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open access

Erratum to: More Comprehensive Forensic Genetic Marker Analyses for Accurate Human Remains Identification Using Massively Parallel DNA Sequencing

Description: This article provides erratum for the article "More Comprehensive Forensic Genetic Marker Analyses for Accurate Human Remains Identification Using Massively Parallel DNA Sequencing," which incorrectly deleted an author from the author list.
Date: April 20, 2017
Creator: Ambers, Angie D.; Churchill, Jennifer D.; King, Jonathan L.; Stoljarova, Monika; Gill-King, Harrell; Assidi, Mourad et al.
open access

Interactions between mitoNEET and NAF-1 in cells

Description: This article uses yeast two-hybrid to demonstrate through vivo bimolecular fluorescence complementation (BiFC), direct coupling analysis (DCA), RNA-sequencing, ROS and iron imaging, and single and double shRNA lines with suppressed mNT, NAF-1 and mNT/NAF-1 expression, that mNT and NAF-1 directly interact in mammalian cells and could function in the same cellular pathway.
Date: April 20, 2017
Creator: Karmi, Ola; Holt, Sarah H.; Song, Luhua; Tamir, Sagi; Luo, Yuting; Bai, Fang et al.
open access

Dry Season Limnological Conditions and Basin Geology Exhibit Complex Relationships With δ¹³C and δ¹⁵N of Carbon Sources in Four Neotropical Floodplains

Description: This article assesses the potential for basin geology and local limnological conditions to predict stable carbon and nitrogen isotope values of six carbon sources at multiple locations in four Neotropical floodplain ecosystems (Paranaá , Pantanal, Araguaia, and Amazon).
Date: March 30, 2017
Creator: Alves, Gustavo H. Zaia; Hoeinghaus, David; Manetta, Gislaine I. & Benedito, Evanilde
open access

A Comparison of Least Squares Regression and Geographically Weighted Regression Modeling of West Nile Virus Risk Based on Environmental Parameters

Description: This article discusses the effectiveness of utilizing local spatial variations in environmental data to uncover the statistical relationships between West Nile Virus (WNV) risk and environmental factors.
Date: March 28, 2017
Creator: Kala, Abhishek K.; Tiwari, Chetan; Mikler, Armin R. & Atkinson, Samuel F.
open access

Breast Cancer Stem-Like Cells Are Inhibited by Diosgenin, a Steroidal Saponin, by the Attenuation of the Wnt β-Catenin Signaling via the Wnt Antagonist Secreted Frizzled Related Protein-4

Description: This article describes findings that demonstrate the affect of diosgenin (DG) on inhibiting the resilient breast cancer stem cells (CSCs) which could provide a benchmark for the development of DG-based therapies in breast cancer treatment.
Date: March 20, 2017
Creator: Bhuvanalakshmi, G.; Basappa; Rangappa, Kanchugarakoppal S.; Dharmarajan, Arunasalam; Sethi, Gautam; Kumar, Alan Prem et al.
open access

Novel transcriptome assembly and comparative toxicity pathway analysis in mahi-mahi (Coryphaena hippurus) embryos and larvae exposed to Deepwater Horizon oil

Description: This article establishes the de novo transcriptomic database from the embryos and larvae of mahi-mahi exposed to water accommodated fractions (HEWAFs) of two Deepwater Horizon oil types (weathered and source oil) in an effort to advance understanding of the molecular aspects involved during specific toxicity responses.
Date: March 15, 2017
Creator: Xu, Elvis Genbo; Mager, Edward M.; Grosell, Martin; Hazard, E. Starr; Hardiman, Gary & Schlenk, Daniel
open access

Computational Identification of Amino-Acid Mutations That Further Improve the Activity of a Chalcone-Flavonone Isomerase From Glycine Max

Description: This article discusses a computational approach that combines multiple sequence alignment, positive selection detection, and molecular docking to identify and design beneficial amino-acid mutations that further improve the intramolecular-cyclization activity of a chalcone-flavonone isomerase from Glycine max (GmCHI).
Date: February 24, 2017
Creator: Yuan, Hui; Wu, Jiaqi; Wang, Xiaoqiang; Chen, Jiakuan; Zhong, Yang; Huang, Qiang et al.
open access

Transgenic Switchgrass (Panicum Virgatum L.) Targeted for Reduced Recalcitrance to Bioconversion: A 2-Year Comparative Analysis of Field-Grown Lines Modified for Target Gene or Genetic Element Expression

Description: This article discusses the investigation of clones of plants representing independent transgenic events and their respective nontransgenic control lines for biomass yield, carbohydrate composition and recalcitrance to bioconversion via separate hydrolysis and fermentation to yield ethanol.
Date: February 20, 2017
Creator: Dumitrache, Alexandru; Natzke, Jace; Rodriguez, Miguel, Jr.; Yee, Kelsey L.; Thompson, Olivia A.; Poovaiah, Charleson R. et al.
open access

Phylogenetic analysis of eukaryotic NEET proteins uncovers a link between a key gene duplication event and the evolution of vertebrates

Description: This article describes the use of three members of the human NEET protein family (CISD1, mitoNEET; CISD2, NAF-1 or Miner 1; and CISD3, Miner2) as guides to conduct a phylogenetic analysis of eukaryotic NEET proteins and their evolution.
Date: February 16, 2017
Creator: Inupakutika, Madhuri A.; Sengupta, Soham; Nechushtai, Rachel; Jennings, Patricia A.; Onuchic, José N.; Azad, Rajeev K. et al.
open access

Evidence for the Involvement of Electrical, Calcium and ROS Signaling in the Systemic Regulation of Non-Photochemical Quenching and Photosynthesis

Description: Article presents study in which pulse amplitude-modulated Chl fluorescence imaging and surface electrical potential measurements accompanied by pharmacological treatments were employed to study stimuli-induced electrical signals in leaves from a broad range of plant species and in Arabidopsis thaliana mutants.
Date: February 10, 2017
Creator: Białasek, Maciej; Górecka, Magdalena; Mittler, Ron & Karpiński, Stanisław
open access

Spatial and Temporal Mapping of Key Lipid Species in Brassica napus Seeds

Description: This article describes the use of matrix-assisted laser/desorption ionization-mass spectrometry imaging (MALDI-MSI) to study the spatial distribution of two major lipid species, triacylglycerols and phosphatidylcholines.
Date: February 10, 2017
Creator: Woodfield, Helen K.; Sturtevant, Drew; Borisjuk, Ljudmilla; Munz, Eberhard; Guschina, Irina A.; Chapman, Kent D. et al.
open access

Lophozonia tree cavities used for nesting by Slender-billed Parakeets (Enicognathus leptorhynchus) in the central valley of southern Chile: a potentially vanishing keystone resource

Description: This article describes and quantifies characteristics of southern beech (Lophoonia obliqua) trees and their associated cavities used for nesting by Slender-billed Parakeets in the central valley of southern Chile.
Date: February 6, 2017
Creator: White, Thomas H., Jr. & Jiménez, Jaime E.
open access

Body shape differences in a pair of closely related Malawi cichlids and their hybrids: Effects of genetic variation, phenotypic plasticity, and transgressive segregation

Description: This article investigates the contributions of genetic and plastic components for differences in body shape in two species of Lake Malawi cichlids using wild-caught specimens and a common garden experiment.
Date: January 28, 2017
Creator: Husemann, Martin; Tobler, Michael; McCauley, Cagney; Ding, Baoqing & Danley, Patrick D.
open access

Wnt signaling in triple-negative breast cancer

Description: This review summarizes the involvement of dysregulated Wnt signaling in the progression of triple-negative breast cancer (TNBC) and TNBC stem cells, as well as the emerging therapies that are currently under investigation.
Date: January 24, 2017
Creator: Pohl, Sebastian Öther-Gee; Brook, N; Agostino, M.; Arfuso, Frank & Kumar, Alan Prem
open access

A chemical genetic screen uncovers a small molecule enhancer of the N-acylethanolamine degrading enzyme, fatty acid amide hydrolase, in Arabidopsis

Description: This article demonstrates the feasibility of using an unbiased chemical genetic approach to identify new pharmacological tools for manipulating FAAH- and NAE-mediated physiological processes in plants.
Date: January 23, 2017
Creator: Khan, Bibi Rafeiza; Faure, Lionel; Chapman, Kent D. & Blancaflor, Elison B.
open access

Mouse fat storage-inducing transmembrance protein 2 (FIT2) promotes lipid droplet accumulation in plants

Description: This article discusses the test of the function of FIT2 in plant cells by ectopically expressing mouse (Mus musculus) FIT2 in Nicotiana tabacum suspension-cultured cells, Nicotiana benthamiana leaves and Arabidopsis thaliana plants.
Date: December 2, 2016
Creator: Cai, Yingqi; McClinchie, Elizabeth; Price, Ann; Nguyen, Thuy N.; Gidda, Satinder K.; Watt, Samantha C. et al.
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