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  Partner: UNT Libraries
 Resource Type: Thesis or Dissertation
 Decade: 2010-2019
Genetic and Environmental Factors that Mediate Survival of Prolonged Oxygen Deprivation in the Nematode Caenorhabditis Elegans

Genetic and Environmental Factors that Mediate Survival of Prolonged Oxygen Deprivation in the Nematode Caenorhabditis Elegans

Date: August 2010
Creator: LaRue, Bobby Lee, Jr.
Description: Ischemic events of even a very short duration are not tolerated Ill in humans. The human cost of ischemia, when looked at as combined cardiovascular disease, dwarfs all other causes of death in the United States. Annually, CVD kills as many people in the US as does cancer, chronic lower respiratory disease, accidents, and diabetes mellitus combined. In 2005 (the latest year for which final statistics are available), CVD was responsible for 864,480 deaths or 35.3 percent of total deaths for the year. In my study, I have used the nematode Caenorhabditis elegans to determine genetic and environmental modulators of oxygen deprivation a key component of ischemia. I have found that animals with mutations in insulin like signaling pathways, neuronal function, electron transport chain components, germline function, and animals that are preconditioned by being raised on a diet of E. coli HT115 bacteria at 25°C have an enhanced ability to survive long-term (>72 hours) anoxia (<.005 kPa O2) at 20°C. The enhanced anoxia survival phenotype partially correlates with increased levels of carbohydrate stores in the nematodes. Suppression of this enhanced anoxia survival phenotype is possible by altering expression of the glycolytic enzyme glyceraldehyde-3-phosphate dehydrogenase, the FOXO transcription factor DAF-16, and ...
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Genetic Interest Assessment

Genetic Interest Assessment

Date: May 2013
Creator: Doughney, Erin
Description: Genetics is becoming increasingly integrated into peoples' lives. Different measures have been taken to try and better genetics education. This thesis examined undergraduate students at the University of North Texas not majoring in the life sciences interest in genetic concepts through the means of a Likert style survey. ANOVA analysis showed there was variation amongst the interest level in different genetic concepts. In addition age and lecture were also analyzed as contributing factors to students' interest. Both age and lecture were evaluated to see if they contributed to the interest of students in genetic concepts and neither showed statistical significance. The Genetic Interest Assessment (GIA) serves to help mediate the gap between genetic curriculum and students' interest.
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Gentrification in Oklahoma City:  Examining Urban Revitalization in Middle America

Gentrification in Oklahoma City: Examining Urban Revitalization in Middle America

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Date: August 2011
Creator: Petty, Clint C.
Description: Gentrification applies not only to the largest and oldest cities; it is a multi-scalar phenomenon playing out in smaller and less prominent settings as well. This study examines temporal changes in property values, demographic characteristics, and types of businesses in the central Oklahoma City area. A major urban revitalization project which began in 1993 created strong gentrification characteristics near the renewal's epicenter, the Bricktown entertainment district. Data suggest that several specific neighborhoods in the surrounding area exhibited rising property values, improving educational attainment rates, decreasing household sizes, and a shift toward cosmopolitan retail activity. While it is evident that Bricktown has been transformed, the socio-economic traits of surrounding neighborhoods have been altered by the ripple effects of urban renewal.
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Geoarchaeological Analysis of Two New Test Pits at the Dmanisi Site, Republic of Georgia

Geoarchaeological Analysis of Two New Test Pits at the Dmanisi Site, Republic of Georgia

Date: May 2013
Creator: Zack, Winston S.
Description: This thesis presents the results of geoarchaeological investigations conducted at two new test pits, M11 and M12, at the paleoanthropological site of Dmanisi during the 2012 field season. This research is important for understanding the site formation processes occurring along the north-south axis of the Dmanisi site and how that affects the chronostratigraphic sequence and interpretation of archaeological materials here. With these excavations we can build a stronger interpretation for how broader areas of this site formed and changed both geologically and archaeologically. The geologic results of this study indicate that changes in sediment deposition and development episodes can affect interpretations of how long these sediments accumulated, how likely bones are to preserve, as well as how secondary gravel deposition can influence several archaeological interpretations. The archaeological results suggest that there could have been changes in occupation intensity between the stratum A and B phases although different rates of sediment deposition and surface stability could affect such artifact accumulations. In addition, during the stratum B phase there appears to be little change in artifact procurement behaviors and reduction characteristics by these hominins. The overall results of this research indicate that geologic factors should be addressed and cautions should be taken ...
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A Geoarchaeological Investigation of Site Formation in the Animas River Valley at Aztec Ruins National Monument, NM

A Geoarchaeological Investigation of Site Formation in the Animas River Valley at Aztec Ruins National Monument, NM

Date: August 2010
Creator: Caster, Joshua
Description: This paper presents an investigation of sedimentary deposition, soil formation, and pedoturbation in the Animas River Valley to determine the provenience of archaeological deposits in an open field at Aztec Ruins National Monument, NM outside of the Greathouse complex. Four stratigraphic pedounits correlated with active fan deposition have been proposed for the lower terrace in the project area with only one of these units retaining strong potential for buried archaeological deposits from the Anasazi late Pueblo II/Pueblo III period. The distal fan on the lower terrace and the Animas River floodplain appear to show poor potential for archaeological deposits either due to shallow sediment overburden with historic disturbance or alluvial activity during or after occupation. Based on these findings, four other zones of similar fan development have been identified throughout the Animas Valley and are recommended for subsurface testing during future cultural resource investigations.
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Geographic Distance, Contact, and Family Perceptions of Quality Nursing Home Care

Geographic Distance, Contact, and Family Perceptions of Quality Nursing Home Care

Date: May 2010
Creator: Dillman, Jennifer L
Description: The effect of frequency of nursing home contact on family perceptions of quality care is the focus of this research. A family member characteristic, such as geographic distance from the nursing home, affects his or her frequency of contact with the nursing home. Frequency of contact, in turn, affects family perceptions of the care his or her loved one receives in the nursing home. The theoretical framework for this study is based on Allport's intergroup contact theory, which posits that when four contact conditions - institutional support, equal status, common goals, and intergroup cooperation - are present in an intergroup situation, a reduction in anxiety between groups is likely to occur. Regression analysis tested the stated hypotheses using survey data collected from 275 family members of residents in 10 Dallas-Ft. Worth area nursing homes. This study is among the first to quantify family geographic distance, finding that family geographic distance is a significant negative predictor of nursing home contact. Additionally, results build on Allport's theory by extending its' usefulness to nursing home organizations in two distinct ways. First, findings support Allport's premise that contact alone between groups - i.e., family members and nursing home staff - is insufficient for increasing ...
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Geography of Hiv Infection Among Adults Aged 50 Years and Older in Texas From 1999-2009

Geography of Hiv Infection Among Adults Aged 50 Years and Older in Texas From 1999-2009

Date: August 2012
Creator: Hedrich, Mara Nicole
Description: Twenty four percent of all HIV infections in the United States occur among adults aged 50 and older (mature adults), yet little is understood of the dynamics of HIV infection among this group in Texas. Data from 1999 to 2009 examined the relationship between HIV spatial and temporal patterns affecting socio-economic and demographic variables including poverty, gender, race/ethnicity and mode of exposure. Results revealed highest HIV infection rates among White homosexual men, Black males engaged in IV-drug use, Black female heterosexuals and minorities in poverty. Concentrations of HIV infection among mature adults were located primarily in urban centers of Houston and Dallas and indicated increasing HIV infection rates from 1999 to 2009. These results will assist future allocation of resources by zip code in urban areas for this understudied population.
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The Geography of Maternal Mortality in Nigeria

The Geography of Maternal Mortality in Nigeria

Date: May 2012
Creator: Ebeniro, Jane
Description: Maternal mortality is the leading cause of death among women in Nigeria, especially women aged between 15 and 19 years. This research examines the geography of maternal mortality in Nigeria and the role of cultural and religious practices, socio-economic inequalities, urbanization, access to pre and postnatal care in explaining the spatial pattern. State-level data on maternal mortality rates and predictor variables are presented. Access to healthcare, place of residence and religion explains over 74 percent of the spatial pattern of maternal mortality in Nigeria, especially in the predominantly Muslim region of northern Nigeria where poverty, early marriage and childbirth are at its highest, making them a more vulnerable population. Targeting vulnerable populations in policy-making procedures may be an important strategy for reducing maternal mortality, which would also be more successful if other socio-economic issues such as poverty, religious and health care issues are promptly addressed as well.
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Geologic and Lithic Analysis of the Red River Cache

Geologic and Lithic Analysis of the Red River Cache

Date: May 2011
Creator: Gregory, Brittney
Description: The Red River Cache is an assemblage of 33 bifaces, found in Cooke County, along Cache Creek, a tributary to the Red River. Also found with the cache was a hearth which yielded charcoal for AMS dating which returned an age of 2770- 2710 Cal YBP placing the cache in the Late Archaic. The geologic investigation of Cache Creek established 3 Holocene allostratigraphic units that provide information depositional environments adjacent to the Red River. Lithic analysis explored the production of bifaces during the Late Archaic and compared the cache to regional records. Using both geologic and lithic analysis this thesis investigates the temporal and cultural context of the cache using a geoarchaeological approach.
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George S Patton Jr and the Lost Cause Legacy

George S Patton Jr and the Lost Cause Legacy

Date: August 2014
Creator: Rodriguez, Ismael
Description: Historians have done their duty in commemorating an individual who was, as Sidney Hook’s Hero in History would describe, an “event making-man.” A myriad of works focused on understanding the martial effort behind George S. Patton Jr. from his ancestral lineage rooted in military tradition to his triumph during the Second World War. What is yet to be understood about Patton, however, is the role that the Civil War played in his transformation into one of America’s iconic generals. For Patton, the Lost Cause legacy, one that idealized the image of the Confederate soldier in terms of personal honor, courage, and duty, became the seed for his preoccupation for glory.
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