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open access

A determination of the spatial concordance between Lyme disease incidence and habitat probability of its primary vector Ixodes scapularis (black-legged tick)

Description: This article involves mapping the probability of occurrence that the disease vector exists in the environment, mapping the incidence of Lyme disease in the human population and examining the spatial concordance between the probability map and incidence map.
Date: November 1, 2014
Creator: Atkinson, Samuel F.; Sarkar, Sahotra; Avina, Aldo; Schuermann, Jim A. & Williamson, Phillip C.
open access

Arabidopsis Thaliana--Myzus Persicae Interaction: Shaping the Understanding of Plant Defense Against Phloem-Feeding Aphids

Description: This review article summarizes recent studies that have exploited the compatible interaction between Arabidopsis and the green peach aphid (GPA) to understand the molecular and physiological mechanisms utilized by plants to control aphid infestation, as well as genes and mechanisms that contribute to susceptibility.
Date: July 1, 2013
Creator: Louis, Joe & Shah, Jyoti
open access

Biochemical and molecular-genetic characterization of SFD1’s involvement in lipid metabolism and defense signaling

Description: Article describes study which sought to to determine if the dihydroxyacetone phosphate (DHAP) reductase activity and chloroplast localization are required for the Arabidopsis thaliana SFD1 (suppressor of fatty acid desaturase deficiency1) gene’s involvement in galactolipid metabolism and systemic acquired resistance (SAR) signaling.
Date: February 7, 2012
Creator: Lorenc-Kukula, Katarzyna; Chaturvedi, Ratnesh; Roth, Mary; Welti, Ruth & Shah, Jyoti
open access

Computational Identification of Amino-Acid Mutations That Further Improve the Activity of a Chalcone-Flavonone Isomerase From Glycine Max

Description: This article discusses a computational approach that combines multiple sequence alignment, positive selection detection, and molecular docking to identify and design beneficial amino-acid mutations that further improve the intramolecular-cyclization activity of a chalcone-flavonone isomerase from Glycine max (GmCHI).
Date: February 24, 2017
Creator: Yuan, Hui; Wu, Jiaqi; Wang, Xiaoqiang; Chen, Jiakuan; Zhong, Yang; Huang, Qiang et al.
open access

What makes species unique? The contribution of proteins with obscure features

Description: This article performs a comparative analysis of the predicted proteomes derived from 10 different sequenced genomes, including budding and fission yeast, worm, fly, mosquito, Arabidopsis, rice, mouse, rat, and human.
Date: June 27, 2006
Creator: Gollery, Martin; Harper, Jeffrey F.; Cushman, John; Mittler, Taliah; Girke, Thomas; Zhu, Jian-Kang et al.
open access

Cardiac and metabolic physiology of early larval zebrafish (Danio rerio) reflects parental swimming stamina

Description: Article describes experiment in which mature adult zebrafish (Danio rerio) were subjected to a swimming performance test that allowed separation into low swimming stamina or high swimming stamina groups in order to determine if inherited traits that support enhanced swimming stamina in offspring appear only in juveniles and/or adults, or if these traits actually appear earlier in the morphologically quite different larvae.
Date: February 24, 2012
Creator: Gore, Matthew & Burggren, Warren W.
open access

Identification of Novel Genomic Islands in Liverpool Epidemic Strain of Pseudomonas aeruginosa Using Segmentation and Clustering

Description: This article utilizes a recursive segmentation and cluster procedure presented as a genome-mining tool, GEMINI, to decipher genomic islands and understand their contributions to the evolution of virulence and antibiotic resistance in Pseudomonas aeruginosa.
Date: August 3, 2016
Creator: Jani, Mehul; Mathee, Kalal & Azad, Rajeev K.
open access

Breast Cancer Stem-Like Cells Are Inhibited by Diosgenin, a Steroidal Saponin, by the Attenuation of the Wnt β-Catenin Signaling via the Wnt Antagonist Secreted Frizzled Related Protein-4

Description: This article describes findings that demonstrate the affect of diosgenin (DG) on inhibiting the resilient breast cancer stem cells (CSCs) which could provide a benchmark for the development of DG-based therapies in breast cancer treatment.
Date: March 20, 2017
Creator: Bhuvanalakshmi, G.; Basappa; Rangappa, Kanchugarakoppal S.; Dharmarajan, Arunasalam; Sethi, Gautam; Kumar, Alan Prem et al.
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