Status of human chromosome aberrations as a biological radiation dosimeter in the nuclear industry

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It seems that the determination of peripheral lymphocyte chriomosome aberration levels is now firmly established as a means of biological dosimetry of great value in many phases of the nuclear industry. In the case of large external exposure it can provide valuable quantitative estimates, as well as information on dose distribution and radiation quality. In the case of routine occupational exposures the technique is more qualitative, but is of value particularly in resolving uncertainties as to whether suspected overexposures did in fact occur. Where workers accumulate burdens of internal emitters, aberration analysis provides a valuable, though at present quite qualitative ... continued below

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Pages: 38

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Bender, M.A. January 1, 1978.

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Description

It seems that the determination of peripheral lymphocyte chriomosome aberration levels is now firmly established as a means of biological dosimetry of great value in many phases of the nuclear industry. In the case of large external exposure it can provide valuable quantitative estimates, as well as information on dose distribution and radiation quality. In the case of routine occupational exposures the technique is more qualitative, but is of value particularly in resolving uncertainties as to whether suspected overexposures did in fact occur. Where workers accumulate burdens of internal emitters, aberration analysis provides a valuable, though at present quite qualitative indicator. In spite of the expense of cytogenetic analyses, they are of sufficient value to justify much more widespread application, particularly in high risk situations.

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Pages: 38

Notes

Dep. NTIS, PC A03/MF A01.

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  • IAEA advisory group Routine use of chromosome analysis in radiation protection, Paris, France, 5 Dec 1978

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  • Report No.: BNL-25281
  • Report No.: CONF-781215-2
  • Grant Number: EY-76-C-02-0016
  • Office of Scientific & Technical Information Report Number: 6203328
  • Archival Resource Key: ark:/67531/metadc1111992

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Office of Scientific & Technical Information Technical Reports

Reports, articles and other documents harvested from the Office of Scientific and Technical Information.

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  • January 1, 1978

Added to The UNT Digital Library

  • Feb. 22, 2018, 7:45 p.m.

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  • March 23, 2018, 1:31 p.m.

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Bender, M.A. Status of human chromosome aberrations as a biological radiation dosimeter in the nuclear industry, article, January 1, 1978; United States. (digital.library.unt.edu/ark:/67531/metadc1111992/: accessed April 21, 2018), University of North Texas Libraries, Digital Library, digital.library.unt.edu; crediting UNT Libraries Government Documents Department.