Solubility and Apparent Specific Volume of Sucrose in Some Aqueous Polyethylene Glycol Mixtures at 298.2 K

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This article determines and correlates the equilibrium solubility of sucrose in {PEG 200 (or 400) + water} mixtures at 298.2 K.

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5 p.

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Tinjacá, Darío; Muñoz, María M.; Rahimpour, Elaheh; Jouyban, Abolghasem; Martínez, Fleming & Acree, William E. (William Eugene) June 20, 2018.

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This article determines and correlates the equilibrium solubility of sucrose in {PEG 200 (or 400) + water} mixtures at 298.2 K.

Physical Description

5 p.

Notes

Abstract: Background: Sucrose is the most widely used sweetener in food and pharmaceuticals.
Quantitative solubility values of this excipient in aqueous polyethylene glycol (PEG)
mixtures is not abundant. Thus, the main objective of this research was to determine and
correlate the equilibrium solubility of sucrose in {PEG 200 (or 400) + water} mixtures at
298.2 K.
Methods: Shaken flask method was used to determine isothermal solubility. Concentration
measurements were performed by means of density determinations. Jouyban-Acree model
was used to correlate both solubility sets.
Results: Solubility of sucrose decreases non-linearly with the addition of either PEG200
or PEG400 to water. Jouyban-Acree model correlates solubility values with mixtures
composition for both cosolvent systems. Moreover, apparent specific volume of sucrose
were also calculated from density and compositions.
Conclusion: Useful solubility values of sucrose at equilibrium in aqueous mixtures of
PEG200 and PEG400, as well as their volumetric contributions to saturated solutions are
reported.

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  • Pharmaceutical Sciences, 2018. Tabriz, Iran: Tabriz University of Medical Sciences

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Publication Information

  • Publication Title: Pharmaceutical Sciences
  • Volume: 24
  • Pages: 163-167
  • Peer Reviewed: Yes

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  • June 20, 2018

Submitted Date

  • December 21, 2017

Accepted Date

  • March 20, 2018

Added to The UNT Digital Library

  • June 26, 2018, 9:56 p.m.

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Tinjacá, Darío; Muñoz, María M.; Rahimpour, Elaheh; Jouyban, Abolghasem; Martínez, Fleming & Acree, William E. (William Eugene). Solubility and Apparent Specific Volume of Sucrose in Some Aqueous Polyethylene Glycol Mixtures at 298.2 K, article, June 20, 2018; Tabriz, Iran. (digital.library.unt.edu/ark:/67531/metadc1181165/: accessed November 18, 2018), University of North Texas Libraries, Digital Library, digital.library.unt.edu; crediting UNT College of Arts and Sciences.