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Tissue biodistribution of intravenously administrated titanium dioxide nanoparticles revealed blood-brain barrier clearance and brain inflammation in rat

Description: This article reports time-related responses from single-dose intravenous administration of 1 mg/kg Ti₂ NPs to rats, with particular emphasis on titanium quantification in the brain.
Date: September 4, 2015
Creator: Disdier, Clémence; Devoy, Jérôme; Cosnefroy, Anne; Chalansonnet, Monique; Herlin-Boime, Nathalie; Brun, Emilie et al.
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Partner: UNT College of Arts and Sciences
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Methods and results from the genome-wide association group at GAW20

Description: This article reports on promising statistical approaches and findings of the members of the Genome-wide Association Study group applied on real and simulated data which encompass the current topics of epigenetic and pharmacogenomics.
Date: September 17, 2018
Creator: Wang, Xuexia; Boekstegers, Felix & Brinster, Regina
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Partner: UNT College of Arts and Sciences
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Parallel expression evolution of oxidative stress-related genes in fiber from wild and domesticated diploid and polyploid cotton (Gossypium)

Description: This article studies the evolution of oxidative stress related genes in a single plant cell by conducting comparative expression profiling analyses of the elongated seed trichomes of cotton, using a phylogenetic approach.
Date: August 17, 2009
Creator: Chaudhary, Bhupendra; Hovav, Ran; Flagel, Lex; Mittler, Ron & Wendel, Jonathan F.
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Partner: UNT College of Arts and Sciences
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Elucidating the multifunctional role of the cell wall components in the maize exploitation

Description: Article on the composition of the four cell wall fractions in diverse maize genotypes and to understand how this composition influences the resistance to pests, ethanol capacity and digestibility. Results evidence that there is no maize cell wall ideotype among the tested for optimal performance for various uses, and maize plants should be specifically bred for each particular application.
Date: June 2, 2021
Creator: López-Malvar, Ana; Malvar, Rosa Ana; Souto, Xose Carlos; Gomez, Leonardo Dario; Simister, Rachael; Encina, Antonio et al.
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Partner: UNT College of Science
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Genome-wide analysis of the omega-3 fatty acid desaturase gene family in Gossypium

Description: This article identifies and characterizes the omega-3 fatty acid desaturase gene family in Gossypium hirsutum, with an emphasis on identifying omega-3 fatty acid desaturase involved in cold temperature adaption.
Date: November 18, 2014
Creator: Yurchenko, Olga P.; Park, Sunjung; Ilut, Daniel C.; Inmon, Jay J.; Millhollon, Jon C.; Liechty, Zach et al.
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Partner: UNT College of Arts and Sciences
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A cytochrome P450 monooxygenase commonly used for negative selection in transgenic plants causes growth anomalies by disrupting brassinosteroid signaling

Description: Article on a cytochrome P450 monooxygenase commonly used for negative selection in transgenic plants causing growth anomalies by disrupting brassinosteroid signaling.
Date: April 15, 2011
Creator: Dasgupta, Kasturi; Ganesan, Savita; Manivasagam, Sindhu & Ayre, Brian G.
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Partner: UNT College of Arts and Sciences
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HSI2/VAL1 PHD-like domain promotes H3K27 trimethylation to repress the expression of seed maturation genes and complex transgenes in Arabidopsis seedlings

Description: This article studies the novel mutant allele hsi2-4, isolated in a genetic screen to identify Arabidopsis mutants with consitutively elevated expression of a glutathione S-transferase F8:luciferase reporter gene in Arabidopsis.
Date: November 1, 2014
Creator: Veerappan, Vijaykumar; Chen, Naichong; Reichert, Angelika & Allen, Randy D.
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Partner: UNT College of Arts and Sciences
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Development and use of a switchgrass (Panicum virgatum L.) transformation pipeline by the BioEnergy Science Center to evaluate plants for reduced cell wall recalcitrance

Description: Article examines the creation of a transformation pipeline (TP) to produce plants with decreased recalcitrance and a laboratory information management system (LIMS) for data compilation from these plants. While many genes accepted into the TP resulted in transgenic switchgrass without modified lignin or biomass content, a group of genes with potential to improve lignocellulosic biofuel yields was identified. Results from transgenic lines targeting xyloglucan and lignin structure provide example… more
Date: December 22, 2017
Creator: Nelson, Richard S.; Stewart, C. Neal; Gou, Jiqing; Holladay, Susan; Gallego-Giraldo, Lina; Flanagan, Amy et al.
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Partner: UNT College of Science
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Combining loss of function of FOLYLPOLYGLUTAMATE SYNTHETASE1 and CAFFEOYL-COA 3-O-METHYLTRANSFERASE1 for lignin reduction and improved saccharification efficiency in Arabidopsis thaliana

Description: This article tests if lignin content can be further reduced by combining genetic mutations in C1 metabolism and the lignin biosynthetic pathway by generating and functionally characterizing fpgs1ccoaomt1 double mutants. The observations demonstrate that additional reduction in lignin content and improved sugar release can be achieved by simultaneous downregulation of a gene in the C1 (FPGS1) and lignin biosynthetic (CCOAOMT) pathways.
Date: May 3, 2019
Creator: Xie, Hongli; Engle, Nancy L.; Venketachalam, Sivasankari; Yoo, Chang Geun; Barros, Jaime; Lecoultre, Mitch et al.
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Partner: UNT College of Science
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Multiple levers for overcoming the recalcitrance of lignocellulosic biomass

Description: The article evaluates the impacts of physical, chemical and genetic interventions to improve biomass processing singly and in combination. Based on their results and literature studies, some form of non-biological augmentation will likely be necessary for the foreseeable future to achieve high total carbohydrate solubilization (TCS) for most cellulosic feedstocks. The results show that this need not necessarily involve thermochemical processing, and need not necessarily occur prior to biologica… more
Date: January 17, 2019
Creator: Holwerda, Evert; Worthen, Robert; Kothari, Ninad; Lasky, Ronald; Davison, Brian H. (Brian Henry), 1957-; Fu, Chunxiang et al.
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Partner: UNT College of Science
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Targeting hydroxycinnamoyl CoA: shikimate hydroxycinnamoyl transferase for lignin modification in Brachypodium distachyon

Description: This article conducts a study to evaluate the utility of Hydroxycinnamoyl CoA: shikimate hydroxycinnamoyl transferase (HCT) as a target for lignin modification in a species with an “incomplete” shikimate shunt. Results imply that this gene is a preferred target for biotechnological improvement of grasses for bioprocessing.
Date: February 27, 2021
Creator: Serrani-Yarce, Juan Carlos; Escamilla-Treviño, Luis; Barros, Jaime; Gallego-Giraldo, Lina; Pu, Yunqiao; Ragauskas, Arthur J. (Arthur Jonas), 1957- et al.
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Partner: UNT College of Science
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A rapid thioacidolysis method for biomass lignin composition and tricin analysis

Description: This article developed a modified, rapid higher throughput thioacidolysis method to analyze both lignin monomeric composition and tricin content in the lignin polymer. The results demonstrate that the modified method can be used for rapid, high-throughput, and reliable lignin composition and tricin content analyses for screening transgenic plants for cell wall modifications or in large-scale genome-wide association studies (GWAS).
Date: January 11, 2021
Creator: Chen, Fang; Zhuo, Chunliu; Xiao, Xirong; Pendergast, Thomas H. & Devos, Katrien M.
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Partner: UNT College of Science
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A deep transcriptomic analysis of pod development in the vanilla orchid (Vanilla planifolia)

Description: This research article describes very large gene sequence datasets from vanilla pods at different times of development, representing different tissue types, including the seeds, hairs, and placental and mesocarp tissues within the pod.
Date: November 7, 2014
Creator: Rao, Xiaolan; Krom, Nick; Tang, Yuhong; Widiez, Thomas; Havkin-Frenkel, Daphna; Belanger, Faith C. et al.
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Partner: UNT College of Arts and Sciences
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Whole genome comparisons of Fragaria, Prunus and Malus reveal different modes of evolution between Rosaceous subfamilies

Description: Article discussing whole genome comparisons of Fragaria, Prunus and Malus revealing different modes of evolution between Rosaceous subfamilies.
Date: April 4, 2012
Creator: Jung, Sook; Cestaro, Alessandro; Troggio, Michela; Main, Dorrie; Zheng, Ping; Cho, Ilhyung et al.
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Partner: UNT College of Arts and Sciences
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Rapid identification of causative insertions underlying Medicago truncatula Tnt1 mutants defective in symbiotic nitrogen fixation from a forward genetic screen by whole genome sequencing

Description: This article demonstrates that whole genome sequencing is an efficient approach for identification of causative genes underlying symbiotic nitrogen fixation defective phenotypes in Medicago truncatula Tnt1 insertion mutants obtained via forward genetic screens.
Date: February 27, 2016
Creator: Veerappan, Vijaykumar; Jani, Mehul; Kadel, Khem; Troiani, Taylor; Gale, Ronny; Mayes, Tyler et al.
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Partner: UNT College of Arts and Sciences
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