Enzymatic studies of radiation damage Metadata
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Title
- Main Title Enzymatic studies of radiation damage
Creator
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Author: Laskowski, M., Sr.Creator Type: Personal
Contributor
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Sponsor: U.S. Atomic Energy CommissionContributor Type: OrganizationContributor Info: AEC
Publisher
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Name: Roswell Park Memorial Inst., Buffalo, N.Y. (USA)Place of Publication: United States
Date
- Creation: 1974-01-01
Language
- English
Description
- Content Description: Progress is reported on studies related to molecular mechanisms for radiation damage to cells. Mung bean nuclease was shown to excise the A + T rich regions from different species of DNA exposed to premelting temperatures. This suggests an additional application of mung bean nuclease as a means of detection of slightly damaged reglons of DNA. A new sensitive method for the determination of nucleoside monophosphates and nucleoside 3', 5'-diphosphates was developed. The method was applied to the determination of the frequency of nucleosides appearing in the terminal position of an oligonucleotide. An argument serves biological unity of all nucaeases is presented. (auth)
- Physical Description: 10 pages
Subject
- Keyword: Nucleosides
- Keyword: Biological Radiation Effects
- Keyword: Plant Cells
- Keyword: Molecular Structure
- Keyword: Purification
- Keyword: Nucleotides
- Keyword: Animal Cells
- Keyword: N48200* --Life Sciences--Radiation Effects On Cells
- Keyword: *Radiation Injuries-- Molecular Biology
- Keyword: Biological Variability
- Keyword: Biochemical Reaction Kinetics
- Keyword: *Dna-- Radiation Injuries
- Keyword: Dna-Ase
Source
- Other Information: Orig. Receipt Date: 30-JUN-74
Collection
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Name: Office of Scientific & Technical Information Technical ReportsCode: OSTI
Institution
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Name: UNT Libraries Government Documents DepartmentCode: UNTGD
Resource Type
- Report
Format
- Text
Identifier
- Report No.: COO--3225-10
- Grant Number: AT(11-1)-3225
- DOI: 10.2172/4326357
- Office of Scientific & Technical Information Report Number: 4326357
- Archival Resource Key: ark:/67531/metadc1017341
Note
- Display Note: Dep. NTIS