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Computing microRNA-gene interaction networks in pan-cancer using miRDriver

Description: This article is a study where the authors integrated the multi-omics datasets such as copy number aberration, DNA methylation, gene and microRNA expression to identify the signature microRNA-gene associations from frequently aberrated DNA regions across pan-cancer utilizing a LASSO-based regression approach.
Date: March 8, 2022
Creator: Bose, Banabithi; Moravec, Matthew & Bozdag, Serdar
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Partner: UNT College of Engineering
open access

Deep learning for peptide identification from metaproteomics datasets

Description: This article explores a proposed deep-learning-based algorithm called DeepFilter for improving peptide identifications from a collection of tandem mass spectra. The authors find that DeepFilter is believed to generalize properly to new, previously unseen peptide-spectrum-matches and can be readily applied in peptide identification from metaproteomics data.
Date: July 8, 2021
Creator: Feng, Shichao; Sterzenbach, Ryan & Guo, Xuan
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Partner: UNT College of Engineering
open access

Protein functional module identification method combining topological features and gene expression data

Description: Article conducting an intensive study on the problems of low recognition efficiency and noise in the overlapping structure of protein functional modules, based on topological characteristics of PPI network. Developing a protein function module recognition method ECTG based on Topological Features and Gene expression data for Protein Complex Identification. The experimental results show that the ECTG algorithm can detect protein functional modules better.
Date: June 8, 2021
Creator: Zhao, Zihao; Xu, Wenjun; Chen, Aiwen; Han, Yueyue; Xia, Shengrong; Xiang, ChuLei et al.
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Partner: UNT College of Engineering
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