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Determination of Bioconcentration Potential of Selected Pharmaceuticals in Fathead Minnow, Pimephales promelas, and Channel Catfish, Ictalurus punctatus

Description: The primary objective of this work was to determine the tissue-specific bioconcentration factors (BCFs) of the selected pharmaceuticals: norethindrone (NET), ibuprofen (IBU), verapamil (VER), clozapine (CLZ) and fenofibrate (FFB) in two freshwater fishes: fathead minnow and channel catfish. BCF tests on fathead followed the standard OECD 42-day test while a 14-day abridged test design was used in catfish exposures. Additional objectives included a) comparing the measured BCFs to the US EPA's BC… more
Date: December 2010
Creator: Nallani, Gopinath C.
Item Type: Refine your search to only Thesis or Dissertation
open access

Developing a Collection Digitization Workflow for the Elm Fork Natural Heritage Museum

Description: Natural history collections house immense amounts of data, but the majority of data is only accessible by locating the collection label, which is usually attached to the physical specimen. This method of data retrieval is time consuming and can be very damaging to fragile specimens. Digitizing the collections is the one way to reduce the time and potential damage related to finding the collection objects. The Elm Fork Natural Heritage Museum is a natural history museum located at the University… more
Date: August 2013
Creator: Evans, Colleen R.
Item Type: Refine your search to only Thesis or Dissertation
open access

Developing a Phylogeny Based Machine Learning Algorithm for Metagenomics

Description: Metagenomics is the study of the totality of the complete genetic elements discovered from a defined environment. Different from traditional microbiology study, which only analyzes a small percent of microbes that could survive in laboratory, metagenomics allows researchers to get entire genetic information from all the samples in the communities. So metagenomics enables understanding of the target environments and the hidden relationships between bacteria and diseases. In order to efficiently … more
Date: August 2017
Creator: Rong, Ruichen
Item Type: Refine your search to only Thesis or Dissertation
open access

The Ecology and Paleobiogeography of Freshwater Mussels (Family: Unionidae) from Selected River Basins in Texas

Description: This dissertation has two overall objectives: first, to demonstrate the utility of paleozoological data for ongoing and future mussel-conservation efforts in Texas and second, to evaluate whether simple measures of habitat (e.g., water depth, velocity and particle size) are important for demonstrating the within-habitat spatial separation of mussels. Although these topics may seem disparate, both are important for increasing our understanding of unionid ecology and biogeography. Chapters 1 th… more
Date: May 2011
Creator: Randklev, Charles R.
Item Type: Refine your search to only Thesis or Dissertation
open access

Ecology and Recolonization of Benthic Macroinvertebrates in a Groundwater-dependent Stream in North Central Texas During a Supra-seasonal Drought

Description: Extreme climatic events such as droughts are known to eliminate aquatic biota and alter community structure and function. Perennial headwater springs provide important drought refugia to benthic macroinvertebrates and an important source of colonists via drift or aerial adults to intermittent streams post-drought. During a supra-seasonal drought in North-central Texas summer and fall 2006, benthic macroinvertebrates from persistent groundwater-dependent macrohabitats of varying hydrological con… more
Date: May 2012
Creator: Burk, Rosemary A.
Item Type: Refine your search to only Thesis or Dissertation
open access

Effect of Acute Alcohol Ingestion on Resistance Exercise Induced mTORC1 Signaling in Human Muscle

Description: The purpose of this project was to further elucidate the effects post-exercise alcohol ingestion. This project had many novel aspects including using a resistance exercise (RE) only exercise design and the inclusion of women. To our knowledge, we are the first to investigate the effect of post-RE alcohol ingestion in women. In the first chapter of this project, information on the prevalence of alcohol use and the importance of skeletal muscle as a dynamic and metabolic tissue was provided. In c… more
Date: August 2015
Creator: Duplanty, Anthony A.
Item Type: Refine your search to only Thesis or Dissertation
open access

The Effect of Curcumin Supplementation on Physical and Biological Indices of Delayed Onset Muscle Soreness and Inflammation Following Muscle Injury

Description: In this project, the effects of dietary polyphenols on exercise-induced muscle damage and vascular health are examined. Dietary polyphenols exert well-known anti-inflammatory effects; however, how these effects are realized with respect to vascular health and EIMD is relatively unknown. I begin by reviewing the available literature surrounding the impact of three dietary polyphenols (curcumin, catechins, and quercetin) on inflammation associated with EIMD. It is well established that their prim… more
Date: May 2015
Creator: Venable, Adam Steven
Item Type: Refine your search to only Thesis or Dissertation
open access

The Effect of Menthol on Nicotine Metabolism: a Cross Species Evaluation

Description: The effect of menthol on nicotine metabolism was examined in liver S9 fractions of four different species and in the in vivo mouse model. The purpose of this study was to investigate three parameters: (1) biotransformation of nicotine to cotinine in various species (human, mouse, rat and trout) using in vitro methods; (2) to determine if the addition of menthol with nicotine altered biotransformation of nicotine to cotinine; (3) and to assess similar parameters in an in vivo mouse model. The… more
Date: December 2013
Creator: Pace, Wendy Lee
Item Type: Refine your search to only Thesis or Dissertation
open access

The Effect of Post-exercise Ethanol Consumption on the Acute Hormonal Response to Heavy Resistance Exercise in Women

Description: The purpose of this study was to examine the hormonal response to acute ethanol ingestion following a bout of heavy resistance exercise in women. Eight resistance trained women completed two identical acute heavy resistance exercise tasks (AHRET). From 10-20 minutes post-AHRET, participants consumed either a grain ethanol or a placebo beverage. Blood was collected before (PRE) and immediately after the AHRET (IP) and then every 20 minutes for five hours. Blood collected after beverage ingestion… more
Date: December 2015
Creator: Budnar, Ronald Gene, Jr.
Item Type: Refine your search to only Thesis or Dissertation
open access

Effect of the Resistance Exercise-Induced Hormonal Changes on Satellite Cell Myogenic State

Description: Skeletal muscle satellite cells are important for muscle repairing and muscle mass growth. For a successful muscle regenerative process, satellite cells have to sequentially undergoing different stages of myogenic process, i.e. proliferative state and differentiation state. To support this process, the presence of different circulating factors, such as immune cells, cytokines, and hormones, at the appropriate time course is critical. Among these factors, hormones, such as testosterone, cortisol… more
Date: May 2018
Creator: Luk, Hui Ying
Item Type: Refine your search to only Thesis or Dissertation
open access

Effects of Airway Pressure, Hypercapnia, and Hypoxia on Pulmonary Vagal Afferents in the Alligator (Alligator Misssissippiensis)

Description: The American alligator (Alligator mississippiensis) is an aquatic diving reptile with a periodic breathing pattern. Previous work has identified pulmonary stretch receptors (PSR), both rapidly- and slowly-adapting, and intrapulmonary chemoreceptors (IPCs) that modulate breathing patterns in alligators. The purpose of the present study was to identify the effects of prolonged lung inflation and deflation (simulated dives) on PSR and/or IPC firing characteristics in the alligator. The effects of … more
Date: December 2013
Creator: Marschand, Rachel E.
Item Type: Refine your search to only Thesis or Dissertation
open access

Effects of Brain Injury on Primary Cilia of Glial Cells and Pericytes

Description: Glial cells maintain homeostasis that is essential to neuronal function. Injury to the nervous system leads to the activation and proliferation of glial cells and pericytes, which helps to wall off the damaged region and restore homeostatic conditions. Sonic hedgehog is a mitogen which is implicated in injury-induced proliferation of glial cells and pericytes. The mitogenic effects of sonic hedgehog require primary cilia, but the few reports on glial or pericyte primary cilia do not agree about… more
Date: December 2016
Creator: Coronel, Marco V.
Item Type: Refine your search to only Thesis or Dissertation
open access

Effects of CFT Legumine™ Rotenone on Macroinvertebrates in Four Drainages of Montana and New Mexico

Description: Rotenone is considered essential in the restoration of native fish populations; however, the technique is contentious and criticized, specifically concerning impacts to invertebrates. Knowledge of effects to non-target organisms is important for the management and conservation of fish populations. This thesis has two general objectives: (1) demonstrate the influence CFT Legumine™ rotenone has on benthic macroinvertebrates for restoration projects in Montana and New Mexico and (2) evaluate the i… more
Date: August 2011
Creator: Skorupski, Joseph A., Jr.
Item Type: Refine your search to only Thesis or Dissertation
open access

Effects of Deepwater Horizon Crude Oil on Visual Function in Teleost Fishes

Description: The Deepwater Horizon oil spill released millions of barrels of oil into the Gulf of Mexico, impacting economically and ecologically important fishes. Polycyclic aromatic hydrocarbons (PAHs) present in the oil have been shown to cause developmental impairments in early life stage fishes, such as morphological and behavioral changes related to eye formation and visual processing following PAH exposure. Prior research reported reduced eye growth in open water, pelagic species, as well as reduce… more
Date: August 2018
Creator: Magnuson, Jason T
Item Type: Refine your search to only Thesis or Dissertation
open access

The Effects of Inbreeding on Fitness Traits in the Critically Endangered Attwater’s Prairie-chicken

Description: The goals of captive breeding programs for endangered species include preserving genetic diversity and avoiding inbreeding. Typically this is accomplished by minimizing population mean kinship; however, this approach becomes less effective when errors in the pedigree exist and may result in inbreeding depression, or reduced survival. Here, both pedigree- and DNA-based methods were used to assess inbreeding depression in the critically endangered Attwater’s prairie-chicken (Tympanuchus cupido … more
Date: August 2014
Creator: Hammerly, Susan C.
Item Type: Refine your search to only Thesis or Dissertation
open access

Effects of Peripheral Nerve Injury on the Cells of the Dorsal Root Ganglion: a Role for Primary Cilia

Description: Primary cilia are ubiquitous sensory organelles found on most cell types including cells of the dorsal root ganglia (DRG). The DRG are groups of peripheral neurons that relay sensory information from the periphery to the CNS. Other cell types in the DRG include a type of glial cell, the satellite glial cells (SGCs). The SGCs surround the DRG neurons and, with the neurons, form functional sensory units. Currently are no reports describing the numbers of DRG cells that have cilia. We found tha… more
Date: December 2012
Creator: Smith, Sarah K.
Item Type: Refine your search to only Thesis or Dissertation
open access

Endocannabinoid System in a Planarian Model

Description: In this study, the presence and possible function of endocannabinoid ligands in the planarian is investigated. The endocannabinoids ananadamide (AEA) and 2-arachidonoylglycerol (2-AG) and entourage NAE compounds palmitoylethanolamide (PEA), stearoylethanolamide (SEA) and oleoylethanolamide (OEA) were found in Dugesia dorotocephala. Changes in SEA, PEA, and AEA levels were observed over the initial twelve hours of active regeneration. Exogenously applied AEA, 2-AG and their catabolic inhibition … more
Date: December 2010
Creator: Mustonen, Katie Lynn
Item Type: Refine your search to only Thesis or Dissertation
open access

Endocrine Disruption of Levonorgestrel in Early-life Stages of Fathead Minnows, Pimephales Promelas

Description: Pharmaceuticals have routinely been detected in the environment resulting in a growing concern about whether these drugs could elicit effects on aquatic organisms. The concerns are centered on the highly conserved nature of mammalian therapeutic targets in fish. These pharmaceuticals are found at very low levels in the environment, which can result in sub-lethal effects in aquatic organisms. Therefore, 28 d early-life stage studies were conducted on six pharmaceuticals to assess their impact… more
Date: August 2013
Creator: Overturf, Matthew D.
Item Type: Refine your search to only Thesis or Dissertation
open access

Environmental Modulation of the Onset of Air-breathing of the Siamese Fighting Fish and the Blue Gourami

Description: This study determined the effect of hypoxia on air-breathing onset and physiological and morphological characters in larvae of the air breathing fishes Trichopodus trichopterus and Betta splendens. Larvae were exposed intermittently (12/12 h daily) to 20, 17, and 14 kPa of PO2 from 1 to 40 days post-fertilization. Survival, onset of air breathing, wet body mass, O2, Pcrit were measured every 5 dpf. Hypoxia advanced by 4 days, and delayed by 9 days, the onset of air breathing in Betta and Trich… more
Date: December 2015
Creator: Mendez Sanchez, Jose Fernando
Item Type: Refine your search to only Thesis or Dissertation
open access

Estimating Postmortem Interval Using VNIR Spectroscopy on Human Cortical Bone

Description: Postmortem interval (PMI) estimation is a necessary but often difficult task that must completed during a death investigation. The level of difficulty rises as time since death increases, especially with the case of skeletonized remains (long PMI). While challenging, a reliable PMI estimate may be of great importance for investigative direction and cost-savings (e.g. suspect identification, tailoring missing persons searches, non-forensic remains exclusion). Long PMI can be estimated by assessi… more
Date: May 2018
Creator: Servello, John A.
Item Type: Refine your search to only Thesis or Dissertation
open access

Evaluating the Habitat Requirements of the Golden Orb Mussel (Quadrula Aurea) for Conservation Purposes

Description: Many freshwater mussels are imperiled, due to a number of interrelated factors such as habitat alteration, degradation of water quality, and impoundments. The Golden Orb mussel (Quadrula aurea, I. Lea, 1859) is endemic to the state of Texas and is currently a candidate for the endangered species list, as the number of known populations has been declining in recent years. Little is currently known about Q. aurea aside from basic distribution data. This study is focused on evaluating a combinatio… more
Date: May 2013
Creator: Hammontree, Sarah
Item Type: Refine your search to only Thesis or Dissertation
open access

Evaluating the Role of UV Exposure and Recovery Regimes in PAH Photo-Induced Toxicity to Daphina Magna

Description: Polyaromatic hydrocarbons (PAHs) are contaminants synthesized through incomplete combustion of carbon based substances. PAHs are known to be photodynamic and toxicity increases exponentially when in contact with ultraviolet radiation (UV). The effect of UV absent recovery periods and potential for latent toxicity during photo-induced toxicity are previously unknown and are not included within the toxicity model. Results of equal interval tests further support the current reciprocity model as a … more
Date: August 2017
Creator: Gnau, Jennifer Leigh
Item Type: Refine your search to only Thesis or Dissertation
open access

Examination of the Relationship Between Glucuronic Acid and Vascular Damage in Rats

Description: The goal of this experiment was to examine the role of glucuronic acid in the development of vascular damage in the kidneys and retinas of diabetic individuals. Glucuronic acid was provided to rats in their water at various concentrations in order to increase plasma levels of the compound. Kidneys and retinas were excised and compared to control specimens using microscopy to determine the effect of elevated blood glucuronic acid levels on the occurrence of microaneurysms in renal capillary netw… more
Date: May 2013
Creator: Moore, Ryan
Item Type: Refine your search to only Thesis or Dissertation
open access

Exploring the Evolutionary History of North American Prairie Grouse (Genus: Tympanuchus) Using Multi-locus Coalescent Analyses

Description: Conservation biologists are increasingly using phylogenetics as a tool to understand evolutionary relationships and taxonomic classification. The taxonomy of North American prairie grouse (sharp-tailed grouse, T. phasianellus; lesser prairie-chicken, T. pallidicinctus; greater prairie-chicken, T. cupido; including multiple subspecies) has been designated based on physical characteristics, geography, and behavior. However, previous studies have been inconclusive in determining the evolutionary h… more
Date: May 2013
Creator: Galla, Stephanie J.
Item Type: Refine your search to only Thesis or Dissertation
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