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1-Benzyl-3,5-bis(4-chlorobenzylidene)-piperidin-4-one

Description: The title compound, C₂₆H₂₁Cl₂NO, crystallizes with two symmetry-independent molecules in the asymmetric unit.
Date: May 16, 2011
Creator: Nesterov, Volodymyr V.; Sarkisov, Sergey S.; Shulaev, Vladimir & Nesterov, Vladimir N.
open access

3,5-Bis(4-chlorobenzylidene)-1-methyl-piperidin-4-one

Description: In the title molecule, C₂₀H₁₇Cl₂NO, the central heterocyclic ring adopts a flattened boat conformation.
Date: February 23, 2011
Creator: Nesterov, Volodymyr V.; Sarkisov, Sergey S.; Shulaev, Vladimir & Nesterov, Vladimir N.
open access

An anthraquinone derivative, emodin sensitizes hepatocellular carcinoma cells to TRAIL indced apoptosis through the induction of death receptors and downregulation of cell survival proteins

Description: Article on an anthraquinone derivative, emodin sensitizes hepatocellular carcinoma cells to TRAIL induced apoptosis through the induction of death receptors and downregulation of cell survival proteins.
Date: May 23, 2013
Creator: Subramaniam, Aruljothi; Loo, Ser Yue; Rajendran, Peramaiyan; Manu, Kanjoormana Aryan; Perumal, Ekambaram; Li, Feng et al.
open access

Antiviral Activity of Metal-Containing Polymers—Organotin and Cisplatin-Like Polymers

Description: This article examines the use of metal-containing polymers as a novel class of antivirals. Polymers containing platinum and to a lesser extent tin, have repeatedly demonstrated antitumor activity in vitro and in vivo against a variety of cell and tumor types. The mechanisms responsible for the antitumor activity include inducing a delay in cell proliferation and sister chromatid exchanges blocking tumor growth.
Date: May 27, 2011
Creator: Roner, Michael R.; Carraher, Charles E., Jr.; Shahi, Kimberly & Barot, Girish
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