.m.

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Abraham, M. H. (Michael H.) & Acree, William E. (William Eugene). Descriptors for Artemisinin and its Derivatives; Estimation of Physicochemical and Biochemical Data, article, Date Unknown; [Hungary]. (digital.library.unt.edu/ark:/67531/metadc181655/: accessed August 20, 2017), University of North Texas Libraries, Digital Library, digital.library.unt.edu; crediting UNT College of Arts and Sciences.