Solubility of Benzodiazepines in Polyethylene Glycol 200 + Water Mixtures at 303.2 K Metadata

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Title

  • Main Title Solubility of Benzodiazepines in Polyethylene Glycol 200 + Water Mixtures at 303.2 K

Creator

  • Author: Jouyban, Abolghasem
    Creator Type: Personal
    Creator Info: Tabriz University of Medical Sciences
  • Author: Shokri, Javad
    Creator Type: Personal
    Creator Info: Tabriz University of Medical Sciences
  • Author: Barzegar-Jalali, Mohammad
    Creator Type: Personal
    Creator Info: Tabriz University of Medical Sciences
  • Author: Hassanzadeh, Davoud
    Creator Type: Personal
    Creator Info: Tabriz University of Medical Sciences
  • Author: Acree, William E. (William Eugene)
    Creator Type: Personal
    Creator Info: University of North Texas
  • Author: Ghafourian, Taravat
    Creator Type: Personal
    Creator Info: Universities of Kent and Greenwich
  • Author: Nokhodchi, Ali
    Creator Type: Personal
    Creator Info: Universities of Kent and Greenwich

Publisher

  • Name: American Chemical Society
    Place of Publication: [Washington, D.C.]

Date

  • Creation: 2009-06-15

Language

  • English

Description

  • Content Description: Article discussing the solubility of benzodiazepines in polyethylene glycol 200 plus water mixtures at 303.2 K.
  • Physical Description: 4 p.

Subject

  • Keyword: benzodiazepines
  • Keyword: polyethylene glycol
  • Keyword: chlordiazepoxide
  • Keyword: diazepam

Source

  • Journal: Journal of Chemical and Engineering Data, 2009, Washington D.C.: American Chemical Society, pp. 519-522

Citation

  • Publication Title: Journal of Chemical and Engineering Data
  • Volume: 55
  • Issue: 1
  • Page Start: 519
  • Page End: 522
  • Peer Reviewed: True

Collection

  • Name: UNT Scholarly Works
    Code: UNTSW

Institution

  • Name: UNT College of Arts and Sciences
    Code: UNTCAS

Rights

  • Rights Access: public

Resource Type

  • Article

Format

  • Text

Identifier

  • DOI: 10.1021/je90033p
  • Archival Resource Key: ark:/67531/metadc172356

Degree

  • Academic Department: Chemistry

Note

  • Display Note: Reprinted with permission from the Journal of Chemical and Engineering Data. Copyright 2009 American Chemical Society.
  • Display Note: Abstract: Experimental solubilities of chlordiazepoxide, diazepam, and lorazepam in polyethylene glycol 200 (PEG 200) + water mixtures at 303.2 K were reported. The solubility of each drug increased exponentially with the addition of PEG 200 and reached the maximum value in neat PEG 200. The Jouyban−Acree model was used to mathematically describe the experimental data, and the solubilities were predicted using a previously trained version of the Jouyban−Acree model for PEG + water mixtures and the solubility data in monosolvents. The overall mean relative deviations of the models were 3.7% and 18.3%, respectively, for the fitted model and the trained version.