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open access

Economic effects of projected climate change on outdoor recreation in Tennessee.

Description: Climate change projections from three General Circulation Models were used to adjust the temperature and precipitation in 2030 and 2080 in each of five ecological provinces in Tennessee to estimate the direct economic effects of the projected changes on recreation using the Tourism Climatic Index. The indirect effects on recreation were evaluated qualitatively, based on current demand for the unique values associated with current conditions. The results of the direct impact evaluation reveal th… more
Date: January 1, 2010
Creator: Hodges, Donald G.; Fogel, Jonah; Dale, Virginia H; Lannom, Karen O. & Tharp, M Lynn
open access

Laser Interactions in Nanomaterials Synthesis

Description: Laser interactions with materials have unique advantages to explore the rapid synthesis, processing, and in situ characterization of high quality and novel nanoparticles, nanotubes and nanowires. For example, laser vaporization of solids into background gases provides a wide range of processing conditions for the formation of nanomaterials by both catalyst-free and catalyst-assisted growth processes. Laser interactions with the growing nanomaterials provide remote in situ characterization of th… more
Date: January 1, 2010
Creator: Geohegan, David B.; Puretzky, Alexander A.; Rouleau, Christopher M.; Jackson, Jeremy Joseph; Eres, Gyula; Xiao, Kai et al.
open access

The Motif Tool Assessment Platform (MTAP) for Sequence-Based Transcription Factor Binding Site Prediction Tools.

Description: Predicting transcription factor binding sites (TFBS) from sequence is one of the most challenging problems in computational biology. The development of (semi-)automated computer-assisted prediction methods are needed to find TFBS over an entire genome, which is a first step in reconstructing mechanisms that controls gene activity. Bioinformatics journals continue to publish diverse methods for predicting TFBS on a monthly basis. To help practitioners in deciding which method to use to predict f… more
Date: January 2010
Creator: Quest, Daniel J. & Ali, Hesham
open access

Proceedings of the 6th Annual Workshop on Cyber Security and Information Intelligence Research: Cyber security and information intelligence challenges and strategies

Description: As our dependence on the cyber infrastructure grows more complex and more distributed, the systems that compose it become more prone to failures and exploitation. Intelligence refers to discrete or private information, which possess currency and relevance. The ability to abstract, evaluate, and understand such information underlies its accuracy and true value. The collection, analysis and utilization of information constitutes a business-, sociopolitical-, military-intelligence activity that ul… more
Date: January 1, 2010
Creator: Sheldon, Frederick T; Prowell, Stacy J; Krings, Axel & Abercrombie, Robert K
open access

Quality Assessment of Retinal Fundus Images using Elliptical Local Vessel Density

Description: Diabetic retinopathy is the leading cause of blindness in the Western world. The World Health Organisation estimates that 135 million people have diabetes mellitus worldwide and that the number of people with diabetes will increase to 300 million by the year 2025 (Amos et al., 1997). Timely detection and treatment for DR prevents severe visual loss in more than 50% of the patients (ETDRS, 1991). Through computer simulations is possible to demonstrate that prevention and treatment are relatively… more
Date: January 1, 2010
Creator: Giancardo, Luca; Meriaudeau, Fabrice; Karnowski, Thomas Paul; Chaum, Edward & Tobin Jr, Kenneth William
open access

Understanding enzyme catalysis using computer simulation

Description: Enzymes catalyze biochemical reactions with remarkable specificity and efficiency, usually under physiological conditions. Computer simulation is a powerful tool for understanding enzyme catalytic mechanisms, particularly in cases where standard experimental techniques may be of limited utility. Here, we present an overview of the application of computer simulation techniques to understanding enzyme catalytic mechanisms. Examples using quantum chemical methods, as well as combined quantum mecha… more
Date: January 1, 2010
Creator: Parks, Jerry M; Imhof, Petra & Smith, Jeremy C
open access

Wind Power: How Much, How Soon, and At What Cost?

Description: The global wind power market has been growing at a phenomenal pace, driven by favorable policies towards renewable energy and the improving economics of wind projects. On a going forward basis, utility-scale wind power offers the potential for significant reductions in the carbon footprint of the electricity sector. Specifically, the global wind resource is vast and, though accessing this potential is not costless or lacking in barriers, wind power can be developed at scale in the near to mediu… more
Date: January 1, 2010
Creator: Wiser, Ryan H & Hand, Maureen
open access

THE ROLE FUNGI AND YEAST IN MONITORED NATURAL ATTENUATION

Description: Fungi and yeast have been characterized as important components in the bioremediation of organic contaminants in soil and water including polyaromatic hydrocarbons (PAHs); however, research into their ability to metabolize these compounds in extreme environments has been limited. In this work forty-three fungi and yeasts were isolated from a PAH-contaminated sludge waste lagoon in Poland. The lagoon was part of a monitored natural attenuation (MNA) study where natural reduction of PAHs and asso… more
Date: January 26, 2010
Creator: Brigmon, R.; Abe, M.; Johnson, B.; Simpson, W. & Mckinsey, P.
open access

Design of Genomic Signatures of Pathogen Identification & Characterization

Description: This chapter will address some of the many issues associated with the identification of signatures based on genomic DNA/RNA, which can be used to identify and characterize pathogens for biodefense and microbial forensic goals. For the purposes of this chapter, we define a signature as one or more strings of contiguous genomic DNA or RNA bases that are sufficient to identify a pathogenic target of interest at the desired resolution and which could be instantiated with particular detection chemis… more
Date: February 9, 2010
Creator: Slezak, T.; Gardner, S.; Allen, J.; Vitalis, E. & Jaing, C.
open access

Conservation Laws for Coupled Hydro-mechanical Processes in Unsaturated Porous Media: Theory and Implementation

Description: We develop conservation laws for coupled hydro-mechanical processes in unsaturated porous media using three-phase continuum mixture theory. From the first law of thermodynamics, we identify energy-conjugate variables for constitutive modeling at macroscopic scale. Energy conjugate expressions identified relate a certain measure of effective stress to the deformation of the solid matrix, the degree of saturation to the matrix suction, the pressure in each constituent phase to the corresponding i… more
Date: February 19, 2010
Creator: Borja, R. I. & White, J. A.
open access

TOXNET and Beyond - Using the NLMs Environmental Health and Toxicology Portal-February

Description: The purpose of this training is to familiarize participants with reliable online environmental health and toxicology information, from the National Library of Medicine and other reliable sources. Skills and knowledge acquired in this training class will enable participants to access, utilize, and refer others to environmental health and toxicology information.
Date: February 24, 2010
Creator: Templin-Branner, W.
open access

Tumor Engineering: The Other Face of Tissue Engineering

Description: Advances in tissue engineering have been accomplished for years by employing biomimetic strategies to provide cells with aspects of their original microenvironment necessary to reconstitute a unit of both form and function for a given tissue.We believe that the most critical hallmark of cancer is loss of integration of architecture and function; thus, it stands to reason that similar strategies could be employed to understand tumor biology. In this commentary, we discuss work contributed by Fis… more
Date: March 9, 2010
Creator: Ghajar, Cyrus M & Bissell, Mina J
open access

Development of Glass Matrices for HLW Radioactive Wastes

Description: Vitrification is currently the most widely used technology for the treatment of high level radioactive wastes (HLW) throughout the world. Most of the nations that have generated HLW are immobilizing in either borosilicate glass or phosphate glass. One of the primary reasons that glass has become the most widely used immobilization media is the relative simplicity of the vitrification process, e.g. melt waste plus glass forming frit additives and cast. A second reason that glass has become widel… more
Date: March 18, 2010
Creator: Jantzen, Carol M.
open access

The Docs: A Graphic Novel

Description: "The Docs is the story of four Navy Corpsmen deployed to Iraq. While some events in the novel are specific to Operation Iraqi Freedom, this graphic novel is not intended to depict any specific time period or conflict. Rather, it represents a more general view of military life within a combat zone. The intent is to highlight challenges faced by Corpsmen in all wars. The commitment of Corpsmen to meeting these challenges is, like the story itself, timeless" (p. 5).
Date: April 2010
Creator: United States. The Naval Health Research Center.
open access

Hydrogeophysics

Description: Developing a predictive understanding of subsurface flow and transport is complicated by the disparity of scales across which controlling hydrological properties and processes span. Conventional techniques for characterizing hydrogeological properties (such as pumping, slug, and flowmeter tests) typically rely on borehole access to the subsurface. Because their spatial extent is commonly limited to the vicinity near the wellbores, these methods often can not provide sufficient information to de… more
Date: April 1, 2010
Creator: Hubbard, S. S. & Linde, N.
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