Aging Is a Determinant in Anoxia Stress Tolerance in Caenorhabditis Elegans

Aging Is a Determinant in Anoxia Stress Tolerance in Caenorhabditis Elegans

Date: May 2013
Creator: Goy, Jo M.
Description: Oxygen availability is critical for survival for most organisms. The nematode, C. elegans, has been useful for studying genetic regulation of anoxia tolerance due to the oxygen deprivation response mechanisms shared with other metazoans. Studies examining long-term anoxia (72h, LTA) tolerance have only been conducted at adult day 1. To investigate the effect of aging on anoxia tolerance wild-type and mutant strains were exposed to LTA between adult day 1 and day 9. Wild-type isolates and daf-16(mu86) (FOXO transcription factor regulated by insulin-signaling) and aak-2(gt33) (catalytic subunit of AMP-activated protein kinase) strains were anoxia sensitive at day 1 and displayed increased LTA tolerance with aging correlated with reproductive senescence followed by a decline in survivorhsip through day 9. The daf-2(e1370) (insulin receptor homologue of C. elegans), glp-1(e2141) (a lin-12/Notch receptor) and fog-2(q71) (required for spermatogenesis) strains were LTA-tolerant through day 5. I conclude that aging influences LTA-tolerance in a strain- and age-dependent manner. In addition to being LTA-tolerant the daf-2(e1370) and glp-1(e2141) strains have a longevity phenotype that is suppressed by loss of kri-1 or daf-12. While loss of kri-1 did not suppress the LTA-tolerant phenotype of glp-1(e2141) at day 1 the portion of impaired survivors increased at day 3 ...
Contributing Partner: UNT Libraries
Determinants of the Applications to the Institutional Care in Turkey: Darulaceze Example

Determinants of the Applications to the Institutional Care in Turkey: Darulaceze Example

Date: May 2013
Creator: Esendemir, Serif
Description: Although institutional care has started to be outmoded in the developed countries with development of different models of care, it still has a considerable place in the developing countries such as Turkey. This is because, changes in the demographic structure, extended family, and urban development of Turkey has brought about several aging problems leading older adults to end up in institutions. Loneliness was one of the significant reasons given in the Social Inquiry Survey of Applicants of Darulaceze Old-Age Institution and the basis for a micro level analysis in this study. Therefore, the main objective of the study was to determine the predictors of loneliness, including age, the state of living alone, functional independence, education, and gender. Analysis of the results indicated that these predictors have significant effects on the loneliness predominantly defined by social factors rather than medical factors. In addition, the meso and macro level analyses were employed to control the micro level analysis and see a general picture of institutional care. Thus, an academic example of diagnosing the main reasons behind the institutional care was presented to understand the context of aging in Turkey.
Contributing Partner: UNT Libraries
The Journal for Vocational Special Needs Education

The Journal for Vocational Special Needs Education

Date: 1998
Creator: Allen, Jeff M.; Sarkees-Wircenski, Michelle & West, Lynda L.
Description: This issue of the Journal for Vocational Special Needs focuses on the aging process and its effects on society and the workforce. Aging is the one experience that we all have in common. Individuals are expected to live longer in the future. Many will undoubtedly work beyond the traditional retirement age. This means that the composition of workers will be a blend of people, both young and old.
Contributing Partner: UNT College of Information
ReSource, Volume 11, Number 1, Fall 1994

ReSource, Volume 11, Number 1, Fall 1994

Date: 1994
Creator: University of North Texas
Description: ReSource magazine includes articles and notes about research at University of North Texas in various academic fields.
Contributing Partner: University Relations, Communications & Marketing department for UNT
Contributions of Early Amerian Sociologists to Social Gerontology

Contributions of Early Amerian Sociologists to Social Gerontology

Date: August 1965
Creator: Teague, Richard L.
Description: The purpose of this thesis is to explore the writings of early American sociologists for attitudes and theoretical ideas concerning aging which individually and collectively have formed the basis for current social theory in gerontology.
Contributing Partner: UNT Libraries
Evaluation of Adjustment Criteria in Institutions for the Aged

Evaluation of Adjustment Criteria in Institutions for the Aged

Date: August 1964
Creator: Wolford, Lenore L.
Description: This thesis focuses on the question of how the elderly adjust to changed living conditions. This question is vitally important, not only to the older person but also to their relatives.
Contributing Partner: UNT Libraries
Financing Geriatric Programs in Community Health Centers

Financing Geriatric Programs in Community Health Centers

Date: 1991
Creator: Yeatts, Dale E., 1952-; Ray, Sheila; List, Noel & Duggar, Benjamin
Description: Article on financing geriatric programs in community health centers.
Contributing Partner: UNT College of Public Affairs and Community Service
Comparative Models of the Impact of Social Support on Psychological Distress in Cancer Patients

Comparative Models of the Impact of Social Support on Psychological Distress in Cancer Patients

Date: May 2000
Creator: Forjaz, Maria João Bettencourt Pereira
Description: This study tested the relationship between Social Support, Psychological Distress, and Illness Stress in individuals who report cancer as a health condition. This study was based on archival data obtained from the Wave 1 of the Health and Retirement Study (HRS). The HRS provides a nationally representative sample of individuals aged 51 to 61 in 1992 and their spouses. The study sample was limited to cancer patients with a spouse or partner (n = 503). A structural equation modeling analysis procedure was used to test the theoretical models. Measures of social support were limited to variables assessing the participant's satisfaction with social support. Evidence was found for the Stress Prevention and the Support Deterioration models. This is congruent with previous research using measures of social support perception. Both the Stress Prevention and the Support Deterioration models predict a negative relationship between Illness Stress and Social Support. In addition, a univariate analysis of variance was used to test the stress buffering model. Similarly to other studies measuring the individual's degree of integration, or its perception, in the social network, the present research supported the only the Main Effect model and not the Stress Buffering model.
Contributing Partner: UNT Libraries
The Willingness of Older Adults to Evacuate in the Event of a Disaster

The Willingness of Older Adults to Evacuate in the Event of a Disaster

Date: May 2009
Creator: Gray-Graves, Amy Michael
Description: The issue of rising number of disasters, the overwhelming increase in number of older adults, and historically flawed evacuations presents real challenges. Disasters can strike anywhere, any time, and have devastating consequences. Since 1900, the number of Americans 65 and older has increased 12 times (from 3.1 million to 36.3 million). During the next two decades, the number of American baby boomers, now aged 45-64, who turn 65, will increase by 40%. As evidenced by recent disasters, the imperfections and vulnerabilities of flawed evacuations for older adults are still present. This study examined the level of willingness to evacuate among older adults in the event of a disaster. Despite the extensive literature on disasters and evacuation, some significant questions regarding evacuation and older adults have not been addressed. This study addressed the following concerns: (1) What is the willingness among older adults to evacuate when asked to do so by emergency management officials? (2) Does the call to evacuate being mandatory versus voluntary influence the willingness of seniors to evacuate? (3) Do preconditions (Gender, Marital Status, Age, Ethnic Origin, and Education Levels) influence the willingness to evacuate among older adults? The sample population consisted of 765 voluntary participants aged 60 ...
Contributing Partner: UNT Libraries
A Study of the Aging Process

A Study of the Aging Process

Date: April 15, 2010
Creator: Roman, Jorge & Dzialowski, Edward M. (Edward Michael)
Description: This poster discusses a research study on the theories as to why the biological process of aging takes place.
Contributing Partner: UNT Honors College
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