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- Evolução do Sarcoma 37 em Muganhos CF1. Aspectos biológicos da cura espontiânea do tumor estudados após Irradiação e administração de soro "imune"
- Transplants of sarcoma 37 were studied in regard to spontaneous regression of the tumor after irradiation and after the administration of immune serum. The following results were obtained: 1. Of 809 animals, 99% developed the tumor after transplantation; 2. The number of cells transplanted did not influence the growth rate, the percentage of spontaneous regressions, or the life spans of the animals; 3. Reimplantation of the tumor into mice which had previously rejected the tumor resulted in very few successful transplants; 4. The resistance of these mice to further attempts at implantation could not be altered by previous irradiation; 5. Animals transplanted for the first time suffer a faster evolution of the tumor, shortened life span, and a diminution of spontaneous regressions if they have been irradiated prior to transplantation (400r whole body); and, 6. Resistance to tumor growth could not be transferred passively in serum of mice which had rejected the tumor.