Splenic sequestration of Tc-99m labeled heat treated red blood cells. [Feasibility of use for spleen imaging]

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The rate of blood clearance and spleen uptake as well as the total spleen uptake of heat damaged red blood cells labeled with Tc-99m was determined in eight patients, six of whom had chronic lymphatic leukemia, one had polycythemia vera and one had eosinophilia of unknown origin. Spleen uptake at 2 hrs was 72.0 +- 18.5%. Approximately 82.6% of the initial radioactivity was cleared from the blood by 2 hrs with a rapid T 1/2 component of 6.3 +- 4.7 min. The T 1/2 of splenic uptake was 8.3 +- 4.6 min with a plateauing of splenic radioactivity by 30 ... continued below

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Pages: 26

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Atkins, H L; Goldman, A G; Fairchild, R G; Oster, Z H; Som, P; Richards, P et al. January 1, 1979.

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Description

The rate of blood clearance and spleen uptake as well as the total spleen uptake of heat damaged red blood cells labeled with Tc-99m was determined in eight patients, six of whom had chronic lymphatic leukemia, one had polycythemia vera and one had eosinophilia of unknown origin. Spleen uptake at 2 hrs was 72.0 +- 18.5%. Approximately 82.6% of the initial radioactivity was cleared from the blood by 2 hrs with a rapid T 1/2 component of 6.3 +- 4.7 min. The T 1/2 of splenic uptake was 8.3 +- 4.6 min with a plateauing of splenic radioactivity by 30 min. The preliminary results indicate that the method of preparation is reliable but the usefulness of the method for evaluating spleen function remains to be determined.

Physical Description

Pages: 26

Notes

Dep. NTIS, PC A03/MF A01.

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  • 65. annual meeting of the Radiological Society of North America, Atlanta, GA, USA, 25 Nov 1979

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  • Report No.: BNL-27175
  • Report No.: CONF-791165-1
  • Grant Number: EY-76-C-02-0016
  • Office of Scientific & Technical Information Report Number: 5655847
  • Archival Resource Key: ark:/67531/metadc1093086

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Office of Scientific & Technical Information Technical Reports

Reports, articles and other documents harvested from the Office of Scientific and Technical Information.

Office of Scientific and Technical Information (OSTI) is the Department of Energy (DOE) office that collects, preserves, and disseminates DOE-sponsored research and development (R&D) results that are the outcomes of R&D projects or other funded activities at DOE labs and facilities nationwide and grantees at universities and other institutions.

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  • January 1, 1979

Added to The UNT Digital Library

  • Feb. 10, 2018, 10:06 p.m.

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  • April 16, 2018, 6:19 p.m.

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Atkins, H L; Goldman, A G; Fairchild, R G; Oster, Z H; Som, P; Richards, P et al. Splenic sequestration of Tc-99m labeled heat treated red blood cells. [Feasibility of use for spleen imaging], article, January 1, 1979; United States. (digital.library.unt.edu/ark:/67531/metadc1093086/: accessed October 17, 2018), University of North Texas Libraries, Digital Library, digital.library.unt.edu; crediting UNT Libraries Government Documents Department.