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Studies of the status of antioxidant enzymes and metabolites following burn injury, and the presence of antioxidant enzymes in the Aloe vera plant

Description: The effects of skin burn injury on the levels of oxidized and reduced glutthione, malondialdehyde, and on the activities of glutathione peroxidase, glutathione S-transferase, and glutathione reductase were determined in liver and lung of rabbit models, 24-h post-burn.
Date: December 1995
Creator: Sabeh, Farideh
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries
open access

Effects of Cigarette Smoke Condensates on Cultured Human Lymphocytes and Separation of Benzo-α-Pyrene Metabolites by High Pressure Liquid Chromatography

Description: Cigarette smoke condensates from all cigarettes tested were found to be potent inducers of AHH enzyme in cultured human lymphocytes and, with the exception of Kent Lights and Carlton CSC's, all were found to be toxic under the experiment conditions. Most of the AHH inducing activity was found in basic and neutral fractions of the lAl standard cigarettes. A radiometric assay of BP metabolites in cultured human lymphocytes was developed in which we were able to separate the primary metabolites an… more
Date: August 1979
Creator: Ghanayem, Burhan I.
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries
open access

Chemical and Genetic Studies on the Formation of Pyrrolones During the Biosynthesis of Cytochalasans

Description: This article investigates the role of the highly conserved α,β-hydrolase enzymes PyiE and ORFZ during the biosynthesis of pyrichalasin H and the ACE1 metabolite, respectively, using gene knockout and complementation techniques. Taken together the results suggest that the α,β-hydrolase enzymes are essential for first ring cyclisation, but the precise nature of the intermediates remains to be determined.
Date: November 4, 2020
Creator: Zhang, Haili; Hantke, Verena; Bruhnke, Pia; Skellam, Elizabeth & Cox, Russell J.
Item Type: Refine your search to only Article
Partner: UNT College of Science
open access

Application of Novel Microporous Polyolefin Silica-Based Substrate in Paper Spray Mass Spectrometry (PS-MS)

Description: This study addressed five key applications of paper spray mass spectrometry (PS-MS): (i) comparative analysis of the microporous substrate with the cellulose-based substrate in drug detection; (ii) detection of more than 190 fentanyl analogs with their fragmentation pattern can be implemented in the future reference for quicker, accurate and sensitive determination; (iii) exploring sweat in a fingerprint to be considered an alternate method to recognize non-invasive markers of metabolites, lip… more
Date: December 2020
Creator: Weligamage De Silva, Imesha
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries
open access

Functional Characterization of Proanthocyanidin Pathway Enzymes from Tea and Their Application for Metabolic Engineering

Description: Article on the functional characterization of proanthocyanidin pathway enzymes from tea and their application for metabolic engineering.
Date: March 2013
Creator: Pang, Yongzhen; Abeysinghe, I. Sarath B.; He, Ji; He, Xian-Zhi; Huhman, David; Mewan, K. Mudith et al.
Item Type: Refine your search to only Article
Partner: UNT College of Arts and Sciences
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