Solubility of Benzodiazepines in Polyethylene Glycol 200 + Water Mixtures at 303.2 K

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Article discussing the solubility of benzodiazepines in polyethylene glycol 200 plus water mixtures at 303.2 K.

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4 p.

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Jouyban, Abolghasem; Shokri, Javad; Barzegar-Jalali, Mohammad; Hassanzadeh, Davoud; Acree, William E. (William Eugene); Ghafourian, Taravat et al. June 15, 2009.

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Article discussing the solubility of benzodiazepines in polyethylene glycol 200 plus water mixtures at 303.2 K.

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4 p.

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Reprinted with permission from the Journal of Chemical and Engineering Data. Copyright 2009 American Chemical Society.

Abstract: Experimental solubilities of chlordiazepoxide, diazepam, and lorazepam in polyethylene glycol 200 (PEG 200) + water mixtures at 303.2 K were reported. The solubility of each drug increased exponentially with the addition of PEG 200 and reached the maximum value in neat PEG 200. The Jouyban−Acree model was used to mathematically describe the experimental data, and the solubilities were predicted using a previously trained version of the Jouyban−Acree model for PEG + water mixtures and the solubility data in monosolvents. The overall mean relative deviations of the models were 3.7% and 18.3%, respectively, for the fitted model and the trained version.

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  • Journal of Chemical and Engineering Data, 2009, Washington D.C.: American Chemical Society, pp. 519-522

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  • Publication Title: Journal of Chemical and Engineering Data
  • Volume: 55
  • Issue: 1
  • Page Start: 519
  • Page End: 522
  • Peer Reviewed: Yes

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UNT Scholarly Works

The Scholarly Works Collection is home to materials from the University of North Texas community's research, creative, and scholarly activities and serves as UNT's Open Access Repository. It brings together articles, papers, artwork, music, research data, reports, presentations, and other scholarly and creative products representing the expertise in our university community. Access to some items in this collection may be restricted.

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  • June 15, 2009

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  • June 28, 2013, 2:11 p.m.

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  • Jan. 9, 2015, 4:03 p.m.

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Jouyban, Abolghasem; Shokri, Javad; Barzegar-Jalali, Mohammad; Hassanzadeh, Davoud; Acree, William E. (William Eugene); Ghafourian, Taravat et al. Solubility of Benzodiazepines in Polyethylene Glycol 200 + Water Mixtures at 303.2 K, article, June 15, 2009; [Washington, D.C.]. (digital.library.unt.edu/ark:/67531/metadc172356/: accessed April 25, 2017), University of North Texas Libraries, Digital Library, digital.library.unt.edu; crediting UNT College of Arts and Sciences.