Enzymatic studies of radiation damage Metadata

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Title

  • Main Title Enzymatic studies of radiation damage

Creator

  • Author: Laskowski, M., Sr.
    Creator Type: Personal

Contributor

  • Sponsor: U.S. Atomic Energy Commission
    Contributor Type: Organization
    Contributor Info: AEC

Publisher

  • Name: Roswell Park Memorial Inst., Buffalo, N.Y. (USA)
    Place of Publication: United States

Date

  • Creation: 1974-01-01

Language

  • English

Description

  • Content Description: Progress is reported on studies related to molecular mechanisms for radiation damage to cells. Mung bean nuclease was shown to excise the A + T rich regions from different species of DNA exposed to premelting temperatures. This suggests an additional application of mung bean nuclease as a means of detection of slightly damaged reglons of DNA. A new sensitive method for the determination of nucleoside monophosphates and nucleoside 3', 5'-diphosphates was developed. The method was applied to the determination of the frequency of nucleosides appearing in the terminal position of an oligonucleotide. An argument serves biological unity of all nucaeases is presented. (auth)
  • Physical Description: 10 pages

Subject

  • Keyword: Nucleosides
  • Keyword: Biological Radiation Effects
  • Keyword: Plant Cells
  • Keyword: Molecular Structure
  • Keyword: Purification
  • Keyword: Nucleotides
  • Keyword: Animal Cells
  • Keyword: N48200* --Life Sciences--Radiation Effects On Cells
  • Keyword: *Radiation Injuries-- Molecular Biology
  • Keyword: Biological Variability
  • Keyword: Biochemical Reaction Kinetics
  • Keyword: *Dna-- Radiation Injuries
  • Keyword: Dna-Ase

Source

  • Other Information: Orig. Receipt Date: 30-JUN-74

Collection

  • Name: Office of Scientific & Technical Information Technical Reports
    Code: OSTI

Institution

  • Name: UNT Libraries Government Documents Department
    Code: UNTGD

Resource Type

  • Report

Format

  • Text

Identifier

  • Report No.: COO--3225-10
  • Grant Number: AT(11-1)-3225
  • DOI: 10.2172/4326357
  • Office of Scientific & Technical Information Report Number: 4326357
  • Archival Resource Key: ark:/67531/metadc1017341

Note

  • Display Note: Dep. NTIS
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