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50 Years Later: Women, Work & the Work Ahead

Description: Infographic commemorating the 50th anniversary of the American Women Report by outlining statistics and major events related to women's education and participation in the workforce from 1963 to 2012.
Date: 2012
Creator: United States. Women's Bureau.

2011 DOE Occupational Radiation Exposure Summary poster

Description: This poster graphically presents data pertaining to occupational radiation exposure in terms of total effective dose (TED), primarily, but also collective dose and average measureable dose.
Date: December 12, 2012
Creator: Oak Ridge Associated Universities

Alternations of Structure and Functional Activity of Below Ground Microbial Communities at Elevated Atmospheric Carbon Dioxide

Description: The global atmospheric concentration of CO2 has increased by more than 30percent since the industrial revolution. Although the stimulating effects of elevated CO2 (eCO2) on plant growth and primary productivity have been well studied, its influences on belowground microbial communities are poorly understood and controversial. In this study, we showed a significant change in the structure and functional potential of soil microbial communities at eCO2 in a grassland ecosystem, the BioCON (Biodive… more
Date: May 17, 2010
Creator: He, Zhili; Xu, Meiying; Deng, Ye; Kang, Sanghoon; Wu, Liyou; Van Nostrand, Joy D. et al.

Analysis of a US Department of Energy Emergent Technologies Cohort

Description: As a major user of engineered nanoparticles, the U.S. Department of Energy (DOE) uses various methods to monitor the health of emergent technologies workers (ETW) who handle or could potentially be exposed to unbound engineered nanoparticles (UNP). Using data from DOE’s Illness and Injury Surveillance Program (IISP), Oak Ridge Associated Universities (ORAU) created a registry of ETWs. IISP currently tracks 125,000 workers at 14 DOE facilities. Workers in IISP, who were classified as ETWs, were … more
Date: December 12, 2012
Creator: Strader, Cliff; Ellis, Elizabeth; Barrie, Martin D; Tankersley, William & Wallace, Phil

Durability of Polymeric Encapsulation Materials for Concentrating Photovoltaic Systems [Poster]

Description: Polymeric encapsulation materials are typically used in concentrating photovoltaic (CPV) modules to protect the cell from the field environment. Because it is physically located adjacent to the cell, the encapsulation is exposed to a high optical flux, often including light in the ultraviolet (UV) and infrared (IR) wavelengths. The durability of encapsulants used in CPV modules is critical to the technology, but is presently not well understood. This work seeks to identify the appropriate mater… more
Date: February 1, 2011
Creator: Miller, D. C.; Kempe, M. D.; Araki, K.; Kennedy, C. E. & Kurtz, S. R.

Effect of Increasing Nitrogen Deposition on Soil Microbial Communities

Description: Increasing nitrogen deposition, increasing atmospheric CO2, and decreasing biodiversity are three main environmental changes occurring on a global scale. The BioCON (Biodiversity, CO2, and Nitrogen) ecological experiment site at the University of Minnesota's Cedar Creek Ecosystem Science Reserve started in 1997, to better understand how these changes would affect soil systems. To understand how increasing nitrogen deposition affects the microbial community diversity, heterogeneity, and function… more
Date: May 17, 2010
Creator: Xiao, Shengmu; Xue, Kai; He, Zhili; VanNostrand, Joy D.; Liu, Jianshe; Hobbie, Sarah E. et al.

Effectiveness of Family Planning Methods

Description: Single page chart with graphical information on a variety of contraception methods and their percentage of effectiveness.
Date: 2011~
Creator: United States. Department of Health and Human Services, Centers for Disease Control and Prevention

Effects of experimental warming and clipping on metabolic change of microbial community in a US Great Plains tallgrass prairie

Description: While more and more studies are being conducted on the effects of global warming, little is known regarding the response of metabolic change of whole soil microbial communities to this phenomenon. In this study, functional gene changes at the mRNA level were analyzed by our new developed GeoChip 3.0. Soil samples were taken from a long-term climate warming experiment site, which has been conducted for ~;;8 years at the Kessler Farm Field Laboratory, a 137.6-ha farm located in the Central Redbed… more
Date: May 17, 2010
Creator: Xie, Jianping; Liu, Xinxing; Liu, Xueduan; Nostrand, Joy D. Van; Deng, Ye; Wu, Liyou et al.

Functional Ecological Gene Networks to Reveal the Changes Among Microbial Interactions Under Elevated Carbon Dioxide Conditions

Description: Biodiversity and its responses to environmental changes is a central issue in ecology, and for society. Almost all microbial biodiversity researches focus on species richness and abundance but ignore the interactions among different microbial species/populations. However, determining the interactions and their relationships to environmental changes in microbial communities is a grand challenge, primarily due to the lack of information on the network structure among different microbial species/p… more
Date: May 17, 2010
Creator: Deng, Ye; Zhou, Jizhong; Luo, Feng; He, Zhili; Tu, Qichao & Zhi, Xiaoyang

HuMiChip: Development of a Functional Gene Array for the Study of Human Microbiomes

Description: Microbiomes play very important roles in terms of nutrition, health and disease by interacting with their hosts. Based on sequence data currently available in public domains, we have developed a functional gene array to monitor both organismal and functional gene profiles of normal microbiota in human and mouse hosts, and such an array is called human and mouse microbiota array, HMM-Chip. First, seed sequences were identified from KEGG databases, and used to construct a seed database (seedDB) c… more
Date: May 17, 2010
Creator: Tu, Q.; Deng, Ye; Lin, Lu; Hemme, Chris L.; He, Zhili & Zhou, Jizhong

Hydrogel Tracer Beads: The Development, Modification, and Testing of an Innovative Tracer for Better Understanding LNAPL Transport in Karst Aquifers

Description: The goal of this specific research task is to develop proxy tracers that mimic contaminant movement to better understand and predict contaminant fate and transport in karst aquifers. Hydrogel tracer beads are transported as a separate phase than water and can used as a proxy tracer to mimic the transport of non-aqueous phase liquids (NAPL). They can be constructed with different densities, sizes & chemical attributes. This poster describes the creation and optimization of the beads and the … more
Date: January 1, 2012
Creator: Amanda Laskoskie, Harry M. Edenborn, and Dorothy J. Vesper

Identification of Small RNAs in Desulfovibrio vulgaris Hildenborough

Description: Desulfovibrio vulgaris is an anaerobic sulfate-reducing bacterium capable of facilitating the removal of toxic metals such as uranium from contaminated sites via reduction. As such, it is essential to understand the intricate regulatory cascades involved in how D. vulgaris and its relatives respond to stressors in such sites. One approach is the identification and analysis of small non-coding RNAs (sRNAs); molecules ranging in size from 20-200 nucleotides that predominantly affect gene regulati… more
Date: May 17, 2010
Creator: Burns, Andrew; Joachimiak, Marcin; Deutschbauer, Adam; Arkin, Adam & Bender, Kelly

In silico discovery of the dormancy regulons in a number of Actinobacteria genomes

Description: Mycobacterium tuberculosis is a dangerous Actinobacteria infecting nearly one third of the human population. It becomes dormant and phenotypically drug resistant in response to stresses. An important feature of the M. tuberculosis pathogenesis is the prevalence of latent infection without disease, making understanding of the mechanisms used by the bacteria to exist in this state and to switch to metabolically active infectious form a vital problem to consider. M. tuberculosis dormancy is regula… more
Date: November 16, 2010
Creator: Gerasimova, Anna; Dubchak, Inna; Arkin, Adam & Gelfand, Mikhail

Investigating the role of CheA-3 in Dusulfovibrio Vulgaris Hildenborough

Description: Multiple sets of chemotaxis genes including three cheA homologs were identified in the genome sequence of the anaerobic bacterium Desulfovibrio vulgaris Hildenborough. Each CheA is a histidine kinase (HK) and part of a two component signal transduction system. Knock out mutants in the three cheA genes were created using single cross-over homologous recombination insertion. We studied the phenotypes of the cheA mutants in detail and discovered that ?cheA-3 has a non swarming/swimming phenotype b… more
Date: May 22, 2010
Creator: Ray, Jayashee; Keller, Kimberley; Krierim, Bernhard; Auer, Manfred; Keasling, Jay; Wall, Judy et al.

Investigation of the carbon dioxide sorption capacity and structural deformation of coal

Description: Due to increasing atmospheric CO2 concentrations causing the global energy and environmental crises, geological sequestration of carbon dioxide is now being actively considered as an attractive option to mitigate greenhouse gas emissions. One of the important strategies is to use deep unminable coal seams, for those generally contain significant quantities of coal bed methane that can be recovered by CO2 injection through enhanced coal bed natural gas production, as a method to safely store CO2… more
Date: January 1, 2010
Creator: Hur, Tae-Bong; Fazio, James; Romanov, Vyacheslav & Harbert, William

Mapping the Two-component Regulatory Networks in Desulfovibrio vulgaris

Description: D. vulgaris Hildenborough has 72 response regulators. The Desulfovibrio are sulfate reducing bacteria that are important in the sulfur and carbon cycles in anoxic habitats. Its large number of two componenent systems are probably critical to its ability to sense and respond to its environment. Our goal is to map these RRs to the genes they regulate using a DNA-affinity-purification-chip (DAP-chip) protocol. First target determined usuing EMSA. A positive target was determined for as many RRs as… more
Date: May 17, 2010
Creator: Rajeev, Lara; Luning, Eric; Dehal, Paramvir; Joachimiak, Marcin & Mukhopadhyay, Aindrila

Microarray-based analysis of survival of soil microbial community during ozonation

Description: A 15 h ozonation was performed on bioremediated soil to remove recalcitrant residual oil. To monitor the survival of indigenous microorganisms in the soil during in-situ chemical oxidation(ISCO) culturing and a functional genearray, GeoChip, was used to examine the functional genes and structure of the microbial community during ozonation (0h, 2h, 4h, 6h, 10hand15h). Breakthrough ozonation decreased the population of cultivable heterotrophic bacteria by about 3 orders of magnitude. The total fu… more
Date: May 17, 2010
Creator: Wang, Jian; Van Nostrand, Joy D.; He, Zhili; Wu, Liyou; Deng, Ye; Zhang, Xu et al.

New National Wind Potential Estimates for Modern and Near-Future Turbine Technologies

Description: Recent advancements in utility-scale wind turbine technology and pricing have vastly increased the potential land area where turbines can be deployed in the United States. This presentation quantifies the new developable land potential (e.g., capacity curves), visually identifies new areas for possible development (e.g., new wind resource maps), and begins to address deployment barriers to wind in new areas for modern and future turbine technology.
Date: January 1, 2014
Creator: Roberts, J. O.

Phylogenetic Analysis of Shewanella Strains by DNA Relatedness Derived from Whole Genome Microarray DNA-DNA Hybridization and Comparison with Other Methods

Description: Phylogenetic analyses were done for the Shewanella strains isolated from Baltic Sea (38 strains), US DOE Hanford Uranium bioremediation site [Hanford Reach of the Columbia River (HRCR), 11 strains], Pacific Ocean and Hawaiian sediments (8 strains), and strains from other resources (16 strains) with three out group strains, Rhodopseudomonas palustris, Clostridium cellulolyticum, and Thermoanaerobacter ethanolicus X514, using DNA relatedness derived from WCGA-based DNA-DNA hybridizations, sequenc… more
Date: May 17, 2010
Creator: Wu, Liyou; Yi, T. Y.; Van Nostrand, Joy & Zhou, Jizhong

Rapid Field Measurement of Dissolved Inorganic Carbon Based on CO{sub 2} Analysis

Description: Dissolved inorganic carbon (DIC) is commonly measured in water and is an important parameter for understanding carbonate equilibrium, carbon cycling, and water-rock interaction. While accurate measurements can be made in the analytical laboratory, we have developed a rapid, portable technique that can be used to obtain accurate and precise data in the field as well.
Date: January 1, 2012
Creator: VESPER, DJ, Edenborn, Harry

Reference set of regulons in Desulfovibrionales inferred by comparative genomics approach

Description: in this study, we carried out large-scale comparative genomics analysis of regulatory interactions in Desulfovibrio vulgaris and 12 related genomes from Desulfovibrionales order using our recently developed web server RegPredict (http://regpredict.lbl.gov). An overall reference collection of 26 Desulfovibrionales regulogs can be accessed through RegPrecise database (http://regpredict.lbl.gov).
Date: November 15, 2010
Creator: Kazakov, Alexey E.; Rodionov, Dmitry A.; Price, Morgan N.; Arkin, Adam P.; Dubchak, Inna & Novichkov, Pavel S.

Regulon inference without arbitrary thresholds: three levels of sensitivity

Description: Reconstruction of transcriptional regulatory networks is one of the major challenges facing the bioinformatics community in view of constantly growing number of complete genomes. The comparative genomics approach has been successfully used for the analysis of the transcriptional regulation of many metabolic systems in various bacteria taxa. The key step in this approach is given a position weight matrix, find an optimal threshold for the search of potential binding sites in genomes. In our prev… more
Date: November 15, 2010
Creator: Dubchak, Pavel Novichkov, Elena Stavrovskaya, Dmitry Rodionov, Andrey Mironov, Inna; Rodionov, Dmitry; Mironov, Andrey; Dubchak, Inna & Novichkov, P.S.

The Role of the Tetraheme Cytochrome c3 in Desulfovibrio vulgaris Hildenborough Metabolism

Description: The role of tetraheme cytochrome c3 (CycA) in the metabolism of the sulfate-reducing bacterium Desulfovibrio vulgaris Hildenborough (DvH) was investigated by deletion of the cycA gene using a marker-exchange deletion strategy. A highly abundant periplasmic cytochrome, CycA has the important function of transferring electrons from periplasmic hydrogenases (Hyd, Hyn, Hys) to transmembrane complexes which transport the electrons to the cytoplasm where sulfate is reduced. Previous studies have indi… more
Date: May 17, 2010
Creator: Semkiw, Elizabeth; Zane, Grant & Wall, Judy
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