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open access

Elemental Concentrations in the Seed of Mutants and Natural Variants of Arabidopsis thaliana Grown under Varying Soil Conditions

Description: Article on elemental concentrations in the seed of mutants and natural variants of Arabidopsis thaliana grown under varying soil conditions.
Date: May 2013
Creator: McDowell, Stephen C.; Akmakjian, Garo; Sladek, Chris; Mendoza-Cózatl, David; Morrissey, Joe B.; Saini, Nick et al.
Partner: UNT College of Arts and Sciences
open access

Nutrient-Deprivation Autophagy Factor-1 (NAF-1): Biochemical Properties of a Novel Cellular Target for Anti-Diabetic Drugs

Description: Article on nutrient-deprivation autophagy factor-1 (NAF-1) and biochemical properties of a novel cellular target for anti-diabetic drugs.
Date: May 22, 2013
Creator: Tamir, Sagi; Zuris, John A.; Agranat, Lily; Lipper, Colin H.; Conlan, Andrea R.; Michaeli, Dorit et al.
Partner: UNT College of Arts and Sciences
open access

Nutrient-Deprivation Autophagy Factor-1 (NAF-1): Biochemical Properties of a Novel Cellular Target for Anti-Diabetic Drugs

Description: Article on nutrient-deprivation autophagy factor-1 (NAF-1) and biochemical properties of a novel cellular target for anti-diabetic drugs.
Date: May 22, 2013
Creator: Tamir, Sagi; Zuris, John A.; Agranat, Lily; Lipper, Colin H.; Conlan, Andrea R.; Michaeli, Dorit et al.
Partner: UNT College of Arts and Sciences
open access

Ultra-Fast Alterations in mRNA Levels Uncover Multiple Players in Light Stress Acclimation in Plants

Description: This article contains RNA sequencing analysis of Arabidopsis thaliana plants subjected to light stress in order to identify and characterize rapid changes in the steady-state level of different transcripts in response to light stress.
Date: September 26, 2015
Creator: Suzuki, Nobuhiro; Devireddy, Amith R.; Inupakutika, Madhuri A.; Baxter, Aaron; Miller, Gad; Song, Luhua et al.
Partner: UNT College of Arts and Sciences
open access

Phylogenetic analysis of eukaryotic NEET proteins uncovers a link between a key gene duplication event and the evolution of vertebrates

Description: This article describes the use of three members of the human NEET protein family (CISD1, mitoNEET; CISD2, NAF-1 or Miner 1; and CISD3, Miner2) as guides to conduct a phylogenetic analysis of eukaryotic NEET proteins and their evolution.
Date: February 16, 2017
Creator: Inupakutika, Madhuri A.; Sengupta, Soham; Nechushtai, Rachel; Jennings, Patricia A.; Onuchic, José N.; Azad, Rajeev K. et al.
Partner: UNT College of Arts and Sciences
open access

Cancer-Related NEET Proteins Transfer 2Fe-2S Clusters to Anamorsin, a Protein Required for Cytosolic Iron-Sulfur Cluster Biogenesis

Description: This article reports the first physiological 2Fe-2S cluster acceptor for both NEET proteins as human Anamorsin (also known as cytokine induced apoptosis inhibitor-1; CIAPIN-1).
Date: October 8, 2015
Creator: Lipper, Colin H.; Paddock, Mark L.; Onuchic, José N.; Mittler, Ron; Nechushtai, Rachel & Jennings, Patricia A.
Partner: UNT College of Arts and Sciences
open access

Manipulating Sucrose Proton Symporters to Understand Phloem Loading

Description: Phloem vascular tissues transport sugars synthesized by photosynthesis in mature leaves by a process called phloem loading in source tissues and unloading in sink tissues. Phloem loading in source leaves is catalyzed by Suc/H+ symporters (SUTs) which are energized by proton motive force. In Arabidopsis the principal and perhaps exclusive SUT catalyzing phloem loading is AtSUC2. In mutant plants harboring a T-DNA insertion in each of the functional SUT-family members, only Atsuc2 mutants demonst… more
Date: August 2013
Creator: Dasgupta, Kasturi
Partner: UNT Libraries
open access

ABA is required for the accumulation of APX1 and MBF1c during a combination of water deficit and heat stress

Description: This article studies the response of mutants impaired in ABA signalling (abi1-1) and biosynthesis (aba1-1) to a combination of water deficit and heat stress.
Date: July 18, 2016
Creator: Zandalinas, Sara I.; Balfagón, Damián; Arbona, Vicent; Gómez-Cadenas, Aurelio; Inupakutika, Madhuri A. & Mittler, Ron
Partner: UNT College of Arts and Sciences
open access

Enhanced seed production under prolonged heat stress conditions in Arabidopsis thaliana plants deficient in cytosolic ascorbate peroxidase 2

Description: Article discussing enhanced seed production under prolonged heat stress conditions in Arabidopsis thaliana plants deficient in cytosolic ascorbate peroxidase 2.
Date: November 26, 2012
Creator: Suzuki, Nobuhiro; Miller, Gad; Sejima, Hiroe; Harper, Jeffrey F. & Mittler, Ron
Partner: UNT College of Arts and Sciences
open access

The Water-Water Cycle Is Essential for Chloroplast Protection in the Absence of Stress

Description: Article showing that knockdown Arabidopsis plants with suppressed expression of the key water-water cycle enzyme, thylakoid-attached copper/zinc superoxide dismutase (KD-SOD), are suppressed in their growth and development. This article provides e genetic evidence for the importance of the water-water cycle in protecting the photosynthetic apparatus of higher plants from photooxidative damage.
Date: October 3, 2003
Creator: Rizhsky, Ludmila; Liang, Hongjian & Mittler, Ron
Partner: UNT College of Science
open access

The Transcriptional Co-activator MBF1c Is a Key Regulator of Thermotolerance in Arabidopsis thaliana

Description: Article reporting that the highly conserved transcriptional co-activator, MBF1c (multiprotein bridging factor 1c), is a key regulator of thermotolerance in Arabidopsis thaliana. Results provide evidence for the existence of a tightly coordinated heat stress-response network, involving trehalose-, SA-, and ethylene-signaling pathways, that is under the control of MBF1c.
Date: April 4, 2008
Creator: Suzuki, Nobuhiro; Bajad, Sunil; Shuman, Joel; Shulaev, Vladimir & Mittler, Ron
Partner: UNT College of Science
open access

Ascorbate Peroxidase 1 Plays a Key Role in the Response of Arabidopsis thaliana to Stress Combination

Description: Article conducting proteomic and metabolic analysis of Arabidopsis thaliana plants subjected to a combination of drought and heat stress. The authors identify 45 different proteins that specifically accumulated in Arabidopsis in response to the stress combination. The findings suggest that cytosolic APX1 plays a key role in the acclimation of plants to a combination of drought and heat stress.
Date: December 5, 2008
Creator: Koussevitzky, Shai; Suzuki, Nobuhiro; Huntington, Serena; Armijo, Leigh; Sha, Wei; Cortes, Diego F. et al.
Partner: UNT College of Science
open access

The EAR-motif of the Cys2/His2-type Zinc Finger Protein Zat7 Plays a Key Role in the Defense Response of Arabidopsis to Salinity Stress

Description: Article reporting that transgenic Arabidopsis plants constitutively expressing the Cys2/His2 zinc finger protein Zat7 have suppressed growth and are more tolerant to salinity stress. Findings demonstrate that the EAR-domain of Cys2/His2-type zinc finger proteins plays a key role in the defense response of Arabidopsis to abiotic stresses.
Date: March 23, 2007
Creator: Ciftci-Yilmaz, Sultan; Morsy, Mustafa R.; Song, Luhua; Coutu, Alicia; Krizek, Beth A.; Lewis, Michael W. et al.
Partner: UNT College of Science
open access

Unraveling Δ1-Pyrroline-5-Carboxylate-Proline Cycle in Plants by Uncoupled Expression of Proline Oxidation Enzymes

Description: Article showing that overexpression of MsProDH in tobacco and Arabidopsis or impairment of P5C oxidation in the Arabidopsis p5cdh mutant did not change the cellular Pro to P5C ratio under ambient and osmotic stress conditions, indicating that P5C excess was reduced to Pro in a mitochondrial-cytosolic cycle. Results show that normal oxidation of P5C to Glu by P5CDH is key to prevent P5C-Pro intensive cycling and avoid ROS production from electron run-off.
Date: September 25, 2009
Creator: Miller, Gad; Honig, Arik; Stein, Hanan; Suzuki, Nobuhiro; Mittler, Ron & Zilberstein, Aviah
Partner: UNT College of Science
open access

Evidence for the Involvement of Electrical, Calcium and ROS Signaling in the Systemic Regulation of Non-Photochemical Quenching and Photosynthesis

Description: Article presents study in which pulse amplitude-modulated Chl fluorescence imaging and surface electrical potential measurements accompanied by pharmacological treatments were employed to study stimuli-induced electrical signals in leaves from a broad range of plant species and in Arabidopsis thaliana mutants.
Date: February 10, 2017
Creator: Białasek, Maciej; Górecka, Magdalena; Mittler, Ron & Karpiński, Stanisław
Partner: UNT College of Arts and Sciences
open access

Rapid Responses to Abiotic Stress: Priming the Landscape for the Signal Transduction Network

Description: This article proposes that a plant's ability to engage in many different metabolic and molecular networks as well as alter stomatal aperture in order to adapt to their environment is mediated through pulses of gene expression that are coordinated throughout the plant in a systemic manner by the ROS/Ca+2 waves.
Date: January 2019
Creator: Kollist, Hannes; Zandalinas, Sara I.; Sengupta, Soham; Nuhkat, Maris; Kangasjärvi, Jaakko & Mittler, Ron
Partner: UNT College of Liberal Arts & Social Sciences
open access

Detection and Classification of Cancer and Other Noncommunicable Diseases Using Neural Network Models

Description: Here, we show that training with multiple noncommunicable diseases (NCDs) is both feasible and beneficial to modeling this class of diseases. We first use data from the Cancer Genome Atlas (TCGA) to train a pan cancer model, and then characterize the information the model has learned about the cancers. In doing this we show that the model has learned concepts that are relevant to the task of cancer classification. We also test the model on datasets derived independently of the TCGA cohort and s… more
Date: July 2023
Creator: Gore, Steven Lee
Partner: UNT Libraries
open access

Identification and characterization of a core set of ROS wave‐associated transcripts involved in the systemic acquired acclimation response of Arabidopsis to excess light

Description: Article reveal that the systemic transcriptomic response of plants to excess light stress is extensive in the context of systemic acquired acclimation and involves an early (2 min) and transient stage of transcript expression that includes thousands of genes.
Date: December 6, 2018
Creator: Zandalinas, Sara I.; Sengupta, Soham; Burks, David; Azad, Rajeev K. & Mittler, Ron
Partner: UNT College of Science
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