UNT Scholarly Works - 2 Matching Results
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- A novel statistical method for rare-variant association studies in general pedigrees
- In this paper, the authors discuss a novel statistical method for rare-variant association studies in general pedigrees for quantitative traits. This method uses a retrospective view that treats the traits as fixed and the genotypes as random, which accounts for complex and undefined ascertainment of families.
- Testing rare variants for hypertension using family-based tests with different weighting schemes
- This paper proposes 4 weighting schemes for the family-based rare variants test (FBAT-v) to test for the effects of both rare and common variants across the genome.