Solubility of Benzodiazepines in Polyethylene Glycol 200 + Water Mixtures at 303.2 K Metadata
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- Main Title Solubility of Benzodiazepines in Polyethylene Glycol 200 + Water Mixtures at 303.2 K
Author: Jouyban, AbolghasemCreator Type: PersonalCreator Info: Tabriz University of Medical Sciences
Author: Shokri, JavadCreator Type: PersonalCreator Info: Tabriz University of Medical Sciences
Author: Barzegar-Jalali, MohammadCreator Type: PersonalCreator Info: Tabriz University of Medical Sciences
Author: Hassanzadeh, DavoudCreator Type: PersonalCreator Info: Tabriz University of Medical Sciences
Author: Acree, William E. (William Eugene)Creator Type: PersonalCreator Info: University of North Texas
Author: Ghafourian, TaravatCreator Type: PersonalCreator Info: Universities of Kent and Greenwich
Author: Nokhodchi, AliCreator Type: PersonalCreator Info: Universities of Kent and Greenwich
Name: American Chemical SocietyPlace of Publication: [Washington, D.C.]
- Creation: 2009-06-15
- Content Description: Article discussing the solubility of benzodiazepines in polyethylene glycol 200 plus water mixtures at 303.2 K.
- Physical Description: 4 p.
- Keyword: benzodiazepines
- Keyword: polyethylene glycol
- Keyword: chlordiazepoxide
- Keyword: diazepam
- Journal: Journal of Chemical and Engineering Data, 2009, Washington D.C.: American Chemical Society, pp. 519-522
- Publication Title: Journal of Chemical and Engineering Data
- Volume: 55
- Issue: 1
- Page Start: 519
- Page End: 522
- Peer Reviewed: True
Name: UNT Scholarly WorksCode: UNTSW
Name: UNT College of Arts and SciencesCode: UNTCAS
- Rights Access: public
- DOI: 10.1021/je90033p
- Archival Resource Key: ark:/67531/metadc172356
- Academic Department: Chemistry
- Display Note: Reprinted with permission from the Journal of Chemical and Engineering Data. Copyright 2009 American Chemical Society.
- Display Note: Abstract: Experimental solubilities of chlordiazepoxide, diazepam, and lorazepam in polyethylene glycol 200 (PEG 200) + water mixtures at 303.2 K were reported. The solubility of each drug increased exponentially with the addition of PEG 200 and reached the maximum value in neat PEG 200. The Jouyban−Acree model was used to mathematically describe the experimental data, and the solubilities were predicted using a previously trained version of the Jouyban−Acree model for PEG + water mixtures and the solubility data in monosolvents. The overall mean relative deviations of the models were 3.7% and 18.3%, respectively, for the fitted model and the trained version.