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Thymoquinone overcomes chemoresistance and enhances the anticancer effects of bortezomib through abrogation of NF-κB regulated gene products in multiple myeloma xenograft mouse model

Description: Article investigates whether thymoquinone (TQ), a bioactive constituent of black seed oil, could suppress the proliferation and induce chemosensitization in human myeloma cells and xenograft mouse model. Overall, the results demonstrate that TQ can enhance the anticancer activity of bortezomib in vitro and in vivo and may have a substantial potential in the treatment of MM.
Date: December 18, 2013
Creator: Siveen, Kodappully Sivaraman; Mustafa, Nurulhuda; Li, Feng; Kannaiyan, Radhamani; Ahn, Kwang Seok; Kumar, Alan Prem et al.
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Partner: UNT College of Arts and Sciences
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γ-tocotrienol inhibits angiogenesis-dependent growth of human hepatocellular carcinoma through abrogation of AKT/mammalian target of rapamycin pathway in an orthotopic mouse model

Description: Article describing an investigation into whether γ-tocotrienol can abrogate angiogenesis-mediated tumor growth in hepatocellular carcinoma (HCC) and if so, through what molecular mechanisms.
Date: March 31, 2014
Creator: Siveen, Kodappully Sivaraman; Ahn, Kwang Seok; Ong, Tina H.; Shanmugam, Muthu K.; Li, Feng; Yap, Wei Ney et al.
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Partner: UNT College of Arts and Sciences
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Association of Host and Microbial Species Diversity across Spatial Scales in Desert Rodent Communities

Description: Article describes study in which researchers employed a natural gradient of rodent species richness and quantified bacterial communities in rodent blood at several hierarchical spatial scales to test the hypothesis that associations between host and microbial species diversity will be positive in communities dominated by organisms with broad niches sampled at large scales.
Date: October 24, 2014
Creator: Gavish, Yoni; Kedem, Hadar; Messika, Irit; Cohen, Carmit; Toh, Evelyn; Munro, Daniel et al.
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Partner: UNT College of Arts and Sciences
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Negative Regulation of Signal Transducer and Activator of Transcription-3 Signalling Cascade by Lupeol Inhibits Growth and Induces Apoptosis in Hepatocellular Carcinoma Cells

Description: In this article, the authors evaluate the effect of lupeol on STAT3 signalling cascade and its regulated functional responses in hepatocellular carcinoma (HCC) cells. Constitutive activation of signal transducer and activator of transcription signalling 3 (STAT3) has been linked with survival, proliferation and angiogenesis in a wide variety of malignancies including HCC. Lupeol exhibited its potential anticancer effects in HCC through the downregulation of STAT3-induced pro-survival signalling… more
Date: August 7, 2014
Creator: Siveen, Kodappully Sivaraman; Nguyen, An H.; Lee, J. H.; Li, Feng; Singh, S. S.; Kumar, Alan Prem et al.
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Partner: UNT College of Arts and Sciences
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Introducción a la Sección Especial de Revista Bosque. Avances de una red de sitios de estudios ecológicos a largo plazo en el suroeste de Sudamérica

Description: This article is the forward to a special section on long-term ecological research in Chile. It briefly introduces the main topics and ideas of each of the articles and comment on their relevance in the context of research and monitoring of Chilean ecosystems and in the perspective of global change research.
Date: 2014
Creator: Armesto, Juan J., 1953-; Nuñez-Avila, Mariela; Donoso, Pablo & Rozzi, Ricardo, 1960-
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Partner: UNT College of Arts and Sciences
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Spatially Periodic Electromagnetic Force Field For Plasma Confinement and Control

Description: In this article, a theoretical understanding is developed of the single-particle reflection properties of a force field, considering the incident charged particles to have a non-drifting, isotropic velocity distribution. Classical trajectory Monte Carlo simulations and analytical modeling are employed. The initiation of an experimental effort to study force fields is described.
Date: April 17, 2012
Creator: Ordonez, Carlos A.; Pacheco, J. L. & Weathers, Duncan L.
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Partner: UNT College of Arts and Sciences
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Structural Consideration in Designing Organotin Polyethers to Arrest the Growth of Breast Cancer Cells In Vitro

Description: The article looks at antitumor activity using a matched pair of cell lines MDA-MB-231 cells that are estrogen-independent, estrogen receptor negative and MCF-7 cells, a cell line that is estrogen receptor (ER) positive. Those polyethers that contained a O-phenyl unit were able to significantly inhibit the non-estrogen sensitive cell line but were much less effective against the estrogen sensitive cell line; that is, the human breast cancer cell line MDA-MB-231 showed better test results for pol… more
Date: April 15, 2011
Creator: Carraher, Charles E., Jr.; Roner, Michael R.; Shahi, Kimberly & Barot, Girish
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Partner: UNT College of Arts and Sciences
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Antiviral Activity of Metal-Containing Polymers—Organotin and Cisplatin-Like Polymers

Description: This article examines the use of metal-containing polymers as a novel class of antivirals. Polymers containing platinum and to a lesser extent tin, have repeatedly demonstrated antitumor activity in vitro and in vivo against a variety of cell and tumor types. The mechanisms responsible for the antitumor activity include inducing a delay in cell proliferation and sister chromatid exchanges blocking tumor growth.
Date: May 27, 2011
Creator: Roner, Michael R.; Carraher, Charles E., Jr.; Shahi, Kimberly & Barot, Girish
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Partner: UNT College of Arts and Sciences
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An Updating System for the Gridded Population Database of China Based on Remote Sensing, GIS and Spatial Database Technologies

Description: Describes the development of a Spatial Population Updating System (SPUS) for updating the gridded population database of China based on remote sensing, GIS and spatial database technologies, with a spatial resolution of 1 km by 1 km.
Date: February 20, 2009
Creator: Yang, Xiaohuan; Huang, Yaohuan; Dong, Pinliang; Jiang, Dong & Liu, Honghui
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Partner: UNT College of Arts and Sciences
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The First Stalin Mass Operation (1927)

Description: This article based on new archival documents introduces a new episode of mass operations, which took place in June and July of 1927 and was directed against the broad group of “anti-Soviet” forces. It preceded many practices of mass terror of the 1930s with judicial and extra-legal mechanisms. The goal of this article is to explain motivations, justifications, and mechanisms of this repressive campaign and to put this episode in the wider context of Soviet terror. Facing the combination of a pe… more
Date: January 2013
Creator: Velikanova, Olga V.
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Partner: UNT College of Arts and Sciences
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Technical Memorandum: Lewisville Lake Watershed Protection and Management Strategies

Description: With a current population of just over half a million and a 2030 projected population of approximately one million, expansion throughout Denton County shows no sign of slowing down (NCTCOG). Increasingly, freshwater resources are also facing increased pressure from this urban expansion. Effective assessment and management techniques are necessary to protect the diversity of ecosystem services found within fluvial ecosystems and to mitigate current and future conditions of environmental stresso… more
Date: September 2007
Creator: Atkinson, Samuel F.; Hunter, Bruce Allan; English, April; Boe, Brian & Dameron, Matt
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Partner: UNT College of Arts and Sciences
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Some numerical analyses on the solubility of vanillin in Carbitol® + water solvent mixtures

Description: This article reports solubility values of vanillin (component 3) in 2-(2-ethoxyethoxy)ethanol (Carbitol®, component 1) + water (component 2) mixtures at five temperatures from 298.15 to 318.15 K correlated with the Jouyban-Acree model combined with van't Hoff or Apelblat equations, and obtains models in second degree regarding the mixtures compositions.
Date: May 25, 2015
Creator: Martínez, Fleming; Jouyban, Abolghasem & Acree, William E. (William Eugene)
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Partner: UNT College of Arts and Sciences
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Cotton CENTRORADIALIS/TERMINAL FLOWER 1/SELF-PRUNING genes functionally diverged to differentially impact plant architecture

Description: This article characterizes the CETS gene family from tetraploid cotton in order to understand the regulation of cotton architecture and exploit these principles to enhance crop productivity.
Date: September 10, 2018
Creator: Prewitt, Sarah F.; Ayre, Brian G. & McGarry, Roisin C.
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Partner: UNT College of Arts and Sciences
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Attributive Constructions in Saanich

Description: This paper gives a descriptive sketch of the various structures of the Saanich dialect of North Straits Salish has to express attribution and to look at structures similar to those designated relative clauses in other Salishan languages from a cross-linguistic and pan-Salishan point of view.
Date: August 1978
Creator: Montler, Timothy
Item Type: Refine your search to only Paper
Partner: UNT College of Arts and Sciences
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Klallam Demonstratives

Description: This paper updates and expands upon the componential analysis provided by Thompson and Thompson 1071 of the Klallam language's set of demonstrative determiners.
Date: 2007
Creator: Montler, Timothy
Item Type: Refine your search to only Paper
Partner: UNT College of Arts and Sciences
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