Neuromagnetic source reconstruction

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In neuromagnetic source reconstruction, a functional map of neural activity is constructed from noninvasive magnetoencephalographic (MEG) measurements. The overall reconstruction problem is under-determined, so some form of source modeling must be applied. We review the two main classes of reconstruction techniques-parametric current dipole models and nonparametric distributed source reconstructions. Current dipole reconstructions use a physically plausible source model, but are limited to cases in which the neural currents are expected to be highly sparse and localized. Distributed source reconstructions can be applied to a wider variety of cases, but must incorporate an implicit source, model in order to arrive at ... continued below

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4 p.

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Lewis, P. S.; Mosher, J. C. & Leahy, R. M. December 31, 1994.

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In neuromagnetic source reconstruction, a functional map of neural activity is constructed from noninvasive magnetoencephalographic (MEG) measurements. The overall reconstruction problem is under-determined, so some form of source modeling must be applied. We review the two main classes of reconstruction techniques-parametric current dipole models and nonparametric distributed source reconstructions. Current dipole reconstructions use a physically plausible source model, but are limited to cases in which the neural currents are expected to be highly sparse and localized. Distributed source reconstructions can be applied to a wider variety of cases, but must incorporate an implicit source, model in order to arrive at a single reconstruction. We examine distributed source reconstruction in a Bayesian framework to highlight the implicit nonphysical Gaussian assumptions of minimum norm based reconstruction algorithms. We conclude with a brief discussion of alternative non-Gaussian approachs.

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4 p.

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OSTI; NTIS; GPO Dep.

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  • IEEE conference on acoustics, speech and signal processing,Detroit, MI (United States),8-12 May 1995

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  • Other: DE95005242
  • Report No.: LA-UR--94-4378
  • Report No.: CONF-9505158--1
  • Grant Number: W-7405-ENG-36
  • DOI: 10.1097/00006534-199407000-00071 | External Link
  • Office of Scientific & Technical Information Report Number: 10115240
  • Archival Resource Key: ark:/67531/metadc1275458

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  • December 31, 1994

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  • Oct. 12, 2018, 6:44 a.m.

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  • Nov. 13, 2018, 1:29 p.m.

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Lewis, P. S.; Mosher, J. C. & Leahy, R. M. Neuromagnetic source reconstruction, article, December 31, 1994; New Mexico. (https://digital.library.unt.edu/ark:/67531/metadc1275458/: accessed March 21, 2019), University of North Texas Libraries, Digital Library, https://digital.library.unt.edu; crediting UNT Libraries Government Documents Department.