Indirect Effect of X-Radiation on Bone Growth in Rats

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It has been known for many years that bone growth may be retarded by relatively large doses of therapeutic radiation. Similar doses of radiation have also shown retarded growth in animals. More recently, reports of studies of Japanese children exposed to the Atomic Bomb Detentions at Hiroshima and Nagasaki and Marshallese children exposed to radiation in the fallout accident of 1954 have indicated some impairment in their growth and development, possibly related to radiation exposure. Since the doses of radiation received by these children were lower than would be expected to produce retardation of bone growth by direct irradiation, it … continued below

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Conard, R. A. February 1, 1963.

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It has been known for many years that bone growth may be retarded by relatively large doses of therapeutic radiation. Similar doses of radiation have also shown retarded growth in animals. More recently, reports of studies of Japanese children exposed to the Atomic Bomb Detentions at Hiroshima and Nagasaki and Marshallese children exposed to radiation in the fallout accident of 1954 have indicated some impairment in their growth and development, possibly related to radiation exposure. Since the doses of radiation received by these children were lower than would be expected to produce retardation of bone growth by direct irradiation, it was considered that indirect mechanisms might play a part. This preliminary report summarizes investigations of possible indirect effects of X-irradiation in bone growth in rats.

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  • February 1, 1963

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  • Feb. 5, 2022, 9:42 a.m.

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  • Oct. 8, 2022, 4:25 a.m.

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Conard, R. A. Indirect Effect of X-Radiation on Bone Growth in Rats, report, February 1, 1963; Washington D.C.. (https://digital.library.unt.edu/ark:/67531/metadc1250518/: accessed June 21, 2025), University of North Texas Libraries, UNT Digital Library, https://digital.library.unt.edu; crediting UNT Libraries Government Documents Department.

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