The glycophorin A assay for somatic cell mutations in humans

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Description

In this report we briefly review our past experience and some new developments with the GPA assay. Particular emphasis will be placed on two areas that affect the utility of the GPA assay for human population monitoring. The first is our efforts to simplify the GPA assay to make it more generally available for large population studies. The second is to begin to understand some of the characteristics of human hemopoiesis which affect the accumulation and expression of mutant phenotype cells. 11 refs., 4 figs.

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12 pages

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Langlois, R.G.; Bigbee, W.L. & Jensen, R.H. August 18, 1989.

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Description

In this report we briefly review our past experience and some new developments with the GPA assay. Particular emphasis will be placed on two areas that affect the utility of the GPA assay for human population monitoring. The first is our efforts to simplify the GPA assay to make it more generally available for large population studies. The second is to begin to understand some of the characteristics of human hemopoiesis which affect the accumulation and expression of mutant phenotype cells. 11 refs., 4 figs.

Physical Description

12 pages

Notes

NTIS, PC A03/MF A01; OSTI; INIS; GPO Dep.

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  • 5. international conference on environmental mutagens, Cleveland, OH (USA), 10-15 Jul 1989

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  • Other: DE90001652
  • Report No.: UCRL-101728
  • Report No.: CONF-8907113--12
  • Grant Number: W-7405-ENG-48
  • Office of Scientific & Technical Information Report Number: 5672697
  • Archival Resource Key: ark:/67531/metadc1086692

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Office of Scientific & Technical Information Technical Reports

Reports, articles and other documents harvested from the Office of Scientific and Technical Information.

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  • August 18, 1989

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  • Feb. 10, 2018, 10:06 p.m.

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  • Aug. 8, 2020, 5:51 p.m.

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Langlois, R.G.; Bigbee, W.L. & Jensen, R.H. The glycophorin A assay for somatic cell mutations in humans, article, August 18, 1989; [Livermore,] California. (https://digital.library.unt.edu/ark:/67531/metadc1086692/: accessed April 23, 2024), University of North Texas Libraries, UNT Digital Library, https://digital.library.unt.edu; crediting UNT Libraries Government Documents Department.

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