A novel statistical method for rare-variant association studies in general pedigrees
Description:
In this paper, the authors discuss a novel statistical method for rare-variant association studies in general pedigrees for quantitative traits. This method uses a retrospective view that treats the traits as fixed and the genotypes as random, which accounts for complex and undefined ascertainment of families.
Date:
October 18, 2016
Creator:
Zhu, Huanhuan; Wang, Zhenchuan; Wang, Xuexia & Sha, Qiuying