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  Access Rights: Use restricted to UNT Community
  Partner: UNT Libraries
 Decade: 2000-2009
 Year: 2001
 Collection: UNT Theses and Dissertations
4-Ethoxymethylphenol: a novel phytoestrogen that acts as an agonist for human estrogen receptors.

4-Ethoxymethylphenol: a novel phytoestrogen that acts as an agonist for human estrogen receptors.

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Date: December 2001
Creator: Pearce, Virginia
Description: Estrogen is the natural agonist of the estrogen receptor (ER). However, certain plant-derived compounds or phytoestrogens have been identified that mimic estrogens and act as agonists and/or antagonists of ERs, depending on subtype and target tissue. Understanding how phytoestrogens interact with ERs, and therefore effect the estrogenic response, may prove beneficial in hormone replacement therapy and in the prevention and treatment of hormone-related diseases. Using Thin Layer Chromatography, gas chromatography/mass spectrometry (GC/MS), and proton nuclear nagnetic resonance (HNMR), I identified 4-ethoxymethylphenol (4EM) found in Maclura pomifera. While most phytoestrogens are heterocyclic compounds, 4EM is a simple phenol that acts as an agonist of ER-alpha and -beta in HeLa and MCF-7 cells. To study the effect of 4EM on ER-alpha and -beta activity, I performed transient transfection assays and showed that 4EM activates ER dependent gene transcription in a dose dependent manner in both ER subtypes. Further, 4EM- mediated transcription in ER-alpha, like estrogen, was enhance in the presense of co-activators, SRC-1 (steroid receptor coactivator-1), CBP (CREB binding proteins), and E6-AP (E6-associated protein) and inhibited by trans-4- hydroxytamoxifen (4HT). I found that 4EM was specific for ER and did not activate transcription of the progesterone receptor in HeLa cells.
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Alexander Johnson's Ni' Concerto (1994) - Concerto no. 1 for Piano and Orchestra: a Discussion of Influences from Africa, Eastern and Western Europe

Alexander Johnson's Ni' Concerto (1994) - Concerto no. 1 for Piano and Orchestra: a Discussion of Influences from Africa, Eastern and Western Europe

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Date: August 2001
Creator: Malan, Petronel
Description: In the new generation of artists emerging in South Africa, Alexander Johnson is considered the most prolific young composer of his day. In a recent review in the Pretoria News, Johnson has been praised by eminent critic Paul Boekkooi as a composer who has “an ear for the exotic and knows exactly how to bring it off....” He continued by noting that his music is “mentally engrossing, pleasurable to the senses and seems refreshingly free from dogmatic formulas." Johnson writes for musicians and the general public to equal satisfaction. His accessible compositions and catching use of melodic materials have made his writings very popular both in South Africa and abroad. During his residency in Belgrade in 1993-94, Johnson met Croatian pianist Dorian Leljak. Impressed with Johnson's compositional ideas and output, Leljak commissioned a work from Johnson for piano and orchestra. The result was the Niš Concerto, which Johnson completed in April 1994. The world premiere took place on June 23, 1994 with the Niš Philharmonic Orchestra conducted by Anatoli Nowiestski with Dorian Leljak as soloist. The Niš Concerto received its South African premiere in 1995 during a simultaneous celebration for “Europe Day” and the new democracy of the Republic of ...
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An Analysis of Major American Riots: Issues in Riots and Riot Control

An Analysis of Major American Riots: Issues in Riots and Riot Control

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Date: August 2001
Creator: Cinoglu, Huseyin
Description: By conducting sound research to understand the concepts surrounding rioting and efficient riot response tactics, professionals, especially whose main job is to ensure the tranquility in the society, will be better prepared to deal with all kinds of civil movements. The purpose of this study, consequently, is to meet the growing need for educational materials in this area and to provide riot response case studies, which demonstrate the numerous administrative challenges faced by law enforcement decision makers. In this study, seven major riots from throughout the United States are discussed including the Hay Market Riot of 1886, the Watts Riot of 1965, and Los Angeles Riots of 1992. Each riot case is studied in five different and independent stages: the setting and pre-disturbance situation, basic causes of the event, the disturbance situation, the response to the riot, and the aftermath of the incident. The study of all of these stages is intended to help police administrators acquire a general perspective on collective violence, and help them prevent future occurrences in their jurisdictions. In this thesis a special reference is given to the deficiencies of American riot policing and some recommendations were formed accordingly. Therefore, the study concludes with a list ...
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Analysis of the Impact of CACREP Accreditation of Counselor Education Programs on Student Knowledge Outcomes

Analysis of the Impact of CACREP Accreditation of Counselor Education Programs on Student Knowledge Outcomes

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Date: May 2001
Creator: Scott, Susan W.
Description: The principal investigator (PI) for this study analyzed mean scores on the National Counselor Examination (NCE) of students from CACREP accredited and non- CACREP accredited programs. Data was provided by the National Board of Certified Counselors, Inc., for a total of ten examination administrations across six years. The fourteen variables examined in the study consisted of the eight common-core knowledge domains identified in CACREP standards, the five counselor work behavior areas identified by NBCC via periodic job analysis of counseling practice, and one overall or total score on the NCE. NCE mean scores of students from CACREP accredited programs were higher than NCE mean scores of students from non-CACREP accredited programs on all variables across all ten NCE administrations. Data seem to indicate that students from CACREP accredited programs perform significantly better on the NCE than students from non-CACREP accredited programs, in all fourteen variables. Sample size was large, totaling 9707, so the PI calculated effect sizes using Cohen's d for each variable to aid interpretation of statistical significance. Five variables had large effect sizes of .70 or higher. The higher effect size statistics were associated with the counselor work behavior areas, with the highest effect size (.85) associated with ...
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Animal contribution to human medicine

Animal contribution to human medicine

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Date: May 2001
Creator: Kvernes, Kayce
Description: The use of animal models in research has led to a fierce debate between animal rights activists and scientists. The former claim that little useful information is gained from animal studies and the suffering of animals does not preclude any treatments which may be used to treat human illnesses. Yet, research scientists claim that in vivo animal models are of absolute necessity to developing treatments and cures to disease. To determine the necessity of animal use, one must examine the models currently in research. Have the animal models for disorders such as cystic fibrosis and muscular dystrophy given scientists enough information to develop effective treatments? This paper will examine the role of animal subjects in several disease research protocols, as well as the applicability of the research.
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Anne Brontë's New Women:  Agnes Grey and  The Tenant of Wildfell Hall as Precursors of New Woman Fiction

Anne Brontë's New Women: Agnes Grey and The Tenant of Wildfell Hall as Precursors of New Woman Fiction

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Date: August 2001
Creator: Phillips, Jennifer K.
Description: Anne Brontë's Agnes Grey and The Tenant of Wildfell Hall were published more than forty years before the appearance of the feminist type that the Victorians called the “New Woman;” yet, both novels contain characteristics of New Woman fiction. By considering how Brontë's novels foreshadow New Woman fiction, the reader of these novels can re-enact the “gentlest” Brontë as an influential feminist whose ideology informed the construction of the radical New Woman. Brontë, like the New Woman writers, incorporated autobiographical dilemmas into her fiction. By using her own experiences as a governess, Brontë constructs Agnes Grey's incongruent social status and a morally corrupt gentry and aristocracy through her depiction of not only Agnes's second employers, the Murrays, but also the morally debauched world that Helen enters upon her marriage to Arthur Huntingdon in The Tenant of Wildfell Hall. Moreover, Brontë incorporates her observations of Branwell's alcoholism and her own religious beliefs into The Tenant of Wildfell Hall. Although Brontë's novels contain autobiographical material, her heroines are fictional constructions that she uses to engage her readers with the woman question. Brontë accomplishes this engagement through her heroines' narrative re-enactments of fictional autobiographical dilemmas. Helen's diary and Agnes's diary-based narrative produce the ...
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Barriers Limiting Access to Hospice Care for Elderly African Americans in Amarillo, Texas

Barriers Limiting Access to Hospice Care for Elderly African Americans in Amarillo, Texas

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Date: August 2001
Creator: Anthony, Tomagene
Description: This study examines barriers limiting access to hospice care for elderly African Americans. Ethnic background plays a critical role in the development of attitudes, beliefs and expectations related to death and issues surrounding hospice care. The purpose of this study was to identify barriers that may limit access to hospice care for African Americans. A questionnaire was administered to 56 elderly African Americans in three religious settings and an African American senior citizens center. The questionnaire was designed to obtain information concerning African Americans' attitudes toward death and dying; religious beliefs; health beliefs; familiarity with hospice and prospective use of hospice. The results of the study indicate a number of barriers in access to hospice care for African Americans including: hospice knowledge barriers; education/outreach barriers; cultural knowledge barriers related to death/dying values; family/social support barriers; hospice organizational/provider barriers; health care organizational/provider barriers; and reimbursement barriers.
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The Break-up of the Confederate Trans-Mississippi Army, 1865

The Break-up of the Confederate Trans-Mississippi Army, 1865

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Date: May 2001
Creator: Clampitt, Brad R.
Description: Unlike other Confederate armies at the conclusion of the Civil War, General Edmund Kirby Smith's Trans-Mississippi Army disbanded, often without orders, rather than surrender formally. Despite entreaties from military and civilian leaders to fight on, for Confederate soldiers west of the Mississippi River, the surrender of armies led by Generals Robert E. Lee and Joseph E. Johnston ended the war. After a significant decline in morale and discipline throughout the spring of 1865, soldiers of the Confederate Trans-Mississippi Department chose to break-up and return home. As compensation for months of unpaid service, soldiers seized both public and private property. Civilians joined the soldiers to create disorder that swept many Texas communities until the arrival of Federal troops in late June.
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Burnout Among Student Affairs Professionals at Metropolitan Universities

Burnout Among Student Affairs Professionals at Metropolitan Universities

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Date: August 2001
Creator: Murphy, Lynda
Description: The purpose of this study was to determine the level of burnout among student affairs professionals at the 52 U.S. member institutions of the Coalition of Urban and Metropolitan Universities. Packets containing the Maslach Burnout Inventory (MBI), the Moos Work Environment Scale (WES), and a demographic survey were mailed to 371 senior student affairs administrators at the member institutions, with a completed response rate of 58.22%. The senior student affairs administrators surveyed included the chief student affairs officers and the professional staff who reported to them. The research design employed t-tests, analyses of variance, and Pearson's Product Moment correlations. The scores obtained from the MBI and WES subscales were compared overall and along 9 independent variablestitle of position, size of institution, appointment, salary, years in current position, years in profession, age, gender, and highest degree attained. Average levels of burnout were found on each of the MBI subscores. Contrary to earlier studies, women did not suffer from statistically significant higher levels of burnout than men, and burnout levels decreased with age and years in the profession for both sexes. Lower scores on the MBI depersonalization subscale were found in employees in mid-career and in professionals from smaller schools. Emotional exhaustion ...
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A Case Study of Leftist Terrorism in Turkey: DHKP/C

A Case Study of Leftist Terrorism in Turkey: DHKP/C

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Date: August 2001
Creator: Yayla, Ahmet
Description: Change in government has characterized the development of most nations. Sometimes this change has been marked by continued evolution, in a peaceful attempt to move forward. Other times, change has been fraught with violent revolution and terrorism. This process has been the subject of much debate by political scientists and economic philosophers. Today, Turkey suffers from continued threats to its government through violent acts of terrorism conducted by various groups, expressing ideologies of leftist and rightist organizations, as well as ethnic and religious extremists. This thesis examines DHKP/C as the primary leftist revolutionary group effecting Turkey, exploring its historical background in Europe and the Middle East, as well as its philosophical link to Marxism. Further, this treatise discusses the implication of revolution and terrorism expressed by DHKP/C; and explores innovative and peaceful solutions, strategies, and techniques to be used by the police forces of Turkey in combating this group
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