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open access

An UPLC-ESI-MS/MS Assay Using 6-Aminoquinolyl-N-Hydroxysuccinimidyl Carbamate Derivatization for Targeted Aminio Acid Analysis: Application to Screening of Arabidopsis thaliana Mutants

Description: This article presents a method that enables thirty-eight metabolites (proteinogenic amino acids and related compounds) to be analyzed, with an improved sensitivity of 1 to 5 orders of magnitude compared to existing methods.
Date: July 6, 2012
Creator: Salazar, Carolina; Armenta, Jenny M. & Shulaev, Vladimir
open access

Inhibition of STAT3 dimerization and acetylation by garcinol suppresses the growth of human hepatocellular carcinoma in vitro and in vivo

Description: Article on the inhibition of STAT3 dimerization and acetylation by garcinol suppresses the growth of human hepatocellular carcinoma in vitro and in vivo.
Date: March 21, 2014
Creator: Sethi, Gautam; Chatterjee, Snehajyoti; Rajendran, Peramaiyan; Li, Feng; Shanmugam, Muthu K.; Wong, Kwong Fai et al.
open access

Long-distance communication and signal amplication in systemic acquired resistance

Description: This review article summarizes the involvement and interaction between long-distance systemic acquired resistance (SAR) signals and details the recently discovered role of lysine catabolite pipecolic acid (Pip) in defense amplification and priming that allows plants to acquire immunity at the systemic level.
Date: February 22, 2013
Creator: Shah, Jyoti & Zeier, Jürgen
open access

Targeted inhibition of tumor proliferation, survival, and metastasis by pentacyclic triterpenoids: Potential role in prevention and therapy of cancer

Description: Article on the targeted inhibition of tumor proliferation, survival, and metastasis by pentacyclic triterpenoids and the potential role in prevention and therapy of cancer.
Date: July 28, 2012
Creator: Shanmugam, Muthu K.; Nguyen, An H.; Kumar, Alan Prem; Tan, Benny K-H & Sethi, Gautam
open access

Ursolic Acid Inhibits the Initiation, Progression of Prostate Cancer and Prolongs the Survival of TRAMP Mice by Modulating Pro-Inflammatory Pathways

Description: Article on ursolic acid inhibiting the initiation, progression of prostate cancer and prolonging the survival of TRAMP mice by modulating pro-inflammatory pathways.
Date: March 12, 2012
Creator: Shanmugam, Muthu K.; Ong, Tina H.; Kumar, Alan Prem; Chang, Kai Lun; Ho, Paul C.; Wong, Peter T. H. et al.
open access

Identification of cDNA clones encoding valosin-containing protein and other plant plasma membrane-associated proteins by a general immunoscreening strategy

Description: Article on the identification of cDNA clones encoding valosin-containing protein and other plant plasma membrane-associated proteins by a general immunoscreening strategy.
Date: May 1, 1995
Creator: Shi, Jinrui; Dixon, R. A.; Gonzales, Robert A.; Kjellbom, Per & Bhattacharyya, Madan Kumar
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