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Computational Biology, Advanced Scientific Computing, and Emerging Computational Architectures

Description: This CRADA was established at the start of FY02 with $200 K from IBM and matching funds from DOE to support post-doctoral fellows in collaborative research between International Business Machines and Oak Ridge National Laboratory to explore effective use of emerging petascale computational architectures for the solution of computational biology problems. 'No cost' extensions of the CRADA were negotiated with IBM for FY03 and FY04.
Date: June 27, 2007
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

Argonne National Laboratory Summary Site Environmental Report for Calendar Year 2006.

Description: This booklet is designed to inform the public about what Argonne National Laboratory is doing to monitor its environment and to protect its employees and neighbors from any adverse environmental impacts from Argonne research. The Downers Grove South Biology II class was selected to write this booklet, which summarizes Argonne's environmental monitoring programs for 2006. Writing this booklet also satisfies the Illinois State Education Standard, which requires that students need to know and appl… more
Date: March 27, 2008
Creator: Golchert, N. W. & Oversight, ESH /QA
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

Remaining Sites Verification Package for the 100-F-52, 146-FR Radioecology and Aquatic Biology Laboratory Soil, Waste Site Reclassification Form 2008-022

Description: The 100-F-52 waste site consisted of the soil under and around the former 146-FR Radioecology and Aquatic Biology Laboratory. The laboratory was used for studies of the effects of pre-reactor and post-reactor process water on fish eggs, young fish, and other small river creatures of interest. In accordance with this evaluation, the confirmatory sampling results support a reclassification of this site to No Action. The current site conditions achieve the remedial action objectives and the corres… more
Date: June 27, 2008
Creator: Capron, J. M.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

Using Femtosecond Laser Subcellular Surgery as a Tool to Study Cell Biology

Description: Research on cellular function and regulation would be greatly advanced by new instrumentation using methods to alter cellular processes with spatial discrimination on the nanometer-scale. We present a novel technique for targeting submicrometer sized organelles or other biologically important regions in living cells using femtosecond laser pulses. By tightly focusing these pulses beneath the cell membrane, we can vaporize cellular material inside the cell through nonlinear optical processes. Th… more
Date: February 27, 2007
Creator: Shen, N; Colvin, M E & Huser, T
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

Global Regulatory Pathways in the Alphaproteobacteria

Description: A major goal for microbiologists in the twenty-first century is to develop an understanding of the microbial cell in all its complexity. In addition to understanding the function of individual gene products we need to focus on how the cell regulates gene expression at a global level to respond to different environmental parameters. Development of genomic technologies such as complete genome sequencing, proteomics, and global comparisons of mRNA expression patterns allows us to begin to address … more
Date: April 27, 2007
Item Type: Refine your search to only Text
Partner: UNT Libraries Government Documents Department
open access

Ultra-fast Coherent Diffraction Imaging of Single Particles, Clusters and Biomolecules

Description: Theoretical studies and simulations predict that with a very short and very intense coherent X-ray pulse a single diffraction pattern may be recorded from a large macromolecule, a virus, or a cell without the need for crystalline periodicity. Measurement of the over-sampled X-ray diffraction pattern permits phase retrieval and hence structure determination. Although individual samples will be destroyed by the very intense X-ray pulse, a three-dimensional data set could be assembled when copies … more
Date: September 27, 2006
Creator: Hajdu, J & Chapman, H
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

Global Biogeochemistry Models and Global Carbon Cycle Research at Lawrence Livermore National Laboratory

Description: The climate modeling community has long envisioned an evolution from physical climate models to ''earth system'' models that include the effects of biology and chemistry, particularly those processes related to the global carbon cycle. The widely reproduced Box 3, Figure 1 from the 2001 IPCC Scientific Assessment schematically describes that evolution. The community generally accepts the premise that understanding and predicting global and regional climate change requires the inclusion of carbo… more
Date: May 27, 2005
Creator: Covey, C; Caldeira, K; Guilderson, T; Cameron-Smith, P; Govindasamy, B; Swanston, C et al.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

Characterization of Pathogenicity, Virulence and Host-Pathogen Interractions

Description: The threats of bio-terrorism and newly emerging infectious diseases pose serious challenges to the national security infrastructure. Rapid detection and diagnosis of infectious disease in human populations, as well as characterizing pathogen biology, are critical for reducing the morbidity and mortality associated with such threats. One of the key challenges in managing an infectious disease outbreak, whether through natural causes or acts of overt terrorism, is detection early enough to initia… more
Date: July 27, 2006
Creator: Krishnan, A. & Folta, P.
Item Type: Refine your search to only Article
Partner: UNT Libraries Government Documents Department
open access

Update on the Pfam5000 Strategy for Selection of Structural Genomics Targets

Description: Structural Genomics is an international effort to determine the three-dimensional shapes of all important biological macromolecules, with a primary focus on proteins. Target proteins should be selected according to a strategy that is medically and biologically relevant, of good financial value, and tractable. In 2003, we presented the ''Pfam5000'' strategy, which involves selecting the 5,000 most important families from the Pfam database as sources for targets. In this update, we show that alth… more
Date: June 27, 2005
Creator: Chandonia, John-Marc & Brenner, Steven E.
Item Type: Refine your search to only Article
Partner: UNT Libraries Government Documents Department
open access

EM Structure Based and Vacuum Acceleration

Description: The importance of particle acceleration may be judged from the number of applications which require some sort of accelerated beam. In addition to accelerator-based high energy physics research, non-academic applications include medical imaging and treatment, structural biology by x-ray diffraction, pulse radiography, cargo inspection, material processing, food and medical instrument sterilization, and so on. Many of these applications are already well served by existing technologies and will pr… more
Date: September 27, 2005
Creator: Colby, E. R.
Item Type: Refine your search to only Article
Partner: UNT Libraries Government Documents Department
open access

Damage-resistant single-pulse optics for x-ray free electron lasers

Description: Short-pulse ultraviolet and x-ray free electron lasers of unprecedented peak brightness are in the process of revolutionizing physics, chemistry, and biology. Optical components for these new light sources have to be able to withstand exposure to the extremely high-fluence photon pulses. Whereas most optics have been designed to stay intact for many pulses, it has also been suggested that single-pulse optics that function during the pulse but disintegrate on a longer timescale, may be useful at… more
Date: April 27, 2007
Creator: Hau-Riege, S.; London, R.; Bogan, M.; Chapman, H. & Bergh, M.
Item Type: Refine your search to only Article
Partner: UNT Libraries Government Documents Department
open access

Geographical and Temporal Dynamics of Chaetocnema Pulicaria and Their Role in Stewart's Disease of Corn in Iowa

Description: This thesis investigated the biology and importance of the corn flea beetle vector and its role in the Stewart's disease of corn pathosystem. This was accomplished by determining the number of corn flea beetle generations that occur in Iowa and by quantifying the proportions of those populations found to be infested with the causal agent of Stewart's disease, pantoea stewartii. In addition, a preliminary study was conducted to determine how soil temperature was influenced by air temperature and… more
Date: May 27, 2001
Creator: Esker, Paul David
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries Government Documents Department
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