Hepatotoxicity of Mercury to Fish

Hepatotoxicity of Mercury to Fish

Date: August 2010
Creator: Barst, Benjamin Daniel
Description: Tissue samples from spotted gar (Lepisosteus oculatus) and largemouth bass (Micropterus salmoides) were collected from Caddo Lake. Gar and bass livers were subjected to histological investigation and color analysis. Liver color (as abs at 400 nm) was significantly correlated with total mercury in the liver (r2 = 0.57, p = 0.02) and muscle (r2 = 0.58, p = 0.01) of gar. Evidence of liver damage as lipofuscin and discoloration was found in both species but only correlated with liver mercury concentration in spotted gar. Inorganic mercury was the predominant form in gar livers. In order to determine the role of mercury speciation in fish liver damage, a laboratory feeding study was employed. Zebrafish (Danio rerio) were fed either a control (0.12 ± 0.002 µg Hg.g-1 dry wt), inorganic mercury (5.03 ± 0.309 µg Hg.g-1 dry wt), or methylmercury (4.11 ± 0.146 µg Hg.g-1 dry wt) diet. After 78 days of feeding, total mercury was highest in the carcass of zebrafish fed methylmercury (12.49 ± 0.369 µg Hg.g-1 dry wt), intermediate in those fed inorganic mercury (1.09 ± 0.117 µg Hg.g-1 dry wt), and lowest in fish fed the control diet (0.48 ± 0.038 µg Hg.g-1 dry wt). Total mercury was ...
Contributing Partner: UNT Libraries
Recovery of the Fish Population of a Municipal Wastewater Dominated, North Texas Creek after a Major Chlorine Disturbance

Recovery of the Fish Population of a Municipal Wastewater Dominated, North Texas Creek after a Major Chlorine Disturbance

Date: August 2002
Creator: Maschmann, Gerald F.
Description: This study evaluated the effects of a major chlorine disturbance on fish communities in Pecan creek by the City of Denton's Pecan Creek Water Reclamation Plant. Fish communities in Pecan Creek were sampled using a depletion methodology during February, April, July, and November, 1999. February and April sampling events showed that the fish communities were severely impacted by the chlorine. Sampling during July and November showed fish communities recovered in Pecan Creek. The first-twenty minutes of shocking and seining data were analyzed to mirror an equal effort methodology. This methodology was compared to the depletion methodology to see if the equal effort methodology could adequately monitor the recovery of Pecan Creek after the chlorine disturbance. It was determined that the equal effort methodology was capable of monitoring the recovery of Pecan Creek, but could not accurately represent the fisheries community as well as the depletion method. These data using the twenty-minute study were compared to a previous study. Results of this study were similar to those found in a previous study, although fish communities were more severely impacted and took longer to recover.
Contributing Partner: UNT Libraries
The Food and Growth of the Largemouthed Black Bass (Huro Salmoides) in North Texas

The Food and Growth of the Largemouthed Black Bass (Huro Salmoides) in North Texas

Date: August 1939
Creator: Hill, Jackson F.
Description: This thesis describes the growth and feeding habits of large mouth bass (Huro salmoides) as observed in North Texas.
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The Effects of Changes in Hydrostatic Pressure on Some Hudson River Biota: Progress Report for 1974

The Effects of Changes in Hydrostatic Pressure on Some Hudson River Biota: Progress Report for 1974

Date: September 1974
Creator: New York University. Medical Center. Institute of Environmental Medicine.
Description: This research report represents the findings on a study conducted over the effect of hydrostatic pressure and hydroelectric generators on various types of fish and other aquatic organisms in the Hudson River.
Contributing Partner: UNT Libraries
Ecological Studies of the Hudson River Near Indian Point

Ecological Studies of the Hudson River Near Indian Point

Date: April 1971
Creator: New York University. Medical Center. Institute of Environmental Medicine.
Description: "The general purpose of [this study is] to determine the ecological responses of the [Hudson] River to various classes of potential pollutants, so that the discharge of waste heat and radionuclides from the Indian Point Power Plant can be evaluated in context with these" (p. 1).
Contributing Partner: UNT Libraries
Effects of Entrainment by the Indian Point Power Plant on Biota in the Hudson River Estuary, 1973

Effects of Entrainment by the Indian Point Power Plant on Biota in the Hudson River Estuary, 1973

Date: September 1974
Creator: New York University. Medical Center. Institute of Environmental Medicine.
Description: "This report summarizes the progress of studies conducted in 1973 to determine the effects on Hudson River organisms of entrainment by the Indian Point nuclear power station" with emphasis "on the potential effects of entrainment on organisms passing through the plant's condenser cooling system" (p. xxi).
Contributing Partner: UNT Institute of Applied Sciences
Effects of Entrainment by the Indian Point Power Plant on Biota in the Hudson River Estuary, March 1975

Effects of Entrainment by the Indian Point Power Plant on Biota in the Hudson River Estuary, March 1975

Date: March 1975
Creator: New York University. Medical Center. Institute of Environmental Medicine.
Description: "The data presented in this report represent an analysis of the abundance of four life-history stages of striped bass collected in the Hudson River at Indian Point and the intakes and discharge canal at the Indian Point Power Station" (p. 54).
Contributing Partner: UNT Libraries
Distribution, Size, Condition, and Food Habits of Selected Fishes in a Reservoir Receiving Heated Effluent from a Power Plant

Distribution, Size, Condition, and Food Habits of Selected Fishes in a Reservoir Receiving Heated Effluent from a Power Plant

Date: December 1972
Creator: McNeely, David L.
Description: This study was undertaken in order to provide further insight into the effects of artificial heating on the fisheries of a small reservoir in the Southwest. The following specific objectives were established: (1) to map the reservoir for the distribution of heated water, (2) to determine the distribution of selected species of sports, rough, and forage fish in areas affected by the effluent and in areas not affected, (3) to compare size and condition of selected species of fish from areas affected by the effluent to size and condition of fish from areas not affected, and (4) to compare food habits of channel catfish in areas affected by the effluent to the food habits of channel catfish in areas not affected.
Contributing Partner: UNT Libraries
Endocrine Disruption of Levonorgestrel in Early-life Stages of Fathead Minnows, Pimephales Promelas

Endocrine Disruption of Levonorgestrel in Early-life Stages of Fathead Minnows, Pimephales Promelas

Date: August 2013
Creator: Overturf, Matthew D.
Description: Pharmaceuticals have routinely been detected in the environment resulting in a growing concern about whether these drugs could elicit effects on aquatic organisms. The concerns are centered on the highly conserved nature of mammalian therapeutic targets in fish. These pharmaceuticals are found at very low levels in the environment, which can result in sub-lethal effects in aquatic organisms. Therefore, 28 d early-life stage studies were conducted on six pharmaceuticals to assess their impacts on survival and growth fathead minnow larvae. Two pharmaceuticals tested, carbamazepine and fenofibrate, resulted in no alterations to survival and growth. However, amiodarone, clozapine, dexamethasone, and levonorgestrel (LNG) reduced survival at concentrations tested with LNG being the most potent at 462 ng/L. Survival was increased with amiodarone and clozapine; however LNG significantly decreased growth at 86 ng/L. Therefore, the most potent pharmaceutical tested was the synthetic progestin LNG with survival and growth impacts at concentrations less than 1 μg/L. Further analysis was conducted by measuring specific endocrine related mRNA transcript profiles in FHM larvae following the 28 d ELS exposure to LNG. Transcripts of 3β-HSD, 20β-HSD, and FSH were significantly down-regulated following 28 d exposure to both 16.3 and 86.9 ng/L LNG. Also, CYP19a expression was significantly ...
Contributing Partner: UNT Libraries
The Response of Amphibia and Rodents to Fish Gonadotropins

The Response of Amphibia and Rodents to Fish Gonadotropins

Date: 1949
Creator: Bishop, Jack G.
Description: The purpose of this research is, first, to determine by laboratory methods, that species specificity does not exist in closely allied taxonomic animals; second, to determine a unit of activity for the gonadotropic hormone. For this purpose a quantitative method for determining potency is necessary to ascertain the seasonal production of the gonadotropic factor in fish. A further aim in this investigation is to demonstrate that the diversity of the gonadotropic factor, in relation to phylogenetic variations, is not as ineffectual as previously reported.
Contributing Partner: UNT Libraries
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