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Ion exchanger in the brain: Quantitative analysis of perineuronally fixed anionic binding sites suggests diffusion barriers with ion sorting properties

Description: This article proposes that fixed charge-densities in the brain are involved in regulating ion mobility, the volume fraction of extracellular space and the viscosity of matrix components.
Date: December 1, 2015
Creator: Morawski, Markus; Reinert, Tilo; Meyer-Klaucke, Wolfram; Wagner, Friedrich E.; Tröger, Wolfgang; Reinert, Anja et al.
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Loitering at the hilltop on exterior domains

Description: In this article, the author proves the existence of an infinite number of radial solutions of Δu+f(u)=0 on the exterior of the ball of radius R>0 centered at the origin and f is odd with f<0 on (0,β), f>0 on (β,δ), and f≡0 for u>δ. The primitive F(u)=∫u0f(t)dt has a "hilltop" at u=δ which allows one to use the shooting method and ODE techniques to prove the existence of solutions.
Date: November 23, 2015
Creator: Iaia, Joseph A.
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Crystal structure of (3E,5E)-3,5-bis­[4-(di­ethyl­aza­nium­yl)benzyl­idene]-1-methyl-4-oxopiperidin-1-ium trichloride dihydrate: a potential biophotonic material

Description: Article provides a detailed description of the crystal structure of (3E,5E)-3,5-bis­­[4-(di­ethyl­aza­nium­yl)benzyl­­idene]-1-methyl-4-oxopiperidin-1-ium trichloride dihydrate
Date: November 21, 2015
Creator: Nesterov, Volodymyr V.; Zakharov, Lev N.; Nesterov, Vladimir N. & Shulaev, Vladimir
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Crystal structure of (3E,5E)-3,5-bis[4-(diethylazaniumyl)benzylidene]-1-methyl-4-oxopiperidin-1-ium trichloride dihydrate: a potential biophotonic material

Description: This article describes the crystal structure of the title compound, and examines application as an agent for locating cancer cells with two-photon excited fluorescence as as a potential agent for a photodynamic treatment of cancer. This article includes supporting information with computing details of the study.
Date: November 4, 2015
Creator: Nesterov, Volodymyr V.; Zakharov, Lev N.; Nesterov, Vladimir N. & Shulaev, Vladimir
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Targeting the PI3K/Akt signaling pathway in gastric carcinoma: A reality for personalized medicine?

Description: Article reviews the common dysregulation of phosphatidylinositol-3 kinases (PI3K)/Akt/mTOR pathway in gastric cancer (GC) and the various types of single or dual pathway inhibitors under development that might have a superior role in GC treatment.
Date: October 26, 2015
Creator: Singh, Shikha Satendra; Yap, Wei Ney; Arfuso, Frank; Kar, Shreya; Wang, Chao; Cai, Wanpei et al.
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Evaluating player task engagement and arousal using electroencephalography

Description: This paper from the 6th International Conference on Applied Human Factors and Ergonomics and the Affiliated Conference, AHFE 2015 conference proceedings coordinate task engagement data with arousal-valence data for application to expressive transformations to video game play in real time by tuning different performance parameters in an Engagement-Arousal rule system.
Date: October 23, 2015
Creator: McMahan, Timothy; Parberry, Ian & Parsons, Thomas D.
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Multireference Character for 4D Transition Metal-Containing Molecules

Description: This article proposes new criteria, namely T₁ ≥ 0.045, D₁ ≥ 0.120, and %TAE ≥ 10%, as a gauge for 4d transition metal-containing molecules to predic the possible need to employ multireference (MR) wave function-based methods to describe energetic and spectroscopic properties.
Date: October 14, 2015
Creator: Wang, Jiaqi; Manivasagam, Sivabalan & Wilson, Angela K.
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open access

Cancer-Related NEET Proteins Transfer 2Fe-2S Clusters to Anamorsin, a Protein Required for Cytosolic Iron-Sulfur Cluster Biogenesis

Description: This article reports the first physiological 2Fe-2S cluster acceptor for both NEET proteins as human Anamorsin (also known as cytokine induced apoptosis inhibitor-1; CIAPIN-1).
Date: October 8, 2015
Creator: Lipper, Colin H.; Paddock, Mark L.; Onuchic, José N.; Mittler, Ron; Nechushtai, Rachel & Jennings, Patricia A.
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