Solvent-refined-coal (SRC) process: health programs. Research and development report No. 53, Interim report No. 39. Volume III. Pilot plant development work. Part 4: Industrial hygiene, clinical and toxicological programs. Final report of subcontract No. 10, June 1, 1976-June 9, 1978

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This report summarizes the toxicological studies on SRC-I materials completed under Subcontract No. 10 as part of the Health Programs under the Solvent Refined Coal (SRC) Process Contract during the total period of the subcontract, June 1, 1976 through June 9, 1978. The studies were conducted by Industrial Bio-Test Laboratories (IBT) as the subcontractor. A number of acute studies were completed on the products and intermediate streams as well as several subchronic studies. In addition, preliminary dose-ranging, or pilot, studies were completed. None of the materials exhibited high toxicities when administered orally, dermally, or by the inhalation route. Three of ... continued below

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Pages: 105

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Creator: Unknown. November 1, 1981.

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Description

This report summarizes the toxicological studies on SRC-I materials completed under Subcontract No. 10 as part of the Health Programs under the Solvent Refined Coal (SRC) Process Contract during the total period of the subcontract, June 1, 1976 through June 9, 1978. The studies were conducted by Industrial Bio-Test Laboratories (IBT) as the subcontractor. A number of acute studies were completed on the products and intermediate streams as well as several subchronic studies. In addition, preliminary dose-ranging, or pilot, studies were completed. None of the materials exhibited high toxicities when administered orally, dermally, or by the inhalation route. Three of the materials proved to be severely or extremely irritating to the eyes. The pilot dermal and teratogenesis studies revealed some evidence of decreased viability in offspring and reduced fetal body weights. The subcontract was terminated for convenience on June 9, 1978 when it became apparent that IBT could not satisfactorily continue the studies.

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Pages: 105

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NTIS, PC A06/MF A01.

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  • Other: DE82006943
  • Report No.: DOE/ET/10104-13
  • Grant Number: AC05-76ET10104
  • DOI: 10.2172/5605917 | External Link
  • Office of Scientific & Technical Information Report Number: 5605917
  • Archival Resource Key: ark:/67531/metadc1093235

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  • November 1, 1981

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  • Feb. 10, 2018, 10:06 p.m.

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Solvent-refined-coal (SRC) process: health programs. Research and development report No. 53, Interim report No. 39. Volume III. Pilot plant development work. Part 4: Industrial hygiene, clinical and toxicological programs. Final report of subcontract No. 10, June 1, 1976-June 9, 1978, report, November 1, 1981; United States. (digital.library.unt.edu/ark:/67531/metadc1093235/: accessed October 15, 2018), University of North Texas Libraries, Digital Library, digital.library.unt.edu; crediting UNT Libraries Government Documents Department.