Labeling of blood cells with /sup 99m/Tc

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Erythrocytes, leukocytes, and tumor cells were labeled with /sup 99m/Tc to take advantage of the ideal physical properties of /sup 99m/Tc. Clinical studies indicate that labeled erythrocytes can be used to obtain improved vascular and splenic imaging as well as reliable red cell volumes. The erythrocytes have been labeled with and without the use of an added reducing agent. Two methods of adding the reducing agent stannous chloride have been proposed which differ in the order of addition of the stannous ion and the pertechnetate. The preliminary reports of labeling of leukocytes and tumor cells offer hope that further development ... continued below

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Pages: 44

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Eckelman, W.C.; Smith, T.D. & Richards, P. January 1, 1974.

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Description

Erythrocytes, leukocytes, and tumor cells were labeled with /sup 99m/Tc to take advantage of the ideal physical properties of /sup 99m/Tc. Clinical studies indicate that labeled erythrocytes can be used to obtain improved vascular and splenic imaging as well as reliable red cell volumes. The erythrocytes have been labeled with and without the use of an added reducing agent. Two methods of adding the reducing agent stannous chloride have been proposed which differ in the order of addition of the stannous ion and the pertechnetate. The preliminary reports of labeling of leukocytes and tumor cells offer hope that further development will result in truly specific radiopharmaceuticals. (auth)

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Pages: 44

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Dep. NTIS

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  • International symposium on radiopharmaceuticals, Atlanta, Georgia, USA, 12 Feb 1974

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  • Report No.: BNL--18497
  • Report No.: CONF-740203--3
  • Grant Number: None
  • Office of Scientific & Technical Information Report Number: 4327933
  • Archival Resource Key: ark:/67531/metadc1024513

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Office of Scientific & Technical Information Technical Reports

Reports, articles and other documents harvested from the Office of Scientific and Technical Information.

Office of Scientific and Technical Information (OSTI) is the Department of Energy (DOE) office that collects, preserves, and disseminates DOE-sponsored research and development (R&D) results that are the outcomes of R&D projects or other funded activities at DOE labs and facilities nationwide and grantees at universities and other institutions.

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  • January 1, 1974

Added to The UNT Digital Library

  • Oct. 15, 2017, 10:09 p.m.

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  • Oct. 25, 2017, 10:18 p.m.

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Eckelman, W.C.; Smith, T.D. & Richards, P. Labeling of blood cells with /sup 99m/Tc, article, January 1, 1974; Upton, New York. (digital.library.unt.edu/ark:/67531/metadc1024513/: accessed November 23, 2017), University of North Texas Libraries, Digital Library, digital.library.unt.edu; crediting UNT Libraries Government Documents Department.