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open access

Tissue architecture and breast cancer: the role of extracellular matrix and steroid hormones

Description: The changes in tissue architecture that accompany the development of breast cancer have been the focus of investigations aimed at developing new cancer therapeutics. As we learn more about the normal mammary gland, we have begun to understand the complex signaling pathways underlying the dramatic shifts in the structure and function of breast tissue. Integrin-, growth factor-, and steroid hormone-signaling pathways all play an important part in maintaining tissue architecture; disruption of the… more
Date: June 1, 2000
Creator: Hansen, R K & Bissell, M J
Partner: UNT Libraries Government Documents Department
open access

Seasonal Patterns of Melatonin, Cortisol, and Progesterone Secretion in Female Lambs Raised Beneath a 500-kV Transmission Line.

Description: Although several kinds of biological effects of electric and magnetic fields have been reported from laboratory studies, few have been independently replicated. When this study was being planned, the suppression of nighttime melatonin in rodents was thought to represent one of the strongest known effects of these fields. The effect had been replicated by a single laboratory for 60-Hz electric fields, and by multiple laboratories for d-c magnetic fields. The primary objective of this study was t… more
Date: June 1, 1992
Creator: Lee, Jack M.
Partner: UNT Libraries Government Documents Department
open access

International Convention Against Doping in Sport: Issues for Congress

Description: The International Convention Against Doping in Sport seeks to harmonize anti-doping commitments for non-professional sports at the international level. Issues that could arise as the Senate considers the Convention include its relationship to anti-doping regulations in professional sports, potential consequences that non-ratification could pose to the United States, and the legitimacy and effectiveness of current international anti-doping activities.
Date: June 26, 2008
Creator: Wyler, Liana Sun
Partner: UNT Libraries Government Documents Department
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