Substituent Effects on Diazeniumdiolate Anions: an AB Initio and DFT Study
Description:
Nitroglycerin and isoamyl nitrate have been used as nitrovasodilators since the nineteeth century. However, not until recently has it been known that these compounds were useful since they promoted the release of NO in the body. More recently, a new class of drugs, NO donors, has been developed. These include S-nitrosothiols (RSNO), sydnonimines, and nucleophilic NO adducts.
Date:
December 1997
Creator:
García, Samuel A. (Samuel Anthony)