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Elevated CO2 increases energetic cost and ion movement in the marine fish intestine

Description: Article describes study which aimed to gain resolution in assessing the energetic demand associated with acid-base regulation by examining ion movement and O2 consumption rates of isolated intestinal tissue from Gulf toadfish acclimated to control or 1900 μatm CO2 (projected for year 2300).
Date: September 29, 2016
Creator: Heuer, Rachael M. & Grosell, Martin
Partner: UNT College of Arts and Sciences
open access

SPHK1 regulates proliferation and survival responses in triple-negative breast cancer

Description: Article describes study suggesting that the inhibation of sphingosine kinase 1 (SPHK1) can attenuate ERK1/2 and AKT signaling and reduce growth of triple-negative breast cancer (TNBC) cells in vitro and in a xenograft SCID mouse model.
Date: March 27, 2014
Creator: Datta, Arpita; Loo, Ser Yue; Huang, Baohua; Wong, Lingkai; Tan, Sheryl S.L.; Tan, Tuan Zea et al.
Partner: UNT College of Arts and Sciences
open access

Generalized second-order parametric optimality conditions in semiinfinitediscrete minmax fractional programming and second order (F,β,φ,ρ,θ,m)-univexity

Description: Article discusses establishing numerous sets of generalized second order paramertic sufficient optimality conditions for a semiinfinite discrete minmax fractional programming problem, while the results on semiinfinite discrete minmax fractional programming problem achieved based on some partitioning schemes under various types of generalized second order univexity assumptions.
Date: February 28, 2016
Creator: Verma, Ram U. & Zalmai, G. J.
Partner: UNT College of Arts and Sciences
open access

Effect of selection for commercially productive traits on the plasticity of cardiovascular regulation in chicken breeds during embryonic development

Description: Article investigates basic cardiovascular physiology in the Red Junglefowl, the broiler, and the White Leghorn breeds at 90% of incubation. The authors aimed to identify breed-specific features of arterial blood pressure and heart rate as well as the physiological mechanisms regulating them. They concluded that selection for rapid growth shifts cardiovascular regulatory plasticity to emphasize mechanisms that modulate pressure, and that selection for egg-laying capacity emphasizes mechanisms th… more
Date: October 1, 2012
Creator: Crossley, Dane A., II & Altimiras, J.
Partner: UNT College of Arts and Sciences
open access

Thymoquinone overcomes chemoresistance and enhances the anticancer effects of bortezomib through abrogation of NF-κB regulated gene products in multiple myeloma xenograft mouse model

Description: Article investigates whether thymoquinone (TQ), a bioactive constituent of black seed oil, could suppress the proliferation and induce chemosensitization in human myeloma cells and xenograft mouse model. Overall, the results demonstrate that TQ can enhance the anticancer activity of bortezomib in vitro and in vivo and may have a substantial potential in the treatment of MM.
Date: December 18, 2013
Creator: Siveen, Kodappully Sivaraman; Mustafa, Nurulhuda; Li, Feng; Kannaiyan, Radhamani; Ahn, Kwang Seok; Kumar, Alan Prem et al.
Partner: UNT College of Arts and Sciences
open access

γ-tocotrienol inhibits angiogenesis-dependent growth of human hepatocellular carcinoma through abrogation of AKT/mammalian target of rapamycin pathway in an orthotopic mouse model

Description: Article describing an investigation into whether γ-tocotrienol can abrogate angiogenesis-mediated tumor growth in hepatocellular carcinoma (HCC) and if so, through what molecular mechanisms.
Date: March 31, 2014
Creator: Siveen, Kodappully Sivaraman; Ahn, Kwang Seok; Ong, Tina H.; Shanmugam, Muthu K.; Li, Feng; Yap, Wei Ney et al.
Partner: UNT College of Arts and Sciences
open access

Association of Host and Microbial Species Diversity across Spatial Scales in Desert Rodent Communities

Description: Article describes study in which researchers employed a natural gradient of rodent species richness and quantified bacterial communities in rodent blood at several hierarchical spatial scales to test the hypothesis that associations between host and microbial species diversity will be positive in communities dominated by organisms with broad niches sampled at large scales.
Date: October 24, 2014
Creator: Gavish, Yoni; Kedem, Hadar; Messika, Irit; Cohen, Carmit; Toh, Evelyn; Munro, Daniel et al.
Partner: UNT College of Arts and Sciences
open access

Negative Regulation of Signal Transducer and Activator of Transcription-3 Signalling Cascade by Lupeol Inhibits Growth and Induces Apoptosis in Hepatocellular Carcinoma Cells

Description: In this article, the authors evaluate the effect of lupeol on STAT3 signalling cascade and its regulated functional responses in hepatocellular carcinoma (HCC) cells. Constitutive activation of signal transducer and activator of transcription signalling 3 (STAT3) has been linked with survival, proliferation and angiogenesis in a wide variety of malignancies including HCC. Lupeol exhibited its potential anticancer effects in HCC through the downregulation of STAT3-induced pro-survival signalling… more
Date: August 7, 2014
Creator: Siveen, Kodappully Sivaraman; Nguyen, An H.; Lee, J. H.; Li, Feng; Singh, S. S.; Kumar, Alan Prem et al.
Partner: UNT College of Arts and Sciences
open access

Introducción a la Sección Especial de Revista Bosque. Avances de una red de sitios de estudios ecológicos a largo plazo en el suroeste de Sudamérica

Description: This article is the forward to a special section on long-term ecological research in Chile. It briefly introduces the main topics and ideas of each of the articles and comment on their relevance in the context of research and monitoring of Chilean ecosystems and in the perspective of global change research.
Date: 2014
Creator: Armesto, Juan J., 1953-; Nuñez-Avila, Mariela; Donoso, Pablo & Rozzi, Ricardo, 1960-
Partner: UNT College of Arts and Sciences
open access

Spatially Periodic Electromagnetic Force Field For Plasma Confinement and Control

Description: In this article, a theoretical understanding is developed of the single-particle reflection properties of a force field, considering the incident charged particles to have a non-drifting, isotropic velocity distribution. Classical trajectory Monte Carlo simulations and analytical modeling are employed. The initiation of an experimental effort to study force fields is described.
Date: April 17, 2012
Creator: Ordonez, Carlos A.; Pacheco, J. L. & Weathers, Duncan L.
Partner: UNT College of Arts and Sciences
open access

Structural Consideration in Designing Organotin Polyethers to Arrest the Growth of Breast Cancer Cells In Vitro

Description: The article looks at antitumor activity using a matched pair of cell lines MDA-MB-231 cells that are estrogen-independent, estrogen receptor negative and MCF-7 cells, a cell line that is estrogen receptor (ER) positive. Those polyethers that contained a O-phenyl unit were able to significantly inhibit the non-estrogen sensitive cell line but were much less effective against the estrogen sensitive cell line; that is, the human breast cancer cell line MDA-MB-231 showed better test results for pol… more
Date: April 15, 2011
Creator: Carraher, Charles E., Jr.; Roner, Michael R.; Shahi, Kimberly & Barot, Girish
Partner: UNT College of Arts and Sciences
open access

Antiviral Activity of Metal-Containing Polymers—Organotin and Cisplatin-Like Polymers

Description: This article examines the use of metal-containing polymers as a novel class of antivirals. Polymers containing platinum and to a lesser extent tin, have repeatedly demonstrated antitumor activity in vitro and in vivo against a variety of cell and tumor types. The mechanisms responsible for the antitumor activity include inducing a delay in cell proliferation and sister chromatid exchanges blocking tumor growth.
Date: May 27, 2011
Creator: Roner, Michael R.; Carraher, Charles E., Jr.; Shahi, Kimberly & Barot, Girish
Partner: UNT College of Arts and Sciences
open access

An Updating System for the Gridded Population Database of China Based on Remote Sensing, GIS and Spatial Database Technologies

Description: Describes the development of a Spatial Population Updating System (SPUS) for updating the gridded population database of China based on remote sensing, GIS and spatial database technologies, with a spatial resolution of 1 km by 1 km.
Date: February 20, 2009
Creator: Yang, Xiaohuan; Huang, Yaohuan; Dong, Pinliang; Jiang, Dong & Liu, Honghui
Partner: UNT College of Arts and Sciences
open access

The First Stalin Mass Operation (1927)

Description: This article based on new archival documents introduces a new episode of mass operations, which took place in June and July of 1927 and was directed against the broad group of “anti-Soviet” forces. It preceded many practices of mass terror of the 1930s with judicial and extra-legal mechanisms. The goal of this article is to explain motivations, justifications, and mechanisms of this repressive campaign and to put this episode in the wider context of Soviet terror. Facing the combination of a pe… more
Date: January 2013
Creator: Velikanova, Olga V.
Partner: UNT College of Arts and Sciences
open access

Some numerical analyses on the solubility of vanillin in Carbitol® + water solvent mixtures

Description: This article reports solubility values of vanillin (component 3) in 2-(2-ethoxyethoxy)ethanol (Carbitol®, component 1) + water (component 2) mixtures at five temperatures from 298.15 to 318.15 K correlated with the Jouyban-Acree model combined with van't Hoff or Apelblat equations, and obtains models in second degree regarding the mixtures compositions.
Date: May 25, 2015
Creator: Martínez, Fleming; Jouyban, Abolghasem & Acree, William E. (William Eugene)
Partner: UNT College of Arts and Sciences
open access

Serial Verbs and Complex Paths in Klallam

Description: This article describes and illustrates the construction of complex paths and discusses the place of Klallam in a typology of motion events.
Date: 2008
Creator: Montler, Timothy
Partner: UNT College of Arts and Sciences
open access

Methods to evaluate rare variants gene-age interaction for triglycerides

Description: This article discusses the development of two statistical methods to test the gene environment interaction effect of rare variants.
Date: September 17, 2018
Creator: Huayang Gao, Tony; Zhang, Jianjun; Medina Miguelangel, Diaz & Wang, Xuexia
Partner: UNT College of Arts and Sciences
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