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open access

Influence of civil defense on strategic countervalue fatalities

Description: Two modeling studies were conducted to simulate the effect of fallout shelters on the outcome of a massive countervalue nuclear exchange between the Soviet Union and the United States. One was to determine the number of nuclear weapons required to mount an effective fallout attack against a country with dispersed population; the other was to determine the number of expected US fatalities resulting from a countervalue attack against US urban population centers. The results of these studies indic… more
Date: April 28, 1982
Creator: Harvey, T. F.
Partner: UNT Libraries Government Documents Department
open access

Afghanistan Casualties: Military Forces and Civilians

Description: Report collecting statistics from a variety of sources on casualties sustained during Operation Enduring Freedom (OEF), which began on October 7, 2001. OEF actions take place primarily in Afghanistan; however, OEF casualties also includes American casualties in Pakistan, Uzbekistan, Guantanamo Bay (Cuba), Djibouti, Eritrea, Ethiopia, Jordan, Kenya, Kyrgyzstan, the Philippines, Seychelles, Sudan, Tajikistan, Turkey, and Yemen.
Date: January 14, 2011
Creator: Chesser, Susan G.
Partner: UNT Libraries Government Documents Department
open access

Death and Ethnicity: A Psychocultural Study-Twenty-Five Years Later.

Description: his study compares ethnic, age, and gender differences concerning attitudes and behaviors toward death, dying, and bereavement among Caucasian, African, Hispanic, and Asian American adult participants in north Texas with the results of a 1976 study by Kalish and Reynolds on death attitudes and behaviors of Caucasian, African, Mexican, and Japanese American adult participants in Los Angeles, California. A modified version of Kalish and Reynolds' study questionnaire was administered to 526 respon… more
Date: December 2001
Creator: Peveto, Cynthia A.
Partner: UNT Libraries
open access

Dynamics of Adipocyte Turnover in Humans

Description: Obesity is increasing in an epidemic fashion in most countries and constitutes a public health problem by enhancing the risk for cardiovascular disease and metabolic disorders such as type 2 diabetes. Owing to the increase in obesity, life expectancy may start to decrease in developed countries for the first time in recent history. The factors determining fat mass in adult humans are not fully understood, but increased lipid storage in already developed fat cells is thought to be most important… more
Date: July 16, 2007
Creator: Spalding, K; Arner, E; Westermark, P; Bernard, S; Buchholz, B; Bergmann, O et al.
Partner: UNT Libraries Government Documents Department
open access

Safer Vehicles for People and the Planet: Letter to the Editor

Description: Letter to the Editors from Leonard Evans, Bloomfield Hills, MI: Single-vehicle crashes, which account for half of occupant fatalities, are not mentioned in 'Safer Vehicles for People and the Planet', by Thomas P. Wenzel and Marc Ross (March-April). Simple physics shows that in such crashes risk declines as vehicle mass increases. The authors write 'driving imported luxury cars carries extremely low risk, for reasons that are not obvious'. The reasons are obvious--the cars are purchased by low-r… more
Date: May 1, 2008
Creator: Wenzel, Thomas P; Wenzel, Thomas P & Ross, Marc
Partner: UNT Libraries Government Documents Department
open access

Telomere dysfunction and cell survival: roles for distinctTIN2-containing complexes

Description: Telomeres are maintained by three DNA binding proteins, TRF1, TRF2 and POT1, and several associated factors. One factor, TIN2, binds TRF1 and TRF2 directly and POT1 indirectly. These and two other proteins form a soluble complex that may be the core telomere-maintenance complex. It is not clear whether subcomplexes exist or function in vivo. Here, we provide evidence for two TIN2 subcomplexes with distinct functions in human cells. TIN2 ablation by RNA interference caused telomere uncapping and… more
Date: November 7, 2006
Creator: Kim, Sahn-Ho; Davalos, Albert R.; Heo, Seok-Jin; Rodier, Francis; Beausejour, Christian; Kaminker, Patrick et al.
Partner: UNT Libraries Government Documents Department
open access

Screening Program Reduced Melanoma Mortality at the Lawrence Livermore National Laboratory, 1984-1996

Description: Worldwide incidence of cutaneous malignant melanoma has increased substantially, and no screening program has yet demonstrated reduction in mortality. We evaluated the education, self examination and targeted screening campaign at the Lawrence Livermore National Laboratory (LLNL) from its beginning in July 1984 through 1996. The thickness and crude incidence of melanoma from the years before the campaign were compared to those obtained during the 13 years of screening. Melanoma mortality during… more
Date: October 12, 2006
Creator: Schneider, MD, J S; II, PhD, D & MD, PhD, M
Partner: UNT Libraries Government Documents Department
open access

Human cathepsin L rescues the neurodegeneration and lethality incathepsin B/L double deficient mice

Description: Cathepsin B (CTSB) and cathepsin L (CTSL) are two widelyexpressed cysteine proteases thought to predominantly reside withinlysosomes. Functional analysis of CTSL in humans is complicated by theexistence of two CTSL-like homologues (CTSL and CTSL2), in contrast tomice which contain only one CTSL enzyme. Thus transgenic expression ofhuman CTSL in CTSL deficient mice provides an opportunity to study the invivo functions of this human protease without interference by its highlyrelated homologue. Wh… more
Date: January 9, 2006
Creator: Sevenich, Lisa; Pennacchio, Len A.; Peters, Christoph & Reinheckel, Thomas
Partner: UNT Libraries Government Documents Department
open access

How Argonne's Intense Pulsed Neutron Source Came to Life and Gained Its Niche : The View From an Ecosystem Perspective.

Description: At first glance the story of the Intense Pulsed Neutron Source (IPNS) at Argonne National Laboratory (ANL) appears to have followed a puzzling course. When researchers first proposed their ideas for an accelerator-driven neutron source for exploring the structure of materials through neutron scattering, the project seemed so promising that both Argonne managers and officials at the laboratory's funding agency, the Department of Energy (DOE), suggested that it be made larger and more expensive. … more
Date: February 25, 2008
Creator: Westfall, C. & Director, Office of The
Partner: UNT Libraries Government Documents Department
open access

Role of a Transcriptional Regulator in Programmed Cell Death and Plant Development

Description: The long-term goal of this research is to understand the role(s) and molecular mechanisms of programmed cell death (PCD) in the controlling plant growth, development and responses to biotic and abiotic stress. We developed a genetic selection scheme to identify A. thaliana FB1-resistant (fbr) mutants as a way to find genes involved in PCD (Stone et al., 2000; Stone et al., 2005; Khan and Stone, 2008). The disrupted gene in fbr6 (AtSPL14) responsible for the FB1-insensitivity and plant architect… more
Date: September 13, 2008
Creator: Stone, Julie M.
Partner: UNT Libraries Government Documents Department
open access

Function-based Biosensor for Hazardous Waste Toxin Detection

Description: There is a need for new types of toxicity sensors in the DOE and other agencies that are based on biological function as the toxins encountered during decontamination or waste remediation may be previously unknown or their effects subtle. Many times the contents of the environmental waste, especially the minor components, have not been fully identified and characterized. New sensors of this type could target unknown toxins that cause death as well as intermediate levels of toxicity that impair … more
Date: July 9, 2008
Creator: Hickman, James J
Partner: UNT Libraries Government Documents Department
open access

Rap1 integrates tissue polarity, lumen formation, and tumorigenicpotential in human breast epithelial cells

Description: Maintenance of apico-basal polarity in normal breast epithelial acini requires a balance between cell proliferation, cell death, and proper cell-cell and cell-extracellular matrix signaling. Aberrations in any of these processes can disrupt tissue architecture and initiate tumor formation. Here we show that the small GTPase Rap1 is a crucial element in organizing acinar structure and inducing lumen formation. Rap1 activity in malignant HMT-3522 T4-2 cells is appreciably higher than in S1 cells,… more
Date: September 29, 2006
Creator: Itoh, Masahiko; Nelson, Celeste M.; Myers, Connie A. & Bissell,Mina J.
Partner: UNT Libraries Government Documents Department
open access

Change in cell shape is required for matrix metalloproteinase-induced epithelial-mesenchymal transition of mammary epithelial cells

Description: Cell morphology dictates response to a wide variety of stimuli, controlling cell metabolism, differentiation, proliferation, and death. Epithelial-mesenchymal transition (EMT) is a developmental process in which epithelial cells acquire migratory characteristics, and in the process convert from a 'cuboidal' epithelial structure into an elongated mesenchymal shape. We had shown previously that matrix metalloproteinase-3 (MMP3) can stimulate EMT of cultured mouse mammary epithelial cells through … more
Date: June 26, 2008
Creator: Nelson, Celeste M.; Khauv, Davitte; Bissell, Mina J. & Radisky, Derek C.
Partner: UNT Libraries Government Documents Department
open access

How safe are nuclear plants. How safe should they be

Description: It has become customary to think about safety of nuclear plants in terms of risk as defined by the WASH-1400 study that some of the implications for the non-specialist escape our attention. Yet it is known that a rational program to understand safety, to identify unsafe events, and to use this kind of information or analysis to improve safety, requires us to use the methods of quantitative risk assessment. How this process can be made more understandable to a broader group of nontechnical peopl… more
Date: January 1, 1988
Creator: Kouts, H.
Partner: UNT Libraries Government Documents Department
open access

Assessment of the risk of transporting gasoline by truck

Description: Based on shipping assumptions and the current accident rate of 2.5 x 10/sup -6/ per mile, it is estimated that gasoline tank trucks will be involved in 1,781 accidents in 1980, and that 110 of the accidents (about one in 15) will result in a release of 3,000 gallons of gasoline or more from the tank truck. About one in four of the releases are expected to result in a large fire. The estimated number of fatalities from the gasoline releases in 1980 is 29, with 12 of these fatalities being driver… more
Date: November 1, 1978
Partner: UNT Libraries Government Documents Department
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A Mathematical Model for Predicting the Probability of Acute Mortality in a Human Population Exposed to Accidentally Released Airborne Radionuclides. Final Report for Phase I of the Project: Early Effects of Inhaled Radionuclides

Description: The report presents a mathematical model for the purpose of predicting the fraction of human population which would die within 1 year of an accidental exposure to airborne radionuclides. The model is based on data from laboratory experiments with rats, dogs and baboons, and from human epidemiological data. Doses from external, whole-body irradiation and from inhaled, alpha- and beta-emitting radionuclides are calculated for several organs. The probabilities of death from radiation pneumonitis a… more
Date: June 1, 1980
Creator: Filipy, R. E.; Borst, F. J.; Cross, F. T.; Park, J. F.; Moss, O. R.; Roswell, R. L. et al.
Partner: UNT Libraries Government Documents Department
open access

Models for comparing lung-cancer risks in radon- and plutonium-exposed experimental animals

Description: Epidemiologic studies of radon-exposed underground miners have provided the primary basis for estimating human lung-cancer risks resulting from radon exposure. These studies are sometimes used to estimate lung-cancer risks resulting from exposure to other alpha- emitters as well. The latter use, often referred to as the dosimetric approach, is based on the assumption that a specified dose to the lung produces the same lung-tumor risk regardless of the substance producing the dose. At Pacific No… more
Date: October 1, 1990
Creator: Gilbert, E. S.; Cross, F. T.; Sanders, C. L. & Dagle, G. E.
Partner: UNT Libraries Government Documents Department
open access

Pilot study risk assessment for selected problems at the Savannah River Site (SRS)

Description: An assessment of the health risks was made for releases of tritium and [sup 137]Cs from the Savannah River Site (SRS) at water-receptor locations downriver. Although reactor operations were shut down at the SRS in 1989, liquid wastes continue to be released to the Savannah River either by direct discharges into onsite surface waters or by groundwater transport into surface waters from waste facilities. Existing state mandates will cause the liquid waste streams from future operations to go dire… more
Date: March 1, 1993
Creator: Hamilton, L.D.; Holtzman, S.; Meinhold, A.; Morris, S.C.; Pardi, R.; Sun, C. (Brookhaven National Lab., Upton, NY (United States)) et al.
Partner: UNT Libraries Government Documents Department
open access

Afghanistan Casualties: Military Forces and Civilians

Description: This report presents statistics from a variety of sources on casualties sustained during Operation Enduring Freedom (OEF), which began on October 7, 2001, and is ongoing. OEF actions take place primarily in Afghanistan; however, OEF casualties also includes American casualties in Pakistan, Uzbekistan, Guantanamo Bay (Cuba), Djibouti, Eritrea, Ethiopia, Jordan, Kenya, Kyrgyzstan, the Philippines, Seychelles, Sudan, Tajikistan, Turkey, and Yemen.
Date: August 3, 2011
Creator: Chesser, Susan G.
Partner: UNT Libraries Government Documents Department
open access

Japan’s 2011 Earthquake and Tsunami: Economic Effects and Implications for the United States

Description: This report presents data regarding the persons killed, missing, and buildings totally or partially damaged after the disaster in Japan. The report discusses the economic impact the disaster had on Japan and the impact on U.S. imports from and exports to Japan.
Date: March 25, 2011
Creator: Nanto, Dick K.; Cooper, William H. & Donnelly, J. Michael
Partner: UNT Libraries Government Documents Department
open access

Studies of acute and chronic radiation injury at the Biological and Medical Research Division, Argonne National Laboratory, 1970-1992: The JANUS Program Survival and Pathology Data

Description: A research reactor for exclusive use in experimental radiobiology was designed and built at Argonne National Laboratory in the 1960`s. It was located in a special addition to Building 202, which housed the Division of Biological and Medical Research. Its location assured easy access for all users to the animal facilities, and it was also near the existing gamma-irradiation facilities. The water-cooled, heterogeneous 200-kW(th) reactor, named JANUS, became the focal point for a range of radiobio… more
Date: February 1995
Creator: Grahn, D.; Wright, B. J.; Carnes, B. A.; Williamson, F. S. & Fox, C.
Partner: UNT Libraries Government Documents Department
open access

Data available from birth and death registries and cancer registries in the United States

Description: In the United States, cancer registries have been compiling data for decades, and state vital statistics offices have been compiling birth and death data for nearly a century. Although this information has been well used for disease surveillance and various studies, it could be better exploited by making it more readily available, reducing the duplication of effort that occurs when researchers at the private, city, county, state, and federal levels work separately on their data collection and d… more
Date: January 1, 1994
Creator: Wallin, B. L.; Houser, A. R.; Merrill, D. W. & Selvin, S.
Partner: UNT Libraries Government Documents Department
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