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The anti-apoptotic proteins NAF-1 and iASPP interact to drive apoptosis in cancer cells
This article reveals an interaction between the two anti-apoptotic proteins iASPP and NAF-1, which are overexpressed in many types of cancer cells and tumors.
Biocompatible Graphene-based Growth of Cancer Cells: A Work in Progress
Poster presentation for the 2012 University Scholars Day at the University of North Texas. This poster discusses research on the biocompatible graphene-based growth of cancer cells. Graphene is made of a single layer of carbon atoms. Recently is has been used to successfully differentiate stem cells in neural cells.
Nanoparticles & Cancer Cells
Undergraduate research thesis studying nanoparticles as a therapeutic approach in cancer-targeting drugs and their effects on mammals. The author hypothesizes that nanoparticles can make cancer-targeting drugs more effective. This thesis also includes the PowerPoint slides presented at UNT Scholar's Day.
Observations on Nuclear RNA During Mitosis in Human Cancer Cells in Culture (HeLa-S₃), Studied with Tritiated Cytidine
Observations on nuclear RNA labeled with H³-cytidine, by autoradiography in the HeLa-S₃ cells in interphase and in mitosis led to the following conclusions: 1) RNA synthesis continues in cells in mitosis until late prophase. Most of the labeled RNA in prophase is associated with the chromosomes, and more with the chromosomal surface than the core. Nucleolar labeling amounts to less than 16%. The degree and the pattern of nuclear labeling is similar in early prophase and in interphase. This indicates that in the HeLa cell the synthesis of more than 80% of the RNA occurs on chromosomes. 2) With progression of the labeled cells through the stages of mitosis, the labeling associated with the chromosomes contributes to cytoplasmic RNA. Approximately one-fourth of the label remains associated with the chromosomes even through anaphase. There is no indication that this persistent chromosomal labeled RNA contributes to the organization of the nucleoli at telophase. 3) RNA synthesis resumes at telophase within the chromatin portion of the nuclei. Nucleotides for the resuming RNA synthesis are derived at least in part from the acid-soluble fraction of the cell, where they had remained throughout mitosis without exchange with non-labeled nucleoside in the extracellular medium.
[News Clip: Harold Part 9]
Video footage from the KXAS-TV/NBC station in Fort Worth, Texas, to accompany a news story.
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