Search Results

1-Benzyl-3,5-bis(4-chlorobenzylidene)-piperidin-4-one
The title compound, C₂₆H₂₁Cl₂NO, crystallizes with two symmetry-independent molecules in the asymmetric unit.
3,5-Bis(4-chlorobenzylidene)-1-methyl-piperidin-4-one
In the title molecule, C₂₀H₁₇Cl₂NO, the central heterocyclic ring adopts a flattened boat conformation.
4-Coumarate 3-hydroxylase in the lignin biosynthesis pathway is a cytosolic ascorbate peroxidase
Article describes an enzyme catalyzing the direct 3-hydroxylation of 4-coumarate to caffeate in lignin biosynthesis as a bifunctional peroxidase that oxidizes both ascorbate and 4-coumarate at comparable rates.
ABA Is Required for Plant Acclimation to a Combination of Salt and Heat Stress
This article highlights the important role abscisic acid plays in the acclimation of plants to a combination of two different abiotic stresses.
ABA is required for the accumulation of APX1 and MBF1c during a combination of water deficit and heat stress
This article studies the response of mutants impaired in ABA signalling (abi1-1) and biosynthesis (aba1-1) to a combination of water deficit and heat stress.
Abscisic acid regulates secondary cell-wall formation and lignin deposition in Arabidopsis thaliana through phosphorylation of NST1
Article using a combination of biochemical and genetic approaches to show how ABA can regulate lignin biosynthesis. This work provides a basis for designing trees and other biomass plants that are better adapted to stress and climate change. This article includes a correction on the first page.
The accessory role of the diaphragmaticus muscle in lung ventilation in the estuarine crocodile Crocodylus porosus
This article explores lung ventilation in crocodilians through direct measurements of ventilation, metabolic rate, and arterial blood gases of juvenile estuarine crocodiles in varying conditions. The results suggest that, in C. porosus, costal ventilation alone is able to support metabolic demands at rest, and the diaphragmaticus is largely an accessory muscle used at times of elevated metabolic demand.
Accumulation of Flavonols over Hydroxycinnamic Acids Favors Oxidative Damage Protetion under Abiotic Stress
This article reports on the characterization of the different antioxidant mechanisms of tomato plants subjected to heat stress, salinity stress, or a combination of both stresses.
Accumulation of α-Keto Acids as Essential Components in Cyanide Assimilation by Pseudomonas fluorescens NCIMB 11764
Article on the accumulation of α-Keto acids as essential components in cyanide assimilation by Pseudomonas fluorescens NCIMB 11764.
Acid-base regulation in the air-breathing swamp eel (Monopterus albus) at different temperatures
Article describes study in which researchers characterized the influence of temperature on arterial acid–base balance and intracellular pH (pHi) in the bimodal-breathing swamp eel, Monopterus albus.
Activation of an S6/H4 Kinase (PAK 65) from Human Placenta by Intramolecular and Intermolecular Autophosphorylation
Article proposing a model in which phosphorylation of sites 1 and 2 occurs sequentially. The model proposes that trypsin treatment of the inactive holoenzyme removes an inhibitory rac-binding domain which blocks MgATP access to the catalytic site. The pseudosubstrate domain at site 1 is autophosphorylated and subsequent bimolecular autophosphorylation at site 2 fully opens the catalytic site.
Activation of an S6 Kinase From Human Placenta by Autophosphorylation
Article describing a novel S6 kinase isolated from human placenta which autoactivates through autophosphorylation in vitro. The data supports the hypothesis that this previously uncharacterized S6 kinase belongs to a unique family of protein kinases which utilize autophosphorylation as part of their in vivo activation mechanism.
Activation of apoptosis in NAF-1-deficient human epithelial breast cancer cells
This article shows that small hairpin RNA-mediated suppresion of NAF-1 results in the activation of apoptosis in epithelial breast cancer cells and xenograft tumors.
N-acylethanolamide metabolizing enzymes are upregulated in human neural progenitor-derived neurons exposed to sub-lethal oxidative stress
Article is a study determining whether ReN cells, a superior cell model system for studying neurodevelopment, differentiation, and neuroprotection, express proteins involved in canonical eCB NAE signaling and whether oxidative stress can induce their expression. This study is a first step toward determining how oxidative stress affects CB1, CB2, FAAH, NAAA, and NAPE-PLD expression and their potential defense against oxidative stress.
N-Acylethanolamine Metabolism Interacts with Abscisic Acid Signaling in Arabidopsis thaliana Seedlings
Article discussing N-acylethanolamine metabolism interacting with abscisic acid signaling in Arabidopsis thaliana seedlings.
N-Acylethanolamine Signaling in Tobacco is Mediated by a Membrane-Associated, High-Affinity Binding Protein
Article on N-acylethanolamine signaling in tobacco and how it is mediated by a membrane-associated, high-affinity binding protein.
N-Acylethanolamine Signaling in Tobacco is Mediated by a Membrane-Associated, High-Affinity Binding Protein
Article on N-acylethanolamine signaling in tobacco is mediated by a membrane-associated, high-affinity binding protein.
N-Acylethanolamines are Metabolized by Lipoxygenase and Amidohydrolase in Competing Pathways during Cottonseed Imbibition
Article on N-acylethanolamines metabolizing by lipoxygenase and amidohydrolase in competing pathways during cottonseed inbibition.
N-Acylethanolamines: Formation and Molecular Composition of a New Class of Plant Lipids
Article on N-acylethanolamines and the formation and molecular composition of a new class of plant lipids.
N-Acylethanolamines in Seeds. Quantification of Molecular Species and their Degradation upon Imbibition
Article on N-acylethanolamines in seeds and the quantification of molecular species and their degradation upon imbibition.
N-Acylethanolamines in Signal Transduction of Elicitor Perception. Attenuation of Alkalinization Response and Activation of Defense Gene Expression
Article on N-acylethanolamines in signal transduction of elicitor perception and the attenuation of alkalinization response and activation of defense gene expression.
N-Acylphosphatidylethanolamine in Dry and Imbibing Cottonseeds. Amounts, Molecular Species, and Enzymatic Synthesis
Article on N-acylphosphatidylethanolamine in dry and imbibing cottonseeds.
The AGC Kinase MtIRE: A Link to Phospholipid Signaling During Nodulation?
Article discussing the AGC Kinase gene MtIRE and the possibility of a link to phospholipid signaling during nodulation.
Agronomic Performance and Lignin Content of HCT Down-Regulated Alfalfa (Medicago sativa L.)
This article evaluates HCT down-regulated alfalfa plants for their forage composition and agronomic performance in the greenhouse and under field conditions.
Air pollution and endocrine disruptors induce human microbiome imbalances: A systematic review of recent evidence and possible biological mechanisms
Article presents a systematic review examining the scientific evidence on the effect of environmental toxicants, air pollutants and endocrine disruptors (EDCs), on compositional and diversity of human microbiota.
Allelic differences in Medicago truncatula NIP/LATD mutants correlate with their encoded proteins’ transport activities in planta
This article examines the hypothesis that MtNIP/LATD may have another biochemical activity.
Altered brain ion gradients following compensation for elevated CO2 are linked to behavioural alterations in a coral reef fish
This article pairs a behavioural assay with measurements of relevant intracellular and extracellular acid-base parameters in a coral reef fish exposed to elevated CO₂.
Altered embryonic development in northern bobwhite quail (Colinus virginianus) induced by pre-incubation oscillatory thermal stresses mimicking global warming predictions
This article describes the exposure of freshly laid bobwhite quail eggs to one of five thermal regimes during a 12 day pre-incubation period.
Altered expression of ionotropic L-Glutamate receptors in aged sensory neurons of Aplysia californica
Article describes study in which mRNA expression of iGluR was quantified in two sensory neuron clusters of two cohorts of Aplysia californica (Aplysia) at both sexual maturity (~8 months) and advanced age (~12 months) in order to examine if changes in ionotropic L-Glu receptor (iGluR) transcription underlie reduced physiology8
Altitudinal gradients in Magellanic sub-Antarctic lagoons: the effect of elevation on freshwater macroinvertebrate diversity and distribution
In this article, freshwater macroinvertebrate diversity associated with lakes and ponds along the altitudinal gradient of a Magellanic sub-Antarctic watershed are assessed. A monotonic decline in species richness was observed with increasing elevation, with simpler and more even community composition at higher altitude. This pattern differs from the mid-peak trend found in streams of the same watershed. Functional feeding group structure also diminished with increasing elevation.
Analysis of cDNA libraries from developing seeds of guar (Cyamopsis tetragonoloba (L.) Taub)
Article on the analysis of cDNA libraries from developing seeds of guar (Cyamopsis tetragonoloba (L.) Taub).
Analysis of Pectin-derived Monosaccharides from Arabidopsis Using GC–MS
Article describes how pectin is a complex polysaccharide present in the plant cell wall, whose composition is constantly remodeled to adapt to environmental or developmental changes. Here, authors describe a quick and efficient gas chromatography–mass spectrometry (GC–MS)-based method that allows the differential analysis of pectin monosaccharide composition in plants under different conditions or between mutant plants and their respective wild types.
Analysis of the Genome of a Korean Isolate of the Pieris rapae Granulovirus Enabled by Its Separation from Total Host Genomic DNA by Pulse-Field Electrophoresis
Article on an analysis of the genome of a Korean isolate of the Pieris rapae granulovirus enabled by its separation from total host genomic DNA by pulse-field electrophoresis.
An Analysis of the Habitat of the Greater One-Horned Rhinoceros Rhinoceros Unicornis (Mammalia: Perissodactyla: Rhinocerotidae) at the Chitwan National Park, Nepal
This article uses geographic information systems and landscape-level data obtained from remote sensing sources to build a habitat suitability index model for the Greater One-horned Rhinoceros.
Analysis of the potential behavioral impact of methanol when used as a solvent: Dataset from zebrafish (Danio rerio) behavioral research
This article is a dataset that describes behavioral results in zebrafish (Danio rerio) individually exposed to methanol, a solvent which is capable of altering physiology and behavior high concentrations.
Analysis of transcribed sequences from young and mature zebrafish thrombocytes
Article studying thrombocyte function and development in adult zebrafish. The authors performed single-cell RNA sequencing of the young and mature zebrafish thrombocytes and compared the two datasets for young and mature thrombocyte transcripts.
Analyzing Mass Spectrometry Imaging Data of 13C-Labeled Phospholipids in Camelina sativa and Thlaspi arvense (Pennycress) Embryos
This article uses currently available software and techniques to describe a workflow to analyze ¹³C-labeled isotopologues of the membrane lipid and storage oil lipid intermediate—phosphatidylcholine (PC). Results demonstrated greater ¹³C-isotopic labeling in the cotyledons of developing embryos compared with the embryonic axis.
Angiogenesis in the Avian Embryo Chorioallantoic Membrane: A Perspective on Research Trends and a Case Study on Toxicant Vascular Effects
This article considers areas of cardiovascular research that have benefited from studies of the chorioallantoic membrane (CAM), including the themes of investigation of the CAM’s hemodynamic influence on heart and central vessel development, use of the CAM as a model vascular bed for studying angiogenesis, and the CAM as an assay tool.
Anthocyanidin reductases from Medicago truncatula and Arabidopsis thaliana
Article on anthocyanidin reductases from Medicago truncatula and Arabidopsis thaliana.
An anthraquinone derivative, emodin sensitizes hepatocellular carcinoma cells to TRAIL indced apoptosis through the induction of death receptors and downregulation of cell survival proteins
Article on an anthraquinone derivative, emodin sensitizes hepatocellular carcinoma cells to TRAIL induced apoptosis through the induction of death receptors and downregulation of cell survival proteins.
Antiviral Activity of Metal-Containing Polymers—Organotin and Cisplatin-Like Polymers
This article examines the use of metal-containing polymers as a novel class of antivirals. Polymers containing platinum and to a lesser extent tin, have repeatedly demonstrated antitumor activity in vitro and in vivo against a variety of cell and tumor types. The mechanisms responsible for the antitumor activity include inducing a delay in cell proliferation and sister chromatid exchanges blocking tumor growth.
ANXA1 inhibits miRNA-196a in a negative feedback loop through NF-kB and c-Myc to reduce breast cancer proliferation
This article shows that miR196a was highly expressed in ER+MCF-7 breast cancer cells when compared to normal mammary gland cells, with expression levels negatively correlating to ANXA1.
Application of Genome Editing in Tomato Breeding: Mechanisms, Advances, and Prospects
This article is a review presenting examples of gene editing responsible for conferring both biotic and abiotic stresses in tomato simultaneously. The literature on using this powerful technology to improve fruit quality, yield, and nutritional aspects in tomato is highlighted.
Applications of Fourier Transform Ion Cyclotron Resonance (FT-ICR) and Orbitrap Based High Resolution Mass Spectrometry in Metabolomics and Lipidomics
This review explores the latest developments in Fourier transform mass spectrometry and Orbitrap based metabolomics technology, its advantages and drawbacks for using in metabolomics and lipidomics studies, and development of novel approaches for processing high resolution mass spectrometry data.
ARABIDOPSIS DEHISCENCE ZONE POLYGALACTURONASE 1 (ADPG1) releases latent defense signals in stems with reduced lignin content
Article highlights the importance of pectin in cell wall integrity and the value of lignin modification as a tool to interrogate the informational content of plant cell walls.
The Arabidopsis gene co-expression network
Article presents an Arabidopsis gene co-expression network constructed using RNA-Seq datasets, which will serve as a useful resource for the Arabidopsis research community to gain insights into Arabidopsis gene interactions and functions.
An Arabidopsis Oxalyl-CoA Decarboxylase, AtOXC, Is Important for Oxalate Catabolism in Plants
This article identifies, in Arabidopsis, an oxalyl-CoA decarboxylase (AtOXC) that is capable of catalyzing the second step in the proposed pathway of oxalate catabolism.
The Arabidopsis PAD4 Lipase-Like Domain Is Sufficient for Resistance to Green Peach Aphid
Article exploring PAD4 functions in plant defense by expressing the N-terminal PAD4 lipase-like domain (PAD4ᴸᴸᴰ) without its C-terminal EDS1-PAD4 (EP) domain. The authors show that transgenic expression of PAD4ᴸᴸᴰ in Arabidopsis is sufficient for limiting GPA infestation but not for conferring basal and effector-triggered pathogen immunity. This suggests that the C-terminal PAD4 EP domain is necessary for EDS1-dependent immune functions but is dispensable for aphid resistance. Moreover, PAD4ᴸᴸᴰ is not sufficient to interact with EDS1, indicating the PAD4-EP domain is required for stable heterodimerization. These data provide molecular evidence that PAD4 has domain-specific functions.
Arabidopsis thaliana EARLY RESPONSIVE TO DEHYDRATION 7 Localizes to Lipid Droplets via Its Senescence Domain
This article includes a proteomics analysis of Lipid Droplets (LDs) isolated from drought-stressed Arabidopsis leaves and identifying EARLY RESPONSIVE TO DEHYDRATION 7 (ERD7) as a putative LD protein. Observations provide new insight to ERD7 and the SD-containing family of proteins in plants and suggest that ERD7 may be involved in functional aspects of plant stress response that also include localization to the LD surface.
Arabidopsis Thaliana--Myzus Persicae Interaction: Shaping the Understanding of Plant Defense Against Phloem-Feeding Aphids
This review article summarizes recent studies that have exploited the compatible interaction between Arabidopsis and the green peach aphid (GPA) to understand the molecular and physiological mechanisms utilized by plants to control aphid infestation, as well as genes and mechanisms that contribute to susceptibility.
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