The Overpressure-Duration Relationship and Lethality in Small Animals. Technical Progress Report

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A total of 993 mice, rats, guinea pigs, and rabbits were exposed to sharp-rising overpressures of various short durations. They were mounted on a concrete pad above which high-explosive charges, ranging in weight from 0.50 oz to 64 lbs, were detonated. Pressure-time measurements were obtained with pencil- type and shock-tube piezo-electric gauges on the pad directly beneath the charges. The duration of the blast waves ranged from 0.40 to 6.8 msec. The LD/sub 50/ pressures were calculated for each species at the different pulse durations. In general, the pressures required to produce 50% lethality rose at the shorter durations. Combining … continued below

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56 pages

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Richmond, D. R.; Goldizen, V. C.; Clare, V. R. & White, C. S. September 10, 1962.

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A total of 993 mice, rats, guinea pigs, and rabbits were exposed to sharp-rising overpressures of various short durations. They were mounted on a concrete pad above which high-explosive charges, ranging in weight from 0.50 oz to 64 lbs, were detonated. Pressure-time measurements were obtained with pencil- type and shock-tube piezo-electric gauges on the pad directly beneath the charges. The duration of the blast waves ranged from 0.40 to 6.8 msec. The LD/sub 50/ pressures were calculated for each species at the different pulse durations. In general, the pressures required to produce 50% lethality rose at the shorter durations. Combining the results of this study with those from previous shock- tube investigations made it possible to define the tolerance of four small-animal species to sharply rising overpressures as a function of pulse duration. (auth)

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56 pages

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Other Information: Orig. Receipt Date: 31-DEC-63

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  • September 10, 1962

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Richmond, D. R.; Goldizen, V. C.; Clare, V. R. & White, C. S. The Overpressure-Duration Relationship and Lethality in Small Animals. Technical Progress Report, report, September 10, 1962; Albuquerque, New Mexico. (https://digital.library.unt.edu/ark:/67531/metadc1026074/: accessed January 20, 2026), University of North Texas Libraries, UNT Digital Library, https://digital.library.unt.edu; crediting UNT Libraries Government Documents Department.

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