Search Results

Planar shock compression of spark plasma sintered B4C and B4C-TiB2 ceramic composites
Article describes how blending of ceramic constituent phases enhances sinterability and performance in high strength ceramics. The authors describe how a near fully dense blended boron carbide (B4C)-titanium diboride (TiB2) composite produced through spark plasma sintering (SPS) is probed to understand the mechanical performance under dynamic uniaxial strain, or shock compression.
Hedgehog signaling is involved in acquired resistance to KRASG12C inhibitors in lung cancer cells
Article states that although KRASG12C inhibitors have shown promising activity in lung adenocarcinomas harboring KRASG12C, acquired resistance to these therapies eventually occurs in most patients. The authors report that the hedgehog signal is induced by KRASG12C inhibitors and mediates KRAS re-expression in cancer cells treated with a KRASG12C inhibitor.
Multimodal and multiscale strengthening mechanisms in Al-Ni-Zr-Ti-Mn alloy processed by laser powder bed fusion additive manufacturing
Article describes how the unique thermokinetics of laser-powder bed fusion additive manufacturing has been exploited for development of a novel high strength Al-Ni-Ti-Zr-Mn alloy. The authors say that the addition of 0.5 wt% Mn leads to extraordinary improvement in ultimate tensile strength (502 MPa) and work hardening due to the activation of two Mn-induced strengthening mechanisms
Light Confinement in Twisted Single-Layer 2D+ Moiré Photonic Crystals and Bilayer Moiré Photonic Crystals
Article reporting optical properties of twisted single-layer 2D+ moiré photonic crystals where there is a weak modulation in z direction, and bilayer moiré-overlapping-moiré photonic crystals. This study leads to a potential application of 2D+ moiré photonic crystal in future on-chip optoelectronic integration.
Mesenchymal stem cells aligned and stretched in self-assembling peptide hydrogels
Article describes how the presented research highlights a novel approach using fmoc-protected peptide hydrogels for the encapsulation and stretching of mesenchymal stem cells. This study utilized a custom mechanical stretching device with a PDMS chamber to stretch human mesenchymal stem cells encapsulated in Fmoc hydrogels.
Surface Nanostructures Enhanced Biocompatibility and Osteoinductivity of laser-Additively Manufactured CoCrMo Alloys
Article describes how cobalt–chromium–molybdenum (CoCrMo) alloys are widely used in orthopedic implants due to their excellent corrosion and wear resistance and superior mechanical properties. In this study, the authors prepared CoCrMo alloys with surface nanostructures of various aspect ratios (AR) using laser-directed energy deposition (L-DED) and biocorrosion.
Phase-Specific Damage Tolerance of a Eutectic High Entropy Alloy
Article describes how phase-specific damage tolerance was investigated for the AlCoCrFeNi2.1 high entropy alloy with a lamellar microstructure of L12 and B2 phases. Distinct differences in micro-scale deformation mechanisms were reflected in post-compression fractography, with L12-phase cantilevers showing typical characteristics of ductile failure, including the activation of multiple slip lanes, shear lips at the notch edge, and tearing inside the notch versus quasi-cleavage fracture with cleavage facets and a river pattern on the fracture surface for the B2-phase cantilevers.
Reconstructing aerosol optical depth using spatiotemporal Long Short-Term Memory convolutional autoencoder
Article describes how Aerosol Optical Depth (AOD)is a crucial atmospheric parameter in comprehending climate change, air quality, and its impacts on human health. This study presents a new solution to this challenge by providing a long-term, gapless satellite-derived AOD dataset for Texas from 2010 to 2022, utilizing Moderate Resolution Imaging Spectroradiometer (MODIS) multi-angle implementation of atmospheric correction (MAIAC) products.
Laser printed amorphous magnesium alloy: Microstructure, mechanical properties, and degradation behavior
Article describes how, amorphous magnesium alloy, especially Mg-Zn-Ca series, has been receiving continuous attention in biomedical field, because of its favorable corrosion resistance, suitable modulus and biocompatibility. In this work, laser powder bed fusing with unique characteristics of rapid solidification and layer-by-layer fashion was used to fabricate bulk Mg-Zn-Ca and Mg-Zn-Ca-Y amorphous parts.
Construction and characterization of superhydrophobic wood coatings using one-step technique
Article describes how this study was aiming at enhancing the stain resistance and durability of varnish on wood surfaces, a super hydrophobic solution was created by blending the synthetic ZIF-8/paraffin with Hexadecyltrimethoxysilane at a specified mass ratio. This superhydrophobic mixture was then directly applied onto the wood varnish coating using a one-step method.
Properties of Hyper-Elastic-Graded Triply Periodic Minimal Surfaces
Article describes how the mechanical behaviors of three distinct lattice structures-Diamond, Gyroid, and Schwarz-synthesized through vat polymerization were meticulously analyzed. This study aimed to elucidate the intricacies of these structures in terms of their stress-strain responses.
Detergent-Based Decellularization for Anisotropic Cardiac-Specific Extracellular Matrix Scaffold Generation
Article describes how cell-derived extracellular matrix has become increasingly popular in tissue engineering applications due to its ability to provide tailored signals for desirable cellular responses. The objective of this study was to assess the efficacy of two detergent-based decellularization methods: a combination of ethylenediaminetetraacetic acid and sodium dodecyl sulfate and a combination of sodium deoxycholate and deoxyribonuclease.
The Interface Strengthening of Multi-Walled Carbon Nanotubes/Polylactic Acid Composites via the In-Loop Hybrid Manufacturing Method
Article describes how in this study, a new in-loop hybrid manufacturing method is proposed for fabricating multi-walled carbon nanotube (MWCNTs)/polylactic acid (PLA) composites. Molecular dynamics simulations were conducted in conjunction with experiments to reveal the mechanism of the proposed method for improving the interfacial performance of MWCNTs/PLA.
An Optimized Control System for the Independent Control of the Inputs of the Doherty Power Amplifier
Article describes how this study presents a systematic design of an optimized drive signal control system for 2.5 GHz Doherty power amplifiers (DPAs). In this manuscript, the authors analyzed and compared the PAE of the DPA and parallel-connected PA for diverse input signals generated using a designed optimized control system
Accuracy-Constrained Efficiency Optimization and GPU Profiling of CNN Inference for Detecting Drainage Crossing Locations
Article describes how the accurate and efficient determination of hydrologic connectivity has garnered significant attention from both academic and industrial sectors due to its critical implications for environment management. To address these challenges, the focus of the author's study is on detecting drainage crossings through the application of advanced convolutional neural networks.
Pareto Optimization of CNN Models via Hardware-Aware Neural Architecture Search for Drainage Crossing Classification on Resource-Limited Devices
Article describes how embedded devices, constrained by limited memory and processors, require deep learning models to be tailored to their specifications. This research explores customized model architectures for classifying drainage crossing images.
Securing Industrial Control Systems: Components, Cyber Threats, and Machine Learning-Driven Defense Strategies
Article describes how Industrial Control Systems (ICS), which include Supervisory Control and Data Acquisition (SCADA) systems, Distributed Control Systems (DCS), and Programmable Logic Controllers (PLC), play a crucial role in managing and regulating industrial processes. This article presents an overview of ICS security, covering its components, protocols, industrial applications, and performance aspects.
Multifaceted Shape Memory Polymer Technology for Biomedical Application: Combining Self-Softening and Stretchability Properties
Article describes how thiol-ene polymers are a promising class of biomaterials with a wide range of potential applications, including organs-on-a-chip, microfluidics, drug delivery, and wound healing. This study investigated the incorporation of di-acrylate chain extenders to improve the stretchability and conformability of those flexible thiol-ene polymers.
Investigation on drying kinetics analysis of gooseberry slices dried under open sun
Article describes an experimental analysis of the drying behavior of gooseberry slices dried in the open sun. The authors used the hot air dryer method, and found that the moisture content of gooseberry slices in their initial condition was estimated to be 87.81% wet-basis.
Accessibility and Mechanical Stability of Nanoporous Zinc Oxide and Aluminum Oxide Coatings Synthesized via Infiltration of Polymer Templates
Article describes how the conformal nanoporous inorganic coatings with accessible pores that are stable under applied thermal and mechanical stresses represent an important class of materials used in the design of sensors, optical coatings, and biomedical systems. Authors synthesize porous AlOx and ZnO coatings by the sequential infiltration synthesis (SIS) of two types of polymers that enable the design of porous conformal coatings.
Ideal plasticity and shape memory of nanolamellar high-entropy alloys
Article describes how understanding the relationship among elemental compositions, nanolamellar microstructures, and mechanical properties enables the rational design of high-entropy alloys (HEAs). In this article the authors construct nanolamellar Alx-CoCuFeNi HEAs with alternating high- and low-Al concentration layers and explore their mechanical properties using a combination of molecular dynamic simulation and density functional theory calculation.
Author Correction: MXene/graphene oxide nanocomposites for friction and wear reduction of rough steel surfaces
Correction to the article points out an error in Figure 1e. The figure is corrected in this article.
Nanotopographical Cues Tune the Therapeutic Potential of Extracellular Vesicles for the Treatment of Aged Skeletal Muscle Injuries
Article describes how skeletal muscle regeneration relies on the tightly temporally regulated lineage progression of muscle stem/progenitor cells (MPCs) from activation to proliferation and finally, differentiation. The authors developed an engineering strategy to tune the therapeutic potential of EVs using nanotopographical cues.
Analyzing influence of COVID-19 on crypto & financial markets and sentiment analysis using deep ensemble model
Article describes how COVID-19 affected the world's economy severely and increased the inflation rate in both developed and developing countries. This study performs an analysis of the impact of COVID-19 on public opinion and sentiments regarding the financial markets and crypto markets.
Suppression of the antitumoral activity of natural killer cells under indirect coculture with cancer-associated fibroblasts in a pancreatic TIME-on-chip model
Article describes how recently, natural killer cells emerged as a treatment option for various solid tumors. The effect of activated pancreatic stellate cells on natural killer cell-mediated anticancer efficacy under three-dimensional coculture conditions was investigated.
Highly Pseudocapacitive Storage Design Principles of Heteroatom-Doped Graphene anode in Calcium-Ion Batteries
Article describes how pseudocapacitive storage of multivalent ions, especially Ca2+, in heteroatom-doped carbon nanomaterials is promising to achieve both high energy and power densities, but there is the lack of pseudocapacitive theories that enable rational design of the materials for calcium-ion batteries.
FZ-GPU: A Fast and High-Ratio Lossy Compressor for Scientific Computing Applications on GPUs
Article describes how today's large-scale scientific applications running on high-performance computing (HPC) systems generate vast data volumes. Thus, data compression is becoming a critical technique to mitigate the storage burden and data-movement cost. In this paper, the authors develop a fast and high- ratio error-bounded lossy compressor on GPUs for scientific data (called FZ-GPU).
Harnessing nanofiber alignment and pore size to promote stem cell self-renewal and differentiation
Article describes how stem cell therapy holds immense potential for regenerative medicine, but its applications are limited due to the loss of pluripotency during in vitro expansion. This study reveals that the arrangement of electrospun fibers aligns with the distribution and strength of the electric field through both experimentation and simulation.
Polypropylene-Based Polymer Locking Ligation System Manufacturing by the Ultrasonic Micromolding Process
Article describes how in recent years, there has been a growing demand for biocompatible medical devices on the microscale. The authors of the article extensively investigated various processing parameters such as vibration amplitude, temperature, and injection velocity.
MXene/graphene oxide nanocomposites for friction and wear reduction of rough steel surfaces
Article describes how development of solid lubricant materials that render reliable performance in ambient conditions, are amenable to industrial size and design complexities, and work on engineered surfaces is reported. This report presents the holistic exploration and correlation of structure-property-processing pertaining to the advancement of solid lubrication science.
Tribocatalytically-active nickel/cobalt phosphorous films for universal protection in a hydrocarbon-rich environment
Article describes how high-contact stresses generated at the sliding interfaces during their relative movement provide a unique combination of local heating and shear- and load-induced compression conditions. The authors of the article employ the electrodeposition process to design a coating composed of a hard cobalt-phosphorous matrix with the inclusion of tribocatalytically-active nickel clusters.
High-Fidelity Conjugate Heat Transfer Simulation of Micro-Channel Heat Exchanger
Article describes how high-fidelity conjugate heat transfer simulations are used to model a micro-channel heat exchanger (MCHE) in a crossflow to study its thermal-hydraulic performance. Three different microchannel geometries, namely circular, triangular, and square with louver-shaped fins, are considered.
PPAD: a deep learning architecture to predict progression of Alzheimer’s disease
Article asserts that Alzheimer’s disease (AD) is a neurodegenerative disease that affects millions of people worldwide. The authors of the article propose two deep learning architectures based on RNN, namely Predicting Progression of Alzheimer’s Disease (PPAD) and PPAD-Autoencoder.
SUPREME: multiomics data integration using graph convolutional networks
Article states that, to pave the road towards precision medicine in cancer, patients with similar biology ought to be grouped into same cancer subtypes. On breast cancer subtyping, unlike existing tools, SUPREME generates patient embeddings from multiple similarity networks utilizing multiomics features and integrates them with raw features to capture complementary signals.
Numerical Analysis of Cambered Plate Configurations under Low Reynolds Numbers and at a Low-Density Condition
Article discusses how, after one year of operation, the Ingenuity rotorcraft and the Perseverance rover continue their exploration missions on Mars. Succeeding the technology demonstration phase, by proving its flight capabilities, Ingenuity transitioned to a new mission stage to explore modes of flight exploration for future scouting missions. The author's research intends to analyze, using numerical simulations, the aerodynamic conditions such as those experienced by Ingenuity during its flight missions.
NextGen-Malloc: Giving Memory Allocator Its Own Room in the House
Article describes how memory allocation and management have a significant impact on performance and energy of modern applications. The authors observe that performance can vary by as much as 72% in some applications based on which memory allocator is used, and in this paper, the authors make a case for offloading memory allocation (and other similar management functions) from main processing cores to other processing units to boost performance, reduce energy consumption, and customize services to specific applications or application domains.
Boosting Piezoelectricity by 3D Printing PVDF-MoS2 Composite as a Conformal and High-Sensitivity Piezoelectric Sensor
Article describes how additively manufactured flexible and high-performance piezoelectric devices are highly desirable for sensing and energy harvesting of 3D conformal structures. This study reports a significantly enhanced piezoelectricity in polyvinylidene fluoride (PVDF) achieved through the in situ dipole alignment of PVDF within PVDF-2D molybdenum disulfide composite by 3D printing.
Comparison of Thermal Effectiveness and Crevice Corrosion Risk of Fin Geometry on All-Aluminum Microchannel Heat Exchangers
Article all-aluminum microchannel heat exchangers have recently gained popularity in the heating, ventilation, and air conditioning industry. Despite their attractive thermal performance design, these heat exchangers make coils used in automotive, commercial, and residential applications prone to crevice corrosion. This study uses high-fidelity conjugate heat transfer simulations to model a micro channel heat exchanger system that includes fins and tubes with crossflow to compare their thermal effectiveness to gain insight into potential crevice corrosion of the MCHE alloy.
Underlying factors determining grain morphologies in high-strength titanium alloys processed by additive manufacturing
Article describes how, in recent research, additions of solute to Ti and some Ti-based alloys have been employed to produce equiaxed microstructures when processing these materials using additive manufacturing. The present study develops a computational scheme for guiding the selection of such alloying additions, and the minimum amounts required, to effect the columnar to equiaxed microstructural transitions.
Thermal heat transfer and energy modeling through incorporation of phase change materials (PCMs) into polyurethane foam
Article describes how decreasing HVAC energy consumption through insulation effectiveness enables low energy use, low carbon emissions, and high thermal comfort in sustainable buildings. In this paper, two PCMs with transition temperature above and below the outdoor temperature incorporated in highly porous flexible polyurethane foam were evaluated using a one-dimensional (1D) foam core panel built in COMSOL Multiphysics®.
NRPreTo: A Machine Learning-Based Nuclear Receptor and Subfamily Prediction Tool
Article asserts that the nuclear receptor (NR) superfamily includes phylogenetically related ligand-activated proteins, which play a key role in various cellular activities. The authors developed Nuclear Receptor Prediction Tool (NRPreTo), a two-level NR prediction tool with a unique training approach where in addition to the sequence-based features used by existing NR prediction tools, six additional feature groups depicting various physiochemical, structural, and evolutionary features of proteins were utilized.
Light-Controlled Cell–Cell Assembly Using Photocaged Oligonucleotides
Article asserts that while techniques that allow one to control the arrangement of cells and direct contact between different cell types have been developed that expand upon simple co-culture methods, specific control over heterojunctions that form between cells is not easily accomplished with current methods, such as 3D cell-printing. In this article, DNA-mediated cell interactions are combined with cell-compatible photolithographic approaches to control cell assembly.
Advanced Air Mobility Operation and Infrastructure for Sustainable Connected eVTOL Vehicle
Article discusses how advanced air mobility (AAM) is an emerging sector in aviation aiming to offer secure, efficient, and eco-friendly transportation utilizing electric vertical takeoff and landing (eVTOL) aircraft. This paper introduces a novel concept addressing future flight challenges and proposes a framework for integrating operations, infrastructure, connectivity, and ecosystems in future air mobility.
Feasibility of PROMIS using computerized adaptive testing during inpatient rehabilitation
Article describes how there has been an increased significance on patient-reported outcomes in clinical settings. The authors aimed to evaluate the feasibility of administering patient-reported outcome measures by computerized adaptive testing (CAT) using a tablet computer with rehabilitation inpatients, assess workload demands on staff, and estimate the extent to which rehabilitation inpatients have elevated T-scores on six Patient Reported Outcomes Measurement Information System (PROMIS) measures.
A Critical Review of Laser Shock Peening of Aircraft Engine Components
Article describes how many aviation accidents are caused by the failure of aircraft engine components, and engine blades are especially vulnerable to high-cycle fatigue fracture in severe working environments as well as to impact damage caused by foreign objects. This review provides an overview of the development of LSP for use in treating aircraft engine components over the past three decades, with a brief introduction to the development of high-energy pulsed lasers for LSP.
Tuning the temperature range of superelastic Ni-Ti alloys for elastocaloric cooling via thermal processing
Article describes how caloric cooling enlisting solid-state refrigerants is potentially a promising eco-friendly alternative to conventional cooling based on vapor compression. Here, the authors have explored tuning the operation temperature range of Ni50.8Ti49.2 for elastocaloric cooling. In particular, they have studied the effect of thermal treatments (a.k.a. aging) on the transformation temperature, superelasticity, and elastocaloric effects of Ni50.8Ti49.2 shape memory alloy tubes.
Mapping hierarchical and heterogeneous micromechanics of a transformative high entropy alloy by nanoindentation and machine learning augmented clustering
Article describes how conventional macromechanical tests provide limited insights into complex hierarchical deformation behavior of a transformative high entropy alloy (HEA). In this work, a high throughput microstructure-micromechanical correlative study is presented by combining high-resolution nanoindentation, site-specific microscopy, and Gaussian mixture model (GMM) clustering.
A Review of Rehabilitative and Assistive Technologies for Upper-Body Exoskeletal Devices
Authors state that this journal review article focuses on the use of assistive and rehabilitative exoskeletons as a new opportunity for individuals with diminished mobility. Overall, this article serves as a valuable resource for individuals working in the field of assistive and rehabilitative exoskeletons, providing insight into the state of the art and potential areas for improvement.
FlexiChain 3.0: Distributed Ledger Technology-Based Intelligent Transportation for Vehicular Digital Asset Exchange in Smart Cities
Article describes how, due to the enormous amounts of data being generated between users, Intelligent Transportation Systems (ITS) are complex Cyber-Physical Systems that necessitate a reliable and safe infrastructure. In this work, the authors explore Distributed Ledger Technology (DLT) and collect data about consensus algorithms and their applicability to be used in the IoV as the backbone of ITS.
Room and Elevated Temperature Sliding Friction and Wear Behavior of Al0.3CoFeCrNi and Al0.3CuFeCrNi2 High Entropy Alloys
Article discusses how, in this study, processing–structure–property relations were systematically investigated at room and elevated temperatures for two FCC Al0.3CoFeCrNi and Al0.3CuFeCrNi2 high-entropy alloys (HEAs), also known as complex concentrated alloys (CCAs), prepared by conventional arc-melting. It was determined that both alloys exhibit FCC single-phase solid solution structure. Micro-indentation and sliding wear tests were performed to study the hardness and tribological behavior and mechanisms at room and elevated temperatures.
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