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open access

Theranostic Small-Molecule Prodrug Conjugates for Targeted Delivery and Controlled Release of Toll-like Receptor 7 Agonists

Description: This article presents a novel class of chemically identical theranostic small-molecule prodrug conjugates (T-SMPDCs), [¹⁸/¹⁹F]F-TZ(PSMA)-LEGU-TLR7, for PSMA-targeted delivery and controlled release of toll-like receptor 7 (TLR7) agonists to elicit de novo immune response for cancer immunotherapy. The proof-of-concept biological evaluation presented demonstrates the potential of T-SMPDCs for cancer immunomodulatory therapies.
Date: June 28, 2022
Creator: Debnath, Sashi; Hao, Guiyang; Guan, Bing; Thapa, Pawan; Hao, Justin; Hammers, Hans et al.
Partner: Texas Academy of Mathematics and Science

The correlation-consistent composite approach: Implementation of the resolution-of-the-identity approximation

Description: Presentation for the 2009 University Scholars Day at the University of North Texas discussing research on the correlation-consistent composite approach (ccCA) and implementation of the resolution-of-the-identity approximation.
Date: April 2, 2009
Creator: Lai, Jeremy; Wilson, Angela K. & Prascher, Brian
Partner: UNT Honors College
open access

Retreating Glaciers of the Himalayas: A Case Study of Gangotri Glacier Using 1990-2009 Satellite Images

Description: This paper discusses research on the spatial and temporal variation of the Gangotri Glacier, one of the largest glaciers in the Himalayas. The authors discuss how this influences the River Ganges and, consequently, the people of the Indian subcontinent.
Date: April 1, 2010
Creator: Ding, Jennifer & Dong, Pinliang
Partner: UNT Honors College
open access

Use of tree-based models to identify subgroups and increase power to detect linkage to cardiovascular disease traits

Description: This article discusses the use of tree-based models to identify subgroups and increase power to detect linkage to cardiovascular disease traits.
Date: December 31, 2003
Creator: Costello, Tracy Jennifer; Swartz, Michael D.; Sabripour, Mahyar; Gu, Xiangjun; Sharma, Rishika & Etzel, Carol J.
Partner: UNT College of Arts and Sciences
open access

Relative Rate and Product Studies of the Reactions of Atomic Chlorine With Tetrafluoroethylene, 1,2-Dichloro-1,2-Difluoroethylene, 1,1-Dichloro-2,2-Difluoroethylene, and Hexafluoro-1,3-Butadiene in the Presence of Oxygen

Description: This article assesses rates of reactions in the context of atmospheric chemistry.
Date: August 31, 2016
Creator: Herath, Thushani N.; Clinch, Eric C.; Orozco, Ivan; Raign, Erin L. & Marshall, Paul
Partner: UNT College of Arts and Sciences
open access

Bioengineering Systems for Modulating Notch Signaling in Cardiovascular Development, Disease, and Regeneration

Description: This article is a review summarizing the significant roles of Notch signaling in individual cardiac cell types. It covers the bioengineering systems of microfluidics, hydrogel, spheroid, and 3D bioprinting and provides insights into ancillary supports of bioengineering systems, varied types of cardiovascular cells, and advanced characterization approaches in further refining Notch signaling in cardiovascular development, disease, and regeneration.
Date: September 30, 2021
Creator: Huerta Gomez, Angello; Joshi, Sanika; Yang, Yong; Tune, Johnathan D. & Zhao, Ming-Tao
Partner: University of North Texas
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