MULTIELEMENT ANALYSIS OF BIOLOGICAL MATERIAL BY NEUTRON ACTIVATION AND DIRECT INSTRUMENTAL TECHNIQUES. Page: 1 of 15
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THlE MULTILLEdENT ANALYSIS OF BIOLOGICAL MATERIAL
BY HEUThON ACTIVATION AND DIRECT INkSTRUTLIITAL TECHNIQUES (a)
Louis A. Rancitelli, Senior Research Scientist
John A. Cooper, Senior Research Scientist
Richard U. Perkins, Research Associate
Battelle Mnorial Institute, Pacific Northwest Laboratory
Richland, Uashington 99352 U.S.A.
Athou h several studios concerning the trace element concentrations
in biological organisms have been conducted over the years , the roles
of most trace elements in biological processes remain poorly understood.
This situation can, in part, be attributed to the lack of suitable
analytical technology which will permit precise multielement analysis
in the parts-per-million to sub-parts-per-billion range. Two analytical
techniques, cmrission spectroscopy , and. sparE source mass spectrom-
etry , have been shown to be capable of simultaneous multielement
analysis of biological material. However, these methods require ex-
tensive sample preparation with its associated contamination problems,
and are seriously limited in sensitivity for many trace constituents
by matrix effects and spectral interferences. The extension of trace
element measurements to permit an analysis of the fine structure of
the body organs and of cellular areas within the organs requires even
(a) This paper is based on work performed under Unites States Atomic
Energy Commission Contract AT(45-1)1830.
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use of any information, apparatus, method, or process disclosed in this report. M1STR'EUTION OF I1-jS DcrJ UM glgl 6 U ITfED
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Rancitelli, L.A.; Cooper, J.A. & Perkins, R.W. MULTIELEMENT ANALYSIS OF BIOLOGICAL MATERIAL BY NEUTRON ACTIVATION AND DIRECT INSTRUMENTAL TECHNIQUES., report, January 1, 1968; Richland, Washington. (https://digital.library.unt.edu/ark:/67531/metadc1033111/m1/1/: accessed April 18, 2019), University of North Texas Libraries, Digital Library, https://digital.library.unt.edu; crediting UNT Libraries Government Documents Department.