Identification of Glycine as the Factor in Peptone Which Induces Pleomorphism in Azotobacter Vinelandii
Description:
The rigid peptidoglycan layer of the cell wall is responsible for maintaining the structural integrity of bacteria. Antibiotics such as penicillin exert their anti-bacterial effect by inhibiting synthesis of peptodoglycan, and enzymes such as lysozyme destroy cell integrity by hydrolyzing specific bonds in the interior of this macromolecule. Defective cells can no longer withstand the high turgor pressure within the cell because they are no longer protected by a rigid wall and tend to become fr…
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Date:
December 1972
Creator:
Rosenthal, Raoul Simon