The Effects of 250-kv X-Ray on the Dog's Pancreas: Morphological and Functional Changes

One of 624 reports in the series: BNL (Series) available on this site.
Thumbnail image of item number 1 in: 'The Effects of 250-kv X-Ray on the Dog's Pancreas: Morphological and Functional Changes'.
Thumbnail image of item number 2 in: 'The Effects of 250-kv X-Ray on the Dog's Pancreas: Morphological and Functional Changes'.
Thumbnail image of item number 3 in: 'The Effects of 250-kv X-Ray on the Dog's Pancreas: Morphological and Functional Changes'.
Thumbnail image of item number 4 in: 'The Effects of 250-kv X-Ray on the Dog's Pancreas: Morphological and Functional Changes'.
Showing 1-4 of 28 pages in this report.

PDF Version Also Available for Download.

Description

Previous investigations that the pancreas is a radioresistant organ. Ivy in 1924 noted the presence of a fibrotic atrophic pancreas in a dog which had received one erythema dose to the epigastrium. Fisher in 1923 reported that four to five erythema doses delivered in a single application caused complete disappearance of the irradiated pancreatic remnant in about two months. These dogs died because of uncontrolled diabetes. One dog that received four erythema doses (possibly 200 r) was sacrificed after five months. At autopsy the irradiated pancreas had disappeared, but 275 mgm of regenerated pancreas were found at the base of … continued below

Creation Information

Archamefau, John; Griem, Melvin & Harper, Paul February 1, 1963.

Context

This report is part of the collection entitled: TRAIL Microcard Collection and was provided by the UNT Libraries Government Documents Department to the UNT Digital Library, a digital repository hosted by the UNT Libraries. More information about this report can be viewed below.

Who

People and organizations associated with either the creation of this report or its content.

Authors

Originator

Sponsor

Publisher

Audiences

We've identified this report as a primary source within our collections. Researchers, educators, and students may find this report useful in their work.

Provided By

UNT Libraries Government Documents Department

Serving as both a federal and a state depository library, the UNT Libraries Government Documents Department maintains millions of items in a variety of formats. The department is a member of the FDLP Content Partnerships Program and an Affiliated Archive of the National Archives.

About | Browse this Partner

Contact Us

Corrections Questions

What

Descriptive information to help identify this report. Follow the links below to find similar items on the Digital Library.

Titles

Description

Previous investigations that the pancreas is a radioresistant organ. Ivy in 1924 noted the presence of a fibrotic atrophic pancreas in a dog which had received one erythema dose to the epigastrium. Fisher in 1923 reported that four to five erythema doses delivered in a single application caused complete disappearance of the irradiated pancreatic remnant in about two months. These dogs died because of uncontrolled diabetes. One dog that received four erythema doses (possibly 200 r) was sacrificed after five months. At autopsy the irradiated pancreas had disappeared, but 275 mgm of regenerated pancreas were found at the base of the main duct and 100 mgm at the base of the accessory duct. Leven in 1933 implanted radon seeds into the pancreas. Dosages varied from 528 to 1584 millicurie hours. At postmorten the pancreas surrounding the seeds demonstrated fibrous atropy and foci of necrosis. The islets appeared normal but were relatively larger in size. Rauch in 1952 reported that dogs given 200 r in air over the pancreas on alternate days until a total of 1600 r was received failed to show any histological changes after two months. Lushbaugh and Spalding and Lushbaugh reported that over 1500 r of whole-body gamma irradiation were required to produce histologic changes in alpha cells in 8 hours, and over 5000 r to produce changes in the beta cells in the same time. These changes had disappeared by 24 hours.

Notes

Digitized from microopaque cards (2).

Language

Item Type

Identifier

Unique identifying numbers for this report in the Digital Library or other systems.

Collections

This report is part of the following collections of related materials.

TRAIL Microcard Collection

Imaged from microcard, these technical reports describe research performed for U.S. government agencies from the 1930s to the 1960s. The reports were provided by the Technical Report Archive and Image Library (TRAIL).

About | Browse this Collection

Technical Report Archive and Image Library

The Technical Report Archive & Image Library (TRAIL) identifies, acquires, catalogs, digitizes and provides unrestricted access to U.S. government agency technical reports. The mission of TRAIL is to ensure preservation, discoverability, and persistent open access to government technical publications regardless of form or format.

About | Browse this Collection

What responsibilities do I have when using this report?

Digital Files

When

Dates and time periods associated with this report.

Creation Date

  • February 1, 1963

Added to The UNT Digital Library

  • Feb. 5, 2022, 9:42 a.m.

Description Last Updated

  • Oct. 10, 2022, 4:26 a.m.

Usage Statistics

When was this report last used?

Yesterday: 0
Past 30 days: 0
Total Uses: 4
More Statistics

Where

Geographical information about where this report originated or about its content.

Place Name

Publication Place

Map Information

  • map marker Place Name coordinates. (May be approximate.)
  • Repositioning map may be required for optimal printing.

Mapped Locations

Interact With This Report

Here are some suggestions for what to do next.

Start Reading

Thumbnail image of item number 1 in: 'The Effects of 250-kv X-Ray on the Dog's Pancreas: Morphological and Functional Changes'.
Thumbnail image of item number 2 in: 'The Effects of 250-kv X-Ray on the Dog's Pancreas: Morphological and Functional Changes'.
Thumbnail image of item number 3 in: 'The Effects of 250-kv X-Ray on the Dog's Pancreas: Morphological and Functional Changes'.
Thumbnail image of item number 4 in: 'The Effects of 250-kv X-Ray on the Dog's Pancreas: Morphological and Functional Changes'.

PDF Version Also Available for Download.

Citations, Rights, Re-Use

International Image Interoperability Framework

IIF Logo

We support the IIIF Presentation API

Links for Robots

Helpful links in machine-readable formats.

Archival Resource Key (ARK)

International Image Interoperability Framework (IIIF)

Metadata Formats

Images

URLs

Stats

Archamefau, John; Griem, Melvin & Harper, Paul. The Effects of 250-kv X-Ray on the Dog's Pancreas: Morphological and Functional Changes, report, February 1, 1963; Washington D.C.. (https://digital.library.unt.edu/ark:/67531/metadc1250524/: accessed September 12, 2026), University of North Texas Libraries, UNT Digital Library, https://digital.library.unt.edu; crediting UNT Libraries Government Documents Department.

Back to Top of Screen