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open access

Targeting the PI3K/Akt signaling pathway in gastric carcinoma: A reality for personalized medicine?

Description: Article reviews the common dysregulation of phosphatidylinositol-3 kinases (PI3K)/Akt/mTOR pathway in gastric cancer (GC) and the various types of single or dual pathway inhibitors under development that might have a superior role in GC treatment.
Date: October 26, 2015
Creator: Singh, Shikha Satendra; Yap, Wei Ney; Arfuso, Frank; Kar, Shreya; Wang, Chao; Cai, Wanpei et al.
open access

The Prognostic Value of the Stem-Like Group in Colorectal Cancer Using a Panel of Immunohistochemistry Markers

Description: This article examines the immunohistochemical expression profile of 18 markers, each representing a putative role in cancer development, in 493 primary colorectal carcinomas using tissue microarrays.
Date: March 26, 2015
Creator: Ong, Chee Wee; Chong, Pei Yi; McArt, Darragh G.; Chan, Jason Yongsheng; Tan, Hwee Tong; Kumar, Alan Prem et al.
open access

Ultra-Fast Alterations in mRNA Levels Uncover Multiple Players in Light Stress Acclimation in Plants

Description: This article contains RNA sequencing analysis of Arabidopsis thaliana plants subjected to light stress in order to identify and characterize rapid changes in the steady-state level of different transcripts in response to light stress.
Date: September 26, 2015
Creator: Suzuki, Nobuhiro; Devireddy, Amith R.; Inupakutika, Madhuri A.; Baxter, Aaron; Miller, Gad; Song, Luhua et al.
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