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open access

Heterogeneous processes at the intersection of chemistry and biology: A computational approach

Description: Heterogeneous processes hold the key to understanding many problems in biology and atmospheric science. In particular, recent experiments have shown that heterogeneous chemistry at the surface of sea-salt aerosols plays a large role in important atmospheric processes with far reaching implications towards understanding of the fate and transport of aerosolized chemical weapons (i.e. organophosphates such as sarin and VX). Unfortunately, the precise mechanistic details of the simplest surface enh… more
Date: February 11, 2008
Creator: Kuo, I W & Mundy, C J
Partner: UNT Libraries Government Documents Department
open access

Mutations that Cause Human Disease: A Computational/Experimental Approach

Description: International genome sequencing projects have produced billions of nucleotides (letters) of DNA sequence data, including the complete genome sequences of 74 organisms. These genome sequences have created many new scientific opportunities, including the ability to identify sequence variations among individuals within a species. These genetic differences, which are known as single nucleotide polymorphisms (SNPs), are particularly important in understanding the genetic basis for disease susceptibi… more
Date: January 11, 2006
Creator: Beernink, P; Barsky, D & Pesavento, B
Partner: UNT Libraries Government Documents Department
open access

TECHNICAL REPORT

Description: Because this DOE grant was abruptly terminated without warning, this group was not able to accomplish the insertion of the biosensor genes into the mouse lines. They have been able to generate some of the mouse lines but have not been able to complete the ones that would give them the model systems that would allow them to investigate metastasis real-time in living tumors at the cellular level. Nonetheless, until the loss of funding, they have made progress in applications of the equipment to b… more
Date: October 11, 2007
Creator: SINGER, DR. ROBERT
Partner: UNT Libraries Government Documents Department
open access

Wavelet based characterization of ex vivo vertebral trabecular bone structure with 3T MRI compared to microCT

Description: Trabecular bone structure and bone density contribute to the strength of bone and are important in the study of osteoporosis. Wavelets are a powerful tool to characterize and quantify texture in an image. In this study the thickness of trabecular bone was analyzed in 8 cylindrical cores of the vertebral spine. Images were obtained from 3 Tesla (T) magnetic resonance imaging (MRI) and micro-computed tomography ({micro}CT). Results from the wavelet based analysis of trabecular bone were compared … more
Date: April 11, 2005
Creator: Krug, R.; Carballido-Gamio, J.; Burghardt, A.; Haase, S.; Sedat, J. W.; Moss, W. C. et al.
Partner: UNT Libraries Government Documents Department
open access

Discussion: Reporting and calibration of post-bomb 14C data

Description: The definitive paper by Stuiver and Polach (1977) established the conventions for reporting of {sup 14}C data for chronological and geophysical studies based on the radioactive decay of {sup 14}C in the sample since the year of sample death or formation. Several ways of reporting {sup 14}C activity levels relative to a standard were also established, but no specific instructions were given for reporting nuclear weapons testing (post-bomb) {sup 14}C levels in samples. Because the use of post-bom… more
Date: October 11, 2004
Creator: Reimer, P J; Brown, T A & Reimer, R W
Partner: UNT Libraries Government Documents Department
open access

2001 DC Lecture Series: The New Biology - Challenges and Opportunities

Description: The Whitehead Institute for Biomedical Research, in collaboration with Center for Strategic and International Studies (CSIS), developed a series of seminars, ''The New Biology: Challenges and Opportunities'', to stimulate dialogue between leaders in science, medicine, law, biotechnology and senior government policymakers on matters that will shape much of the genomic revolution's impact on individuals and institutions in this country.
Date: April 11, 2006
Partner: UNT Libraries Government Documents Department
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