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Abscopal Effects of Localized Irradiation by Accelerator Beams

Description: The aim of this series of experiments was to evaluate the existence of abscopal effects of irradiation. No attempt was made towards the elucidation of mechanisms. Very early in the history of radiological research it was noticed radiation produces both local and general effects involving the entire body. Gauss and Lembcke introduced the term "Roentgenkater" (radiation sickness). They ascribed these "General Effects" to the circulation of toxic substances released from cells that disintegrated f… more
Date: February 1, 1963
Creator: Jansen, C. R.; Bond, V. P.; Rai, K. R. & Lippincott, S. W.
Item Type: Refine your search to only Report
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Adaptation of a Commercial Counter X-Ray Diffractometer for Investigations to 3000°C

Description: The rapid advances in many technologically important areas have not only served to accentuate the increased demands for high temperature metals and ceramics but have necessitated a more through knowledge of their physical properties when exposed to high temperature service. Toward this latter end, the use of X-ray diffraction has proved an invaluable tool in providing data of regions of thermal stability, expansion coefficients, solid solubility limits, and phase transformations by direct exami… more
Date: March 12, 1963
Creator: LaPalca, Samuel; Farber, Gerald & Adler, George
Item Type: Refine your search to only Report
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Adenosinetriphosphate Cleavage During the G-Actin to F-Actin Transformation and the Binding of Adenosinetriphosphate to F-Actin

Description: Since the discovery of the Straub and Feuer as well as Laki et al. that ATP bound to G-actin is transformed to ADP and inorganic phosphate during polymerization of actin (1, 2), it has become increasingly clear that the chemical changes in the nucleotide are related to the change in the physical state of the protein. Barany, Biro, Molnar and Straub have shown that highly purified actin preparation free of any enzyme which would use ATP, ADP or AMP as a substrate still catalyze the breakdown of … more
Date: October 15, 1963
Creator: Barany, M.; Koshland, D. E., Jr.; Springhorn, S. S.; Finkleman, F. & Theratil-Anthony, T.
Item Type: Refine your search to only Report
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AGS Performance and Plans

Description: The scope of the AGS complex has expanded rapidly during the three years since an accelerated beam was first obtained. Demand for research time far exceeds the amount available although facilities have been much increased. At the same time, experiments are being designed which are more complicated than previous ones and which make more stringent demands on the accelerator and on its auxiliary equipment. There is a continuous trend of experiments to particle beams of greater momentum, as the exp… more
Date: October 15, 1963
Creator: Green, G. K.
Item Type: Refine your search to only Report
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Alternating Gradient Magnets

Description: The angle by which a magnet deflects the trajectory of a particle in the x-z plane is proportional to the integral [integral not transcribed] taken over the trajectory wherever B≠0. Alternating gradient focusing is achieved by designing magnets so that I=I(x) varies linearly with x over a suitable x interval. Usually this is done by shaping the poles to give a linear variation of By with x while keeping the length of the magnet constant for different x. Certain advantaged may be gained by varyi… more
Date: March 3, 1963
Creator: Beth, R. A.
Item Type: Refine your search to only Report
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Antibody Formation by Transplanted Bone Marrow, Spleen, Lymph Node and Thymus Cells in Irradiated Recipients

Description: The role of the marrow as a site for antibody formation has been considered for many years. In 1912 Ludke reported the appearance of antibody in cultures of marrow cells obtained from previously immunized rabbits. Specific agglutinins for killed typhoid bacilli and lysins for ox red cells and sheep red cells were detected in the culture media 2 to 5 days later. However, the cultured cells failed to produce antibody when these antigens were added to the media. Similar findings by Reiter, Przygod… more
Date: February 25, 1963
Creator: Stoner, Richard D. & Bond, Victor P.
Item Type: Refine your search to only Report
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Automatic Bubble Density Measurement with the Hough-Powell System

Description: The Brookhaven Bubble Chamber Group is developing a Hough-Powell fast analysis system (HPD)1 for bubble chamber photographs. High precision measurements are made with a computer controlled flying spot digitizer. We are currently testing the track selection programs for the system. We have just completed a study of a method for automatic bubble density measurements.
Date: November 18, 1963
Creator: Strand, R. C. & Webre, N.W.
Item Type: Refine your search to only Report
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Beam Separators for Bev Particles

Description: The problem of separation of beams of particles of different masses but of the same momentum at Bev energies is the subject of a great deal of study at several high energy laboratories. In this note we shall describe the problem and tabulate a few of the cogent parameters. Frequently the student of high energy interactions is faced with a beam of miscellaneous particles coming from an accelerator. By standard techniques this beam can be rendered approximately parallel and an inch or so in diame… more
Date: January 22, 1963
Creator: Blewett, J. P.
Item Type: Refine your search to only Report
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Bromine Exchange in Graphite-Bromine Lamellar Compounds

Description: A kinetic study of the exchange of normal and radioactive bromine in graphite-bromine lamellar compounds has been made at temperatures of 30° to 50°C. Natural and synthetic graphite powders were investigated. Two alternative mechanisms for the exchange, volume diffusion and surface exchange, were considered. The data were in better agreement with the diffusion mechanism. Diffusion coefficients of 10 -9 to 10 -8 cm2/sec and an activation energy of 11 to 14 kcal/mole were calculated for the natur… more
Date: February 25, 1963
Creator: Aronson, Seymour
Item Type: Refine your search to only Report
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The Calculation of Zero-Point Energies of Molecules by Perturbation Methods

Description: Two methods are proposed for calculating zero-point energies of molecules. The first makes use of the fact that one can easily write down the quantum mechanical Hamiltonian for a vibration system. The zero-point energy can then be obtained by a perturbation scheme without solving the secular equation. The second method requires a knowledge of the normal modes and frequencies of a reference molecule, but then enables one to calculate isotope effects by a perturbation scheme. The methods are appl… more
Date: February 1963
Creator: Wolfsberg, Max
Item Type: Refine your search to only Report
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Cell Population Kinetics of an Osteogenetic Tissue, I

Description: Cell proliferation on the actively growing periosteal surface of the femur of rabbits aged two weeks, has been investigated using autoradiographic techniques. Injections of tritiated glycine and tritiated thymidine were given simultaneously and the animals sacrificed at intervals from one hour to 5 days after injection. The glycine labelled the position of the bone surface at the time of injection and the thymidine labelled the cells which were synthesizing DNA . The rate of increase in the cel… more
Date: March 12, 1963
Creator: Maureen, Owen
Item Type: Refine your search to only Report
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Cell Population Kinetics of an Osteogenetic Tissue, II

Description: A study of the cell kinetics on the actively growing periosteal surface of the femur of rabbits ages two weeks has been continues. A single injection of tritiated thymidine was given and the rabbits killed from one hour to four days after injection. The grain count spectra of the different cell types, pre-osteoblast, osteoblast and osteocyte, have been compared at different times after injection. The results showed evidence for the uptake of thymidine in nuclei which is not associated with cell… more
Date: March 12, 1963
Creator: Owen, Maureen & Pherson, Sheila Mac
Item Type: Refine your search to only Report
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The Cellular Differences Between Acute and Chronic Neutron and Gamma Ray Irradiation in Mice

Description: It has been well established that even small doses of radiation will shorten life expectancy of animals, and that in general the causes of death are the same for the irradiated as for the normal animals. When x or γ rays are compared with neutrons in their ability to shorten the life span, some interesting differences appear. All available data from different laboratories on the shortening of the life span by x or γ on the one hand and neutrons on the other, have been compared. In spite of the … more
Date: November 3, 1963
Creator: Curtis, H. J.; Tilley, J & Crowley, C.
Item Type: Refine your search to only Report
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Chronic Excess Salt Consumption as an Etiologic Factor in Human Hypertension

Description: Since 1940 it has been known that extra salt (i.e. sodium chloride) facilitated the development of experimental hypertension induced by various sterols; subsequently hypertension was induced by desoxycorticosterone acetate plus sodium chloride; then hypertension was produced by using hypertonic saline as the sole source of liquid; and finally, in 1953, Menesly and his associates reported that chronic ingestion of excess dietary salt alone would produce hypertension in rats. Furthermore, in conf… more
Date: February 1, 1963
Creator: Dahl, Lewis K.
Item Type: Refine your search to only Report
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Cobalt-60 Bulk Grain Irradiator: Study Report

Description: Report issued by the Brookhaven National Laboratory discussing bulk grain irradiators. As stated in the abstract, "this report presents the results of a study to conceive, evaluate, review and estimate costs for a number of suitable designs for a Cobalt-60 Bulk Grain Irradiator; select a preferred type; and establish required criteria for future detail design and construction of the selected concept" (p. ii). This report includes tables, and illustrations.
Date: June 30, 1963
Creator: Brookhaven National Laboratory
Item Type: Refine your search to only Report
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Crystal Structure of a Sodium Cobalt Molybdate

Description: The cobalt and molybdenum positions had been derived from a three-dimensional Patterson function based on complete data out to λ-1 sin θMo≈ 1. From the separation of the separation of the Mo atoms it was thought that the structure contained free, unlinked MoO4 -2 ions, and this, together with the observed density and analyses for Co and Mo, suggested that the composition was probably Co2(MoO4)3. The paucity of structural information on complex oxide systems and the interesting properties, both … more
Date: February 25, 1963
Creator: Ibers, James A. & Smith, G. W.
Item Type: Refine your search to only Report
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Cytochemistry of Delayed Radionecrosis of the Murine Spinal Cord

Description: In the vast field of radiation pathology we find pathologists, anatomists, and even physiologists busily at work, but the radiobiologist is conspicuously absent, although, according to Zirkle (1959), this field is clearly within his domain. Perhaps it is wise to take this broad hint of the scientifically so well equipped radiobiologist and to stay clear from an area in which an incalculable array of variables makes clearcut experimentation a hopeless venture, a priori. Perhaps it would be bette… more
Date: October 15, 1963
Creator: Zeman, Wolfgang
Item Type: Refine your search to only Report
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Determination of the Single Interstitial Migration Energy From Stored Energy and Thermal Resistivity Changes in Irradiated Graphite

Description: The model used to evaluate the single interstitial migration energy from property changes due to interstitials is extended to account for vacancy contributions. The annealing function obtained can be used to determine the relative contributions of the defects and is sufficiently sensitive to distinguish vacancy effects that are an order of magnitude less than interstitial effects. Application of the model to stored energy and thermal resistivity data yields the same values of the activation ene… more
Date: March 26, 1963
Creator: Schweitzer, Donald G.
Item Type: Refine your search to only Report
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Di-Interstitial Annealing During the First Neutron Irradiation of Graphite: The Mobility of C2

Description: Radiation and annealing mechanisms for dimensional and c-axis changes in which the di-interstitial can be mobile at any or all temperatures above absolute zero are shown to be concordant with earlier work used to determine the migration energy energy of single interstitials and the absolute rate of displacing atoms in graphite. The mechanisms account for the stability of c-axis and dimensional changes with time in the absence of irradiation and with observed c-axis annealing at room temperature… more
Date: February 1, 1963
Creator: Schweitzer, Donals G.
Item Type: Refine your search to only Report
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Effect of Long-Range Interactions on Order

Description: Harrison and Paskin (HP) have calculated the ordering energy of β-CuZn using recent theoretical techniques of treating electron screening and Mott's polar model of an alloy. Good agreement is obtained between the calculated total energy of the order-disorder transformation and specific heat measurements. A consequence of the HP calculation is that the ordering energy is long-range and oscillates in sign. Walker and Keating recently measured the neutron diffuse scattering of β-CuZn above the cri… more
Date: December 24, 1963
Creator: Paskin, Arthur
Item Type: Refine your search to only Report
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The Effect of Mitotic Cycle Duration on Chromosome Breakage in Meristematic Cells of Pisum Sativum

Description: One of the more apparent differences between acute and chronic irradiation is that exposure in the former is generally confined to a small fraction of a single mitotic cycle while in the latter; exposure of mitotically active tissue usually involves at least several cycles. Because of this difference, the number of cells in each stage of interphase would be of primary importance in acute radiation experiments since radiosensitivity is not the same in the G1, S and G2 periods. The duration of th… more
Date: October 14, 1963
Creator: Van't Hof, J. & Sparrow, A. H.
Item Type: Refine your search to only Report
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The Effects of 2.0 BeV Protons in Mice

Description: The Brookhaven proton synchrotron (Cosmotron) is capable of accelerating protons to energies as high as 3.0 BeV. The biologic effects of particle bombardment at these energies have not been investigated but are of considerable radiobiologic interest. In addition, particle beams have long been discussed with regard to their potential usefulness in medical therapy, and actual clinical applications have been made, although at lower particle energies. Recent rapid advances in space technology have … more
Date: November 3, 1963
Creator: Jesseph, John E.; Moore, William H.; Bond, Victor P. & Lippincott, Stuart W.
Item Type: Refine your search to only Report
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The Effects of 250-kv X-Ray on the Dog's Pancreas: Morphological and Functional Changes

Description: Previous investigations that the pancreas is a radioresistant organ. Ivy in 1924 noted the presence of a fibrotic atrophic pancreas in a dog which had received one erythema dose to the epigastrium. Fisher in 1923 reported that four to five erythema doses delivered in a single application caused complete disappearance of the irradiated pancreatic remnant in about two months. These dogs died because of uncontrolled diabetes. One dog that received four erythema doses (possibly 200 r) was sacrifice… more
Date: February 1, 1963
Creator: Archamefau, John; Griem, Melvin & Harper, Paul
Item Type: Refine your search to only Report
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Effects of Chronic Excess Salt Ingestion: Possible Implications of the Accelerated Induction of Experimental Hypertension by 2,4-Dinitrophenol

Description: Recently, we reported that the administration of the thyroid hormone, L-triiodothyronine (T3), markedly accelerated the development of experimental hypertension associated with a high-salt intake in intact rate. Earlier, Selye and his associates and Masson, Corcoran, and Page has observed a similar effect from thyroxin in uninephrectomized salt-fed rats. We were aware of the fact that oxidative phosphorylation is uncoupled by the thyroid hormone and were intrigued by the possibility that such u… more
Date: October 14, 1963
Creator: Dahl, Lewis K.; Heine, Martha & Tassinari, Lorraine
Item Type: Refine your search to only Report
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