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Polysaccharides and bacterial plugging

Description: Before any successful application of Microbial Enhanced Oil Recovery process can be realized, an understanding of the cells' transport and retentive mechanisms in porous media is needed. Cell transport differs from particle transport in their ability to produce polysaccharides, which are used by cells to adhere to surfaces. Cell injection experiments have been conducted using Leuconostoc cells to illustrate the importance of cellular polysaccharide production as a transport mechanism that hinde… more
Date: November 1, 1991
Creator: Fogler, H. S.
Partner: UNT Libraries Government Documents Department
open access

Kinetic analysis of dynamic PET data

Description: Our goal is to quantify regional physiological processes such as blood flow and metabolism by means of tracer kinetic modeling and positron emission tomography (PET). Compartmental models are one way of characterizing the behavior of tracers in physiological systems. This paper describes a general method of estimating compartmental model rate constants from measurements of the concentration of tracers in blood and tissue, taken at multiple time intervals. A computer program which applies the me… more
Date: December 1, 1983
Creator: Knittel, B.
Partner: UNT Libraries Government Documents Department
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Preferred methods of analysis for chemical tracers in moderate- and high-temperature geothermal environments

Description: This report describes the sampling and analytical techniques used for tracer analysis in the Raft River and East Mesa field tests. The collection procedures and sample preservation techniques, analytical methods and possible sources of contamination or error are discussed in detail. 6 refs.
Date: December 1, 1984
Creator: Kroneman, R.L.; Yorgason, K.R. & Moore, J.N.
Partner: UNT Libraries Government Documents Department
open access

Gelled polymer systems for permeability modification in petroleum reservoirs

Description: The research program described in this report was conducted to improve the performance and predictability of in situ gelation processes designed to increase volumetric sweep efficiency of fluid displacement processes. A principal objective of this research was to develop procedures for design and evaluation of permeability modification processes. Research was conducted in three broad areas: (1) Physical and Chemical Characterization of Gelling Systems (2) In situ Gelation and (3) Mathematical M… more
Date: September 1, 1991
Creator: Willhite, G.P.; Green, D.W.; Thiele, J.L.; McCool, C.S. & Mertes, K.B.
Partner: UNT Libraries Government Documents Department
open access

Three year progress report and renewal request

Description: A review of research accomplisments during the contract period is presented. Reported projects include: (1) metals as radiation sensitizers of spores; (2) studies on transforming and calf thymus DNA; (3) pulse radiolysis studies on DNA components; (4) studies of metal complexes of DNA compounds; and (5) dosimetry of the pulsed electron beam. (ACR)
Date: August 1, 1980
Creator: Powers, E. L.
Partner: UNT Libraries Government Documents Department
open access

Interdisciplinary research and training program in the plant sciences

Description: This document is the compiled progress reports from the Interdisciplinary Research and Training Program in the Plant Sciences funded through the MSU-DOE Plant Research Laboratory. Fourteen reports are included, covering topics such as the molecular basis of plant/microbe symbiosis, cell wall proteins and assembly, gene expression, stress responses, growth regulator biosynthesis, interaction between nuclear and organelle genomes, sensory transduction and tropisms, intracellular sorting and membr… more
Date: January 1, 1991
Creator: Wolk, C.P.
Partner: UNT Libraries Government Documents Department
open access

Harvard-MIT research program in short-lived radiopharmaceuticals

Description: This report presents research on radiopharmaceuticals. The following topics are discussed: antibody labeling with positron-emitting radionuclides; antibody modification for radioimmune imaging; labeling antibodies; evaluation of technetium acetlyacetonates as potential cerebral blood flow agents; and studies in technetium chemistry. (CBS)
Date: January 1, 1991
Creator: Adelstein, S.J.
Partner: UNT Libraries Government Documents Department
open access

Nuclear medicine program progress report for quarter ending December 31, 1991

Description: This report presents information on (1) a new improved synthesis of carrier-free rhenium-188-labeled Re(V) dimercaptosuccinic acid (DMSA) complex as a potential therapeutic agent for treatment of thyroid medullary carcinoma; and (2) the synthesis and evaluation of a series of iodine-125-labeled analogues of altanserine for imaging of serotonin receptors.
Date: April 1, 1992
Creator: Knapp, F. F., Jr.; Ambrose, K. R.; Callahan, A. P.; McPherson, D. W.; Mirzadeh, S.; Srivastava, P. C. et al.
Partner: UNT Libraries Government Documents Department
open access

Synthetic inactivators of kallikrein

Description: Reagents were developed which bind covalently to side chains of kallikrein, thereby inactivating the enzyme. Both temporary and irreversible inhibitors have been synthesized. (ACR)
Date: January 1, 1981
Creator: Shaw, E.
Partner: UNT Libraries Government Documents Department
open access

Some nitrogen-14 NMR studies in solids

Description: The first order quadrupolar perturbation of the /sup 14/N NMR spectrum yields information regarding the static and dynamic properties of the surrounding electronic environment. Signal to noise problems caused by long /sup 14/N longitudinal relaxation times (T/sub 1/) and small equilibrium polarizations are reduced by rotating frame cross polarization (CP) experiments between /sup 14/N and /sup 1/H. Using quadrupolar echo and CP techniques, the /sup 14/N quadrupolar coupling constants (e/sup 2/q… more
Date: November 1, 1983
Creator: Pratum, T. K.
Partner: UNT Libraries Government Documents Department
open access

(Radiopharmacokinetics: Utilization of nuclear medicine)

Description: The work performed in the 1986/1989 period can be characterized as one of testing and documenting that the Radiopharmacokinetic technique is both feasible and applicable to human studies, as well as developing spectroscopic methods for undertaking noninvasive human studies. Main accomplishments include studies which: show that drug targeting can be monitored noninvasively using radiolabeled drugs. The study that documented this finding involved an analysis of the comparative kinetics of biodist… more
Date: January 1, 1989
Creator: Wolf, W.
Partner: UNT Libraries Government Documents Department
open access

Radioprotective drugs: a synopsis of current research and a proposed research plan for the Federal Emergency Management Agency. Final report

Description: FEMA has broad roles in the management of disasters potentially involving substantial amounts of radioactive contamination. These could be either peacetime or wartime disasters. A meeting was held in March 1985 to see if there are any research contributions that FEMA might reasonably make in the area of radioprotective drugs that would substantially enhance its ability to perform its mission. The other federal agencies presently sponsoring research in the field were represented at the meeting. … more
Date: April 1, 1985
Creator: Hickman, R. & Anspaugh, L.
Partner: UNT Libraries Government Documents Department
open access

Development and radiotherapeutic application of /sup 211/At-labeled radiopharmaceuticals. Progress report, March 1, 1981-February 28, 1982

Description: This project is concerned with developing the potential of alpha-emitting radionuclides as agents for radiotherapy. Alpha-emitters seem ideally suited for his application because their high linear energy transfer and short range permit the deposition of considerable energy in a very small volume of tissue. Unlike the beta particles of /sup 131/I which have a range of about 1 to 2 mm in tissue, 5 to 7 MeV alpha particles would traverse only a few cell diameters. Among the available alpha-emitter… more
Date: January 1, 1981
Creator: Adelstein, S.J.; Zalutsky, M. & Bloomer, W.
Partner: UNT Libraries Government Documents Department
open access

Recovery of anaerobic digestion after exposure to toxicants. Final report

Description: The concept that methane fermentation cannot tolerate chronic or slug doses of toxicants has almost totally precluded methane fermentation as a viable contender for the treatment of industrial wastewaters. This study assayed a wide variety of toxicants, heavy metals, inorganic salts, organic chemicals, solvents, and antibiotics which are used in industrial processes and, therefore, appear in the industrial wastewaters therefrom. Toxicity was related to the reduction in methane production of a c… more
Date: December 1, 1979
Creator: Yang, J.; Parkin, G. F. & Speece, R. E.
Partner: UNT Libraries Government Documents Department
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Implementation of the GAUSSIAN 78 programs on the NYU VAX/11-780: a probe into basis set and correlation effects on the structure of molecular complexes. [Complexes of p- and m-hydroxylaniline with formamidinium cation]

Description: The program package is used in a theoretical study of molecular complexes that serve as models of drug receptor interactions. The complexes are of para-hydroxyaniline and meta-hydroxyaniline with formamidinium cation. Results indicate that the description of the nature of interaction obtained at the STO-3G SCF level does not change when the basis set is extended to the 4-31G level or when correlation effects are included to second order in a Moeller-Plesset formulation. 5 figures, 4 tables. (DL… more
Date: April 1, 1980
Creator: Topiol, S; Moskowitz, J W; Osman, R & Weinstein, H
Partner: UNT Libraries Government Documents Department
open access

Quantitative mammalian cell genetic toxicology: study of the cytotoxicity and mutagenicity of 70 individual environmental agents related to energy technologies and 3 subfractions of a crude synthetic oil in the CHO/HGPRT system. [Hamsters]

Description: Conditions necessary for quantifying mutation-induction to 6-thioguanine resistance, which selects for >98% mutants deficient in the activity of hypoxanthine-guanine phosphoribosyl transferase (HGPRT) in a near-diploid Chinese hamster ovary (CHO) cell line, referred to as CHO/HGPRT system, have been defined. Employing this mutation assay, we have determined the mutagenicity of diversified agents including 11 direct-acting alkylating agents, 16 nitrosamines, 10 heterocyclic nitrogen mustards,… more
Date: January 1, 1978
Creator: Hsie, A. W.; Neill, J. P. & San Sebastian, J. R.
Partner: UNT Libraries Government Documents Department
open access

Noninvasive measurement of regional myocardial glucose metabolism by positron emission computed tomography. [Dogs]

Description: While the results of regional myocardial glucose metabolism measurements using positron emission computed tomography (/sup 13/N-ammonia) are promising, their utility and value remains to be determined in man. If this technique can be applied to patients with acute myocardial ischemia or infarction it may permit delineation of regional myocardial segments with altered, yet still active metabolism. Further, it may become possible to evaluate the effects of interventions designed to salvage revers… more
Date: June 1, 1980
Creator: Schelbert, H. R. & Phelps, M. E.
Partner: UNT Libraries Government Documents Department
open access

FDA Approved Registration of Erythromycin for Treatment of Bacterial Kidney Disease (BKD) in Juvenile and Adult Chinook Salmon : Annual Report, Reporting Period March 10, 1989 to March 9, 1990.

Description: Erythromycin is a therapeutic substance useful against bacterial kidney disease in salmon. In 1989 we began a multi year project to learn more about erythromycin applied to juvenile and adult salmon, with the goal of achieving registration of erythromycin with the US Food and Drug Administration. To begin the study, we studied the pharmacokinetics of erythromycin administered to both adult and juvenile chinook salmon. We monitored blood plasmas time curves from individual adult fish injected wi… more
Date: April 1, 1991
Creator: Moffitt, Christine A.
Partner: UNT Libraries Government Documents Department
open access

Synthesis of carbon-11, fluorine-18, and nitrogen-13 labeled radiotracers for biomedical applications

Description: A number of reviews, many of them recent, have appeared on various aspects of /sup 11/C, /sup 18/F and /sup 13/N-labeled radiotracers. This monograph treats the topic principally from the standpoint of synthetic organic chemistry while keeping in perspective the necessity of integrating the organic chemistry with the design and ultimate application of the radiotracer. Where possible, recent examples from the literature of organic synthesis are introduced to suggest potentially new routes which … more
Date: January 1, 1981
Creator: Fowler, J. S. & Wolf, A. P.
Partner: UNT Libraries Government Documents Department
open access

Photochemistry of psoralen-DNA adducts, biological effects of psoralen-DNA adducts, applications of psoralen-DNA photochemistry

Description: This thesis consists of three main parts and totally eight chapters. In Part I, The author will present studies on the photochemistry of psoralen-DNA adducts, specifically, the wavelength dependencies for the photoreversals of thymidine-HMT (4'-hydroxymethyl-4, 5', 8-trimenthylpsoralen) monoadducts and diadduct and the same adducts incorporated in DNA helices and the wavelength dependecies for the photocrossslinking of thymidine-HMT monoadducts in double-stranded helices. In Part II, The author… more
Date: March 1, 1988
Creator: Shi, Yun-bo
Partner: UNT Libraries Government Documents Department
open access

Mitotic Cycles in Meristems.

Description: No Description Available.
Date: January 1, 1969
Creator: Davidson, D.
Partner: UNT Libraries Government Documents Department
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