Cytochemistry of Delayed Radionecrosis of the Murine Spinal Cord

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In the vast field of radiation pathology we find pathologists, anatomists, and even physiologists busily at work, but the radiobiologist is conspicuously absent, although, according to Zirkle (1959), this field is clearly within his domain. Perhaps it is wise to take this broad hint of the scientifically so well equipped radiobiologist and to stay clear from an area in which an incalculable array of variables makes clearcut experimentation a hopeless venture, a priori. Perhaps it would be better if the pathologist, who must study pertinent material, restricts himself humbly to the recording of his observations, refraining from any attempt at … continued below

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Zeman, Wolfgang October 15, 1963.

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In the vast field of radiation pathology we find pathologists, anatomists, and even physiologists busily at work, but the radiobiologist is conspicuously absent, although, according to Zirkle (1959), this field is clearly within his domain. Perhaps it is wise to take this broad hint of the scientifically so well equipped radiobiologist and to stay clear from an area in which an incalculable array of variables makes clearcut experimentation a hopeless venture, a priori. Perhaps it would be better if the pathologist, who must study pertinent material, restricts himself humbly to the recording of his observations, refraining from any attempt at interpretation. On the other hand, since seemingly audacious speculation has borne fruit in the past and the value of the information that results, if the speculation proves to be correct, is worth many times the effort, there is obvious justification for a thesis on the mechanism of delayed radionecrosis.

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  • October 15, 1963

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  • Feb. 5, 2022, 9:58 a.m.

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  • Jan. 29, 2023, 3:40 a.m.

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Zeman, Wolfgang. Cytochemistry of Delayed Radionecrosis of the Murine Spinal Cord, report, October 15, 1963; Washington D.C.. (https://digital.library.unt.edu/ark:/67531/metadc1255876/: accessed July 16, 2025), University of North Texas Libraries, UNT Digital Library, https://digital.library.unt.edu; crediting UNT Libraries Government Documents Department.

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